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| 1 | COVID-19 and liver injury: An ongoing challenge显示文摘The new coronavirus severe acute respiratory syndrome coronavirus 2(SARSCoV-2)was identified in December 2019,in Wuhan,China.The virus was rapidly spread worldwide,causing coronavirus disease 2019(COVID-19)pandemic.Although COVID-19 is presented,usually,with typical respiratory symptoms(i.e.,dyspnea,cough)and fever,extrapulmonary manifestations are also encountered.Liver injury is a common feature in patients with COVID-19 and ranges from mild and temporary elevation of liver enzymes to severe liver injury and,even,acute liver failure.The pathogenesis of liver damage is not clearly defined;multiple mechanisms contribute to liver disorder,including direct cytopathic viral effect,cytokine storm and immune-mediated hepatitis,hypoxic injury,and druginduced liver toxicity.Patients with underlying chronic liver disease(i.e.,cirrhosis,non-alcoholic fatty liver disease,alcohol-related liver disease,hepatocellular carcinoma,etc.)may have greater risk to develop both severe COVID-19 and further liver deterioration,and,as a consequence,certain issues should be considered during disease management.The aim of this review is to present the prevalence,clinical manifestation and pathophysiological mechanisms of liver injury in patients with SARS-CoV-2 infection.Moreover,we overview the association between chronic liver disease and SARS-CoV-2 infection and we briefly discuss the management of liver injury during COVID-19. | Ioanna Papagiouvanni Serafeim-Chrysovalantis Kotoulas Athanasia Pataka Dionisios G Spyratos Konstantinos Porpodis Afroditi K Boutou Georgios Papagiouvannis Ioanna Grigoriou Christos Vettas Ioannis Goulis | 2023 | World Journal of Gastroenterology2023，29，2： | 2 |
| 2 | Location choices under quality uncertainty 显示文摘 | Christou C Vettas N | 2005 | Mathematical Social Sciences2005，50，3： | 1 |
| 3 | Price competition in a differentiated products duopoly under network effects显示文摘 | Griva K Vettas N | 2011 | Information Economics and Policy2011，23，1： | 1 |
| 4 | Effect of moderate physical activity on plasma leptin concentration in humans 显示文摘 | Dirlewanger M Di Vetta V Ginsti V | 1999 | Eur J Appl Physiol1999，79，： | 1 |
| 5 | Price competition in a differentiated products duopoly under network effects 显示文摘 | Griva K Vettas N | 2011 | Information Economics and Policy2011，23，1： | 1 |
| 6 | On Clusterings : Good, Bad and Spectral 显示文摘 | Kannan R Vempalat S Vetta A | 2004 | Journal of the ACM2004，51，3： | 1 |
| 7 | Effect of moderate physical activity on plasma leptin concentration in humans显示文摘 | Di Vetta V Giusti V | 1999 | Eur J Appl Physiol Occup Physiol1999，79，4： | 1 |
| 8 | Baroreflex sensitivityin the elderly with silent myocardial ischemia显示文摘 | Piccirillo Q Vetta F Ronzoni S | 1997 | ArchGerontol Geriatr1997，26，1： | 1 |
| 9 | On clusterings:good,bad,and spectral显示文摘 | Kannan R Vempala S Vetta A | 2004 | Journal of the ACM2004，51，3： | 1 |
| 10 | Optimal dynamic pricing with inventories显示文摘 | Varma G D Vettas N | 2001 | Economics Letters2001，72，： | 1 |
| 11 | Demand and Supply in New Markets:Diffusion with Bilateral Learning显示文摘 | VETTAS K | 1998 | Rand Journal of Economics1998，，29： | 1 |
| 12 | On clusterings显示文摘 | Ravi Kannan Santosh Vempala Adrian Vetta | 2004 | Journal of the ACM (JACM)2004，，3： | 1 |
| 13 | Hyperinsulinaemia,regional adipose tissue distribution and left ventricular mass in normotensive,elderly,obese subjects显示文摘 | Vetta F Cicconetti P Ronzoni | 1998 | Eur Heart J1998，19，： | 1 |
| 14 | On informative advertising and product differentiation 显示文摘 | Christou O Vettas N | 2008 | International Journal of Industrial Organization2008，26，1： | 1 |
| 15 | On clusterings: Good, bad and spectral显示文摘 | Kannan R Vempala S Vetta A | 2004 | Journal of the ACM2004，51，3： | 1 |
| 16 | On Entry, Exit, and Coordination with Mixed Strategies 显示文摘 | Vettas N | 2000 | European Economic Review2000，44，8： | 1 |
| 17 | Effect of aerobic training on the cognitive perfor- mance of elderly patients with senile dementia of alzheimer type显示文摘 | Palleschi L Vetta F De Gennaro E | 1996 | Archives of Geron- tology and Geriatrics1996，，22： | 1 |
| 18 | Hyperinsulinaemia,regional adiposetissue distribution and left ventricular mass in normotensive,elderly,obese sub-jects 显示文摘 | Vetta F Cicconetti P Ronzonis M | 1998 | Eur Heart J1998，19，2： | 1 |
| 19 | Predicting direct protein interactions from affinity purification mass spectrometry data 显示文摘 | Kim E D H Sabharwal A Vetta A R | 2010 | Algorithms for Molecular Biology2010，5，： | 1 |
| 20 | Price competition in a differentiated products duopoly under network effects 显示文摘 | Griva K Vettas N | 2010 | Information Economics and Policy2010，23，1： | 1 |
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