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| 1 | Impact of protein kinase PKR in cell biology:from antiviral to antiproliferative action显示文摘 | Garcia M A Gil J Ventoso I | 2006 | Microbiol Mol Biol Rev2006，70，4： | 1 |
| 2 | Poliovirus 2A proteinase cleaves directly the eIF-4G snbnnit of eIF-4F com- plex显示文摘 | Ventoso I MacMillan SE Hershey JW | 1998 | FEBS Lett1998，435，1： | 1 |
| 3 | Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action显示文摘 | GARCIA M A GIL J VENTOSO I | 2006 | Microbiology and Molecular Biology Reviews2006，70，4： | 1 |
| 4 | Impact of protein kinase PKR in cell biology:from antiviral to antiproliferative action显示文摘 | Garcfa MA Gil J Ventoso I | 2006 | Microbiol Mol Biol Rev2006，70，4： | 1 |
| 5 | Impact of protein kinase PKR in cell biology:from antiviral to antiproliferative action显示文摘 | Garcia MA Gil J Ventoso I | 2006 | Microbiol Mol Biol Rev2006，70，4： | 1 |
| 6 | Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action 显示文摘 | Garcia M A Gil J Ventoso I | 2006 | Microbiol Mol Biol Rev2006，70，4： | 1 |
| 7 | Antiviral effect of the mammalian translation initiation factor 2α kinase GCN2 against RNA viruses显示文摘 | Berlanga J J Ventoso I Harding H P Deng J Ron D Sonenberg N Carrasco L de Haro C | 2006 | The EMBO Journal2006，25，： | 1 |
| 8 | Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action 显示文摘 | Garcia M A Gil J Ventoso I | 2006 | Microbiol Mol Biol Rev2006，70，： | 1 |
| 9 | Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action 显示文摘 | GARCIA M A GIL J VENTOSO I | 2006 | Microbiol Mot Biol Re2006，70，： | 1 |
| 10 | Management of Hepatocellular Carcinoma Recurrence After Liver Transplantation显示文摘 | A. Valdivieso J. Bustamante M. Gastaca J.G. Uriarte A. Ventoso P. Ruiz J.R. Fernandez I. Pijoan M. Testillano M.J. Suarez M. Montejo J. Ortiz de Urbina | 2010 | Transplantation Proceedings2010，，2： | 1 |
| 11 | Impact of protein kinase PKR in cell biology from antiviral to antiproliferative action 显示文摘 | Garcia MA Gil J Ventoso I | 2006 | Microbiol Mol Biol Rev2006，70，4： | 1 |
| 12 | Involvement of HIV-1 protease in virus-induced cell killing 显示文摘 | Ventoso I Navarro J Munoz MA | 2005 | Antiviral Res2005，66，1： | 1 |
| 13 | Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action 显示文摘 | Garcia MA Gil J Ventoso I | 2006 | Microbiol Mol Biol Rev2006，70，4： | 1 |
| 14 | Extensive translatome remodeling during ER stress response in mammalian cells显示文摘 | Ventoso I Kochetov A Montaner D | 2012 | PLoS One2012，7，35： | 1 |
| 15 | Extensive trans- latome remodeling during ER stress response in mammali- an cells显示文摘 | Ventoso I Kochetov A Montaner D | 2012 | PLoS One2012，7，35： | 1 |
| 16 | Translation Control by Protein Kinase R Restricts Minute Virus of Mice Infection:Role in Parvovirus Oncolysis显示文摘 | Ventoso I Berlanga J J Almendral J M | | 0，，10： | 1 |
| 17 | Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action 显示文摘 | Garcia MA Gil J Ventoso I | 2006 | Microbiol Mol Biol Rev2006，70，4： | 1 |
| 18 | Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action 显示文摘 | Garcia MA Gil J Ventoso I | 2006 | Microbiol Mol Biol Rev2006，70，4： | 1 |
| 19 | Early tacrolimus exposure does not impact long-term outcomes after liver transplantation显示文摘BACKGROUND Tacrolimus trough levels(TTL)during the first weeks after liver transplantation(LT)have been related with long-term renal function and hepatocellular carcinoma recurrence.Nevertheless,the significance of trough levels of tacrolimus during the early post-transplant period for the long-term outcome is under debate AIM To evaluate the effect of TTL during the first month on the long-term outcomes after LT.METHODS One hundred fifty-five LT recipients treated de novo with once-daily tacrolimus were retrospectively studied.Patients with repeated LT or combined transplantation were excluded as well as those who presented renal dysfunction prior to transplantation and/or those who needed induction therapy.Patients were classified into 2 groups according to their mean TTL within the first month after transplantation:≤10(n=98)and>10 ng/mL(n=57).Multivariate analyses were performed to assess risk factors for patient mortality.RESULTS Mean levels within the first month post-transplant were 7.4±1.7 and 12.6±2.2 ng/mL in the≤10 and>10 groups,respectively.Donor age was higher in the high TTL group 62.9±16.8 years vs 45.7±17.5 years(P=0.002)whilst mycophenolate-mofetil was more frequently used in the low TTL group 32.7%vs 15.8%(P=0.02).Recipient features were generally similar across groups.After a median follow-up of 52.8 mo(range 2.8-81.1),no significant differences were observed in:Mean estimated glomerular filtration rate(P=0.69),hepatocellular carcinoma recurrence(P=0.44),de novo tumors(P=0.77),new-onset diabetes(P=0.13),or biopsy-proven acute rejection rate(12.2%and 8.8%,respectively;P=0.50).Eighteen patients died during the follow-up and were evenly distributed across groups(P=0.83).Five-year patient survival was 90.5%and 84.9%,respectively(P=0.44),while 5-year graft survival was 88.2%and 80.8%,respectively(P=0.42).Early TTL was not an independent factor for patient mortality in multivariate analyses.CONCLUSION Differences in tacrolimus levels restricted to the first month after transplant did not result in significant differences in long-term outcomes of LT recipients. | Mikel Gastaca Patricia Ruiz Javier Bustamante Lorea Martinez-Indart Alberto Ventoso JoséRamón Fernandez Ibone Palomares Mikel Prieto Milagros Testillano Patricia Salvador Maria Senosiain Maria Jesus Suárez Andres Valdivieso | 2021 | World Journal of Hepatology2021，13，3： | 0 |
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