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| 1 | FDG-PET/CT response evaluation during EGFR-TKI treatment in patients with NSCLC显示文摘Over recent years,[18F]-fluorodeoxyglucose positron emission tomography acquired together with low dose computed tomography(FDG-PET/CT)has proven its role as a staging modality in patients with non-small cell lung cancer(NSCLC).The purpose of this review was to present the evidence to use FDG-PET/CT for response evaluation in patients with NSCLC,treated with epidermal growth factor receptor(EGFR)-tyrosine kinase inhibitors(TKI).All published articles from 1November 2003 to 1 November 2013 reporting on 18FFDG-PET response evaluation during EGFR-TKI treatment in patients with NSCLC were collected.In total 7studies,including data of 210 patients were eligible for analyses.Our report shows that FDG-PET/CT responseduring EGFR-TKI therapy has potential in targeted treatment for NSCLC.FDG-PET/CT response is associated with clinical and radiologic response and with survival.Furthermore FDG-PET/CT response monitoring can be performed as early as 1-2 wk after initiation of EGFR-TKI treatment.Patients with substantial decrease of metabolic activity during EGFR-TKI treatment will probably benefit from continued treatment.If metabolic response does not occur within the first weeks of EGFR-TKI treatment,patients may be spared(further)unnecessary toxicity of ineffective treatment.Refining FDG-PET response criteria may help the clinician to decide on continuation or discontinuation of targeted treatment. | Matthijs H van Gool Tjeerd S Aukema Koen J Hartemink Renato A Valdés Olmos Houke M Klomp Harm van Tinteren | 2014 | World Journal of Radiology2014，6，7： | 8 |
| 2 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 3 | Mechanism and Kinetics of Strain Induced Precipitation of Nb (C, N) in Austenite显示文摘 | Dutta B Valdes E Sellars C M | 1992 | Acta Metallurgica1992，40，4： | 1 |
| 4 | Characterization and analysis of polymorphs by near-infrared spectrometry 显示文摘 | Blanco M Valdes D Bayod MS | 2004 | Analytica Chimica Acta2004，502，2： | 1 |
| 5 | A com- prehensive review of urologic complications in patients with dia- betes显示文摘 | Arrellano - Valdes F Urrutia - O-rio M ArroyoC etal | 2014 | Springerplus2014，11，3： | 1 |
| 6 | High Concen- tration Linear Fresnel Reflectors 显示文摘 | Abbas R Mufioz-Ant6n J Vald@s M | 2013 | Energy Conversion and Management2013，72，： | 1 |
| 7 | Effect of ozone treatment on surface properties of activated carbon显示文摘 | VALDES H SANcHEZ-POLO M RIVERA-UTRILLA J | 2002 | Langmuir2002，18，6： | 1 |
| 8 | Bikunin (uriary trypsin inhi- bitor) :structure,biological relevance,and measurement显示文摘 | Pugia M J Valdes R Jr Jortani SA | 2007 | Adv Clin Chem2007，44，： | 1 |
| 9 | Non- Frankla actinomycetes isolated from surface-sterilized roots of Casuarina equisetifolia fix nitrogen显示文摘 | Valdes M Perez N O Estrada-de Los Santos P | 2005 | App! Environ Microbiol2005，71，1： | 1 |
| 10 | Numeri cal Investigation of the Influence of Roughness on the Laminar Incompressible Fluid Flow through Annular Microchannels显示文摘 | Valdes J R Miana M J Pelegay J L | 2007 | International Journal of Heat and Mass Transfer2007，50，910： | 1 |
| 11 | Effect of ozone treatment on surface properties of activated carbon显示文摘 | VALDES H SANEHEZ M RIVERA J | 2002 | Langmuir2002，18，6： | 1 |
| 12 | Corporate governance, ownership structure and performance in Mexico显示文摘 | Martin-Reyna J M S Durim-Vezquez R Valdes A L | 2012 | International Business Research2012，5，： | 1 |
| 13 | A method to determine the economic cost of fouling of gas turbine compressors显示文摘 | MARTiN-ARAGON J VALDES M | 2014 | Applied Thermal Engineering2014，69，12： | 1 |
| 14 | Obesity, cigarette smoking, and telomere length in women显示文摘 | AM Valdes T Andrew JP Gardner M Kimura E Oelsner LF Cherkas A Aviv TD Spector | 2005 | The Lancet2005，，9486： | 1 |
| 15 | The role of the third-generation oral cephalosporin cefditoren pivoxil in the treatment of community-acquired infection in adults显示文摘 | Gimenez M J Gomez L M L Valdes L | 2005 | Rev Esp Quim ioter2005，18，3： | 1 |
| 16 | Effect of malate on mixed ruminal microorganism fermentation using the remen simulation technique 显示文摘 | Carro M D Lopez S Valdes C | 1999 | Animal Feed Science and Technology1999，79，4： | 1 |
| 17 | Allele frequencies at microsatellite loci: the stepwise mutation model revisited显示文摘 | Valdes A M | 1993 | Genetics1993，133，3： | 1 |
| 18 | Sand-rubber mixtures: Experiments and numerical simulations显示文摘 | VALDES J R EVANS T M | 2008 | Canadian Geoteehnieal Journal2008，45，4： | 1 |
| 19 | Mutation processes of simple-sequence repeat loci in human population显示文摘 | DI RIENZO A PETERSON A C GARZA J C VALDES A M SLATKIN M FREIMER N B | 1994 | Proceedings of the National Academy of Sciences USA1994，91，： | 1 |
| 20 | Absence of additioral cogni- tive impairment in schizophrenia patients during maintenance electro- convulsive therapy显示文摘 | Rami L Bemardo M Valdes M | 2004 | Schizar Bu112004，30，1： | 1 |
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