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| 1 | Peroxisome proliferator-activated receptor gamma as a therapeutic target for hepatocellular carcinoma:Experimental and clinical scenarios显示文摘Hepatocellular carcinoma(HCC)is the most common type of liver cancer worldwide.Viral hepatitis is a significant risk factor for HCC,although metabolic syndrome and diabetes are more frequently associated with the HCC.With increasing prevalence,there is expected to be>1 million cases annually by 2025.Therefore,there is an urgent need to establish potential therapeutic targets to cure this disease.Peroxisome-proliferator-activated receptor gamma(PPARγ)is a ligand-activated transcription factor that plays a crucial role in the pathophysiology of HCC.Many synthetic agonists of PPARγsuppress HCC in experimental studies and clinical trials.These synthetic agonists have shown promising results by inducing cell cycle arrest and apoptosis in HCC cells and preventing the invasion and metastasis of HCC.However,some synthetic agonists also pose severe side effects in addition to their therapeutic efficacy.Thus natural PPARγagonists can be an alternative to exploit this potential target for HCC treatment.In this review,the regulatory role of PPARγin the pathogenesis of HCC is elucidated.Furthermore,the experimental and clinical scenario of both synthetic and natural PPARγagonists against HCC is discussed.Most of the available literature advocates PPARγas a potential therapeutic target for the treatment of HCC. | Swati Katoch Vinesh Sharma Vikram Patial | 2022 | World Journal of Gastroenterology2022，28，28： | 2 |
| 2 | Low-cost multiple-bit encoded chipless RFID tag using stepped impedance resonator显示文摘 | Nijas C M Vinesh P V Sujith R | 2014 | IEEE Transactions on Antennas and Propagation2014，62，9： | 1 |
| 3 | Immersive learning system for manufacturing induslries 显示文摘 | Hiran Jude Femandes Vinesh H Raja Julian Eyre | 2003 | Computers in Industry (S0166-3615)2003，51，1： | 1 |
| 4 | Optimum level of goal mapping in a reengineering environment显示文摘 | Kiran Jude Femandes Vinesh Rajajiju Antony | 2001 | Business Process Management Journal2001，7，1： | 1 |
| 5 | Screening of selected ethnomedicinal plants from South Africa for larvicidal activity against the mosquito Anopheles arabiensis 显示文摘 | Rajendra Maharaj Vinesh Maharaj Neil R Crouch | 2012 | Malaria Journal2012，，： | 1 |
| 6 | Immersive Learning system for manufacturing industries 显示文摘 | Hirart Jude Femandes Vinesh H Raja Juliart Eyre | 2003 | Computers in Industry (S0166-3615)2003，51，1： | 1 |
| 7 | Immersive Learning System for Manufacturing Industries显示文摘 | Kiran Jude Fernandes Vinesh H Raja | 2003 | Computers in Industry2003，51，1： | 1 |
| 8 | Maize genotypes show striking differences for induction and regeneration of haploid wheat embryos in wheat × maize system显示文摘 | Vinesh Verma Bains N S Nanda G S | 1999 | Crop Science1999，39，： | 1 |
| 9 | Mapping quantitative trait loci for flag leaf senescence as a yield determinant in winter wheat under optimal and drought-stressed environments显示文摘 | VINESH V FOULKES M J WORLAND A J | | 0，，03： | 1 |
| 10 | Rapid and cost-effective manufacturing of high-integrity aerospace components显示文摘 | Vinesh Raja Shujun Zhang John Garside Chris Ryall David Wimpenny | 2006 | The International Journal of Advanced Manufacturing Technology (-)2006，，7： | 1 |
| 11 | Rapid and cost-effective manufacturing of high-integrity aerospace components 显示文摘 | Vinesh Raja | 2006 | Int J Adv Manuf Technol2006，，27： | 1 |
| 12 | 瑰丽硬线条——孟买Auriga餐厅酒吧显示文摘整个建筑外部由褶曲铝材质组成的网状结构覆盖,且每个板块的角度各不相同。这种网状几何结构相应地延伸到一层酒吧室内,盘附在墙面,天花,楼梯间,吧台以及圆柱上。不同颜色的灯光照射在半开合的电镀金属条板上,令空间呈现出时而冷酷,时而迷幻的丰富表情。金属造型营造出抽象的雕塑感,给空间更添一分张扬的个性。 | Sanjay Puri Madhavi Belsare Vinesh Gandhi 张妍钰 | 2013 | 设计家2013，，6： | 0 |
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