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2篇 您的检索式:作者名="Vicky Hunt"
    题名 作者 年代 出处 被引量
1Infection does not increase long-term mortality in patients with acute severe alcoholic hepatitis treated with corticosteroids显示文摘AIM To determine whether infection in patients with acute severe alcoholic hepatitis(AAH) treated with corticosteroids is associated with increased mortality.METHODS Consecutive patients with AAH were treated with steroids and recruited to the study. Clinically relevant infections(body temperature > 38 ℃ or < 36 ℃ for more than 4 h, ascitic neutrophil count > 0.25 ×109/L, consolidation on chest radiograph or clinically relevant positive microbiological culture of bodily fluid) were recorded prospectively. Clinical and laboratory parameters were recorded and survival at 90 d and 6 mo was determined. Univariate analysis of factors associated with 90-d mortality was performed and significant variables included in a multivariate analysis.RESULTS Seventy-two patients were included in the final analysis(mean age 47.9 years, 26% female, mean discriminant function 53.0). Overall mortality in the group occurred in 15(21%), 23(32%) and 31(43%) at day 28, day 90 and 1 year respectively. 36(50%) had a clinically relevant infection during their hospitalisation(23 after initiation of steroids). The median time to development of incident infection after commencement of steroids was 10 d. The commonest site of infection was ascites(31%) and bacteraemia(31%) followed by urinary tract(19%) and respiratory tract(8%). Forty-one separate organisms were isolated in 33 patients; the most frequent genus was Escherichia(22%) and Enterococcus(20%). Infection was not associated with 90-d or 1 year mortality but was associated with higher creatinine, model for end-stage liver disease and Lille score. Baseline urea was the only independent predictor of 90-d mortality.CONCLUSION Clinically relevant infections are common in patients with AAH but are not associated with increased 90-d or 1 year mortality.Ashwin D Dhanda Ashish Sinha Vicky Hunt Sarah Saleem Matthew E Cramp Peter L Collins 2017World Journal of Gastroenterology2017,23,11:1
2Improving Hypertension Control in Diabetes显示文摘Mark E. Lindsay Michael J. Hovan James R. Deming Vicki L. Hunt Stephanie G. Witwer Leslie A. Fedraw Jerry W. Sayre Marc R. Matthews Valerie W. Halling Robert C. Graber Rachel L. Martin Jacqueline C. Wright Jane F. Myers Reinold H. Plate Sonja M. Hruska Ka 2013American Journal of Medical Quality2013,,5:1
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