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| 1 | Epidural anaesthesia restores pancreatic microcirculation and decreases the severity of acute pancreatitis显示文摘瞄准:在尖锐胰腺炎(AP ) 期间在胰腺的微循环上调查硬膜上的麻醉(EA ) 的效果。方法:AP 被牛磺胆酸钠的注射导致进 Sprague-Dawley 老鼠的胰腺的管。认识到 EA,一根导管被介绍进在 T7 和 T9 之间的硬膜外腔, bupivacaine 被注射。Microcirculatory 流动被激光 Doppler flowmetry 测量。动脉的血气体分析被执行。在实验(<or=5 h ) 的结束,胰为组织学被移开。动物被划分成三个组:组织 1 (n=9 ) ,没有 EA 的 AP;组织 2 (n=4 ) ,没有 AP 的 EA;并且组织 3 (n=6 ) , AP 由 EA 对待。结果:在组 1,在 AP 以前的胰腺的微循环流动是 141+/- 39 个灌注单位(PU ) 。在 AP 以后,微循环流动显然减少了到 9+/- 6 PU (P<0.05 ) 。与基础过量开发的新陈代谢的酸中毒()-14+/-3 mmol/L。组织学揭示了广泛的浮肿和织物坏死。在组 2, EA 显著地没修改微循环流动。被仍然是未改变、组织学的分析显示出正常胰腺的织物。在组 3, AP 开始从 155+/-25 在微循环流动引起了重要减少到 11+/-7 PU (P<0.05 ) 。在 EA 的开始以后,微循环流动显然再增加了到 81+/-31 PU (P<0.05 ) 。是 -6+/-4 mmol/L,它与组 1 相比是显著地不同的(P<0.05 ) 。而且,组织学在组 1 在比那的组 3 在胰腺的组织揭示了不太广泛的浮肿和坏死。结论:AP 在胰以内引起了戏剧的微循环变化,与新陈代谢的酸中毒和织物坏死的开发。EA 允许微循环流动的部分恢复并且阻止了织物坏死和全身的复杂并发症的开发。因此, EA 应该被看作治疗学的选择阻止进化水肿到坏死的 AP。 | AlpDemirag CatherineMPastor PhilippeMorel NilgunGüvener GangMai ThierryBerney LeoHBühler CopinJean-Christophe Jean-LouisFrossard Andreas W.Sielenk mper Gang Mai | 2006 | World Journal of Gastroenterology2006，12，6： | 14 |
| 2 | Giant splenic artery aneurysm presenting with massive upper gastrointestinal bleeding:A case report and review of literature显示文摘BACKGROUND Splenic artery aneurysm(SAA)and pseudoaneurysm are rare vessel’s lesions.Pseudoaneurysm is often symptomatic and secondary to pancreatitis or trauma.True SAA is the most common aneurysm of visceral vessels.In contrast to pseudoaneurysm,SAA is usually asymptomatic until the rupture,with high mortality rate.The clinical onset of SSA’s rupture is a massive life-threatening bleeding with hemodynamic instability,usually into the free peritoneal space and more rarely into the gastrointestinal tract.CASE SUMMARY We describe the case of a 35-year-old male patient,with negative past medical history,who presented to the emergency department for massive upper gastrointestinal bleeding,severe anemia and hypotension.An esophagogastroduodenoscopy performed in emergency showed a gastric bulging in the greater curvature/posterior wall with a small erosion on its surface,with a visible vessel,but no active bleeding.Endoscopic injection therapy with cyanoacrylate glue was performed.Urgent contrast-enhanced computed tomography was carried out due to the clinical scenario and the unclear endoscopic aspect:The radiological examination showed a giant SAA which was adherent to posterior stomach wall,and some smaller aneurysms of the left gastric and ileocolic artery.Because of the high risk of a two-stage rupture of the giant SAA with dramatic outcome,the patient underwent immediate open surgery with aneurysmectomy,splenectomy and distal pancreatectomy with a good postoperative outcome.CONCLUSION The management of a ruptured giant SAA into the stomach can be successful with surgical approach. | Francesco Panzera Riccardo Inchingolo Marina Rizzi Assunta Biscaglia Maria Grazia Schievenin Emilia Tallarico Giancarlo Pacifico Beatrice Di Venere | 2020 | World Journal of Gastroenterology2020，26，22： | 4 |
| 3 | Trauma induced thyroid storm complicated by multiple organ failure显示文摘 | Mehmet Kanbay Aysegul Sengul Nilgn Gvener | 2005 | Chinese Medical Journal2005，，11： | 2 |
| 4 | Chk2 leaves the PML depot显示文摘 | Venere M Mochan TA Halazonetis TD | 2002 | Nat Cell Biol2002，4，11： | 1 |
| 5 | Embryonic stem cell-specific microRNAs promote induced pluripotency显示文摘 | Judson R L Babiarz J E Venere M | 2009 | Nat Bio-technol2009，27，5： | 1 |
| 6 | Increased expression of vascular endothelial growth factor receptor 1 correlates with VEGF and microvessel density in Philadelphia chromosome-negative myeloproliferative neoplasms显示文摘 | Boiocchi L Vener C Savi F | 2011 | J Clin Pathol2011，64，3： | 1 |
| 7 | Development of a multiplexed urine assay for prostate cancer diagnosis 显示文摘 | Vener T Derecho C Baden J | 2008 | Clin Chem2008，54，5： | 1 |
| 8 | Chsornosond characterization of the bonytongue Arapaima gigas ( Osteoglossiformes: Arapaimidae ) 显示文摘 | MARQUES D K VENERE P C JUNIOR P M G | 2006 | Neotropical Ichthyology2006，4，2： | 1 |
| 9 | Prognostic implications of the European consensus for grading of bone marrow fibrosis in chronic idiopathic myelofibrosis 显示文摘 | Vener C Fracchiolla NS Gianelli U | 2008 | Blood2008，111，4： | 1 |
| 10 | Syphilis treatment recommendations for Russian Federation显示文摘 | The Central Research Institute for Skin and Venereal Disease Moscow | 2001 | Int J STD AIDS2001，12，3： | 1 |
| 11 | Graph-based Cel ular Automata for Simulation of Surface Flows in Large Plains显示文摘 | Rinaldi P R Dalponte D D Venere M J | | 0，，05： | 1 |
| 12 | Glioma stem cell maintenance:the role of the Microenvironment显示文摘 | Heddleston JM Hitomi M Venere M | 2011 | Curr Pharm Des2011，17，23： | 1 |
| 13 | The effect of alendronate on res- orption of the alveolar bone foUowing tooth extraction显示文摘 | Altundal H G u vener O | 2004 | Int J Oral Maxillofal Surg2004，33，3： | 1 |
| 14 | Advanced operative office hysteroscopy without anaesthesis:analysis of 501 cases treated with electrode显示文摘 | Bettocchi S Ceci O Di Venere R | | 0，，09： | 1 |
| 15 | Effects of pre - and postharvest chitosan treatments to control storage grey mold of table grapes显示文摘 | Romanazzi G Nigro F Ippolito A Di Venere | 2002 | J Food Sci2002，67，： | 1 |
| 16 | A combined region growing and deformable model method for extraction of closed surfaces in 3D CT and MRI scans显示文摘 | FRESNO M VENERE M CLAUSSE A | 2009 | Computerized Medical Imaging and Graphics2009，33，5： | 1 |
| 17 | Embryonic stem cell-specific micrornas promote induced pluripotency 显示文摘 | Judson R L Babiarz J E Venere M | 2009 | Nat Biotechnol2009，27，5： | 1 |
| 18 | Mass Spectrometric Resolution of Reversible Protein Phosphorylation in Photosynthetic Membranes of Arabidopsis Thaliana显示文摘 | Vener AV Harms A Sussman MR | 2001 | J Biol Chem2001，276，： | 1 |
| 19 | Syphilis treatment recommendations for Russian Federation显示文摘 | The Central Research Institute for Skin and Venereal Disease Moscow | 2001 | Int J STD AIDS2001，12，3： | 1 |
| 20 | Rates of elemen-tary catalytic steps for different metal forms of the family II py-rophosphatase from Streptococcus gordonii显示文摘 | Zyryanov A B Vener A V Salminen A | 2004 | Biochemistry2004，43，4： | 1 |
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