|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 诊断性试验和策略的证据质量和推荐强度的分级显示文摘GRADE系统能对诊断性试验或策略的证据质量和推荐强度进行分级。本文旨在阐释在此过程中如何考虑患者的重要结局, | Holger J Schünemann Andrew D Oxman Jan Brozek Paul Glasziou Roman Jaeschke Gunn E Vist John W Williams Jr Regina Kunz Jonathan Craig Victor M Montori Patrick Bossuyt Gordon H Guyatt 李晓 黄程 陈耀龙 李幼平 | 2009 | 中国循证医学杂志2009，9，5： | 7 |
| 2 | Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency显示文摘Pluripotency,一个细胞的能力区分并且产生所有胚胎的系,定义象胚胎的茎(ES ) 那样的哺乳动物的细胞类型的一个小数字细胞。当它通常被保持了时,那 pluripotency 是 transcriptional 的产品激活并且维持关键干细胞基因的表达式的规章的网络,积累的证据在建立并且保卫 ES 房间的 pluripotency 为 epigenetic 进程正在指向一个关键角色,象维持区分的房间类型的身份一样。以便更好在 pluripotency 理解 epigenetic 机制的角色,我们检验了在经历区别进一个 mesendodermal 系的人的 ES 房间(hESCs ) 染色体宽的染色质修正的动力学。我们发现在倡导者的染色质修正在区别期间仍然保持大部分不变,除了在在在 H3K27 的 acetylation 和 methylation 之间的一个动态开关标记在基因表示的激活和 silencing 之间的转变的倡导者的一个小数字,建议在在大多数差别上的房间命运承诺的一个层次表示了基因。我们也在 50 000 潜在的 enhancers 上印射,并且在染色质修正,特别 H3K4me1 和 H3K27ac 观察了大得多的动力学,它与他们的潜在的目标基因的表示相关。这些 enhancers 的进一步的分析揭示了 pluripotency 和可以在 hESCs 授与发展胜任的一个平衡状态的一口染色质签名陈述语气的潜在地关键的 transcriptional 管理者。我们的结果提供在定义 enhancers 和 pluripotency 支持染色质修正的角色的新证据。 | R David Hawkins Gary C Hon Chuhu Yang Jessica E Antosiewicz-Bourget Leonard K Lee Que-Minh Ngo Sarit Klugman Keith A Ching Lee E Edsall Zhen Ye Samantha Kuan Pengzhi Yu Hui Liu Xinmin Zhang Roland D Green Victor V Lobanenkov Ron Stewart James A Thomson Bing Ren | 2011 | Cell Research2011，21，10： | 6 |
| 3 | Central pontinemyelinolysis: a hitherto undescribed disease occurring in alcoholic and malnourished patients 显示文摘 | Adams R D Victor M Mancall E L | 1959 | AMA Arch Neurol Psychiatry1959，81，4： | 1 |
| 4 | Dynamics of shock dispersion and interactions in supersonic freestreams with counterflowing jets显示文摘 | Endwell O D Victor E P Wang Ten S | 2009 | AIAA Journal2009，47，6： | 1 |
| 5 | Morphological Control for High Performance, Solution-Processed Planar Herterojunc-tion Perovskite Solar Cells显示文摘 | Giles E Victor M B Pablo D | 2014 | Advanced Functional Materials2014，24，1： | 1 |
| 6 | Smooth - muscle physiology显示文摘 | Philippe E Victor K John D | 1996 | Urol Clin NorthAm1996，23，： | 1 |
| 7 | Corin gene minor allele defined by 2 missense mutations is common in Blackes and associationed with high blood pressure and hypertension显示文摘 | Dries D L Victor R G Rame J E | 2005 | Circulation2005，112，16： | 1 |
| 8 | Effect of irrigation frequency on turf quality, shoot density, and root length density of five bentgrass cultivar显示文摘 | Jordan J E White R H Victor D M Hale | 2003 | Crop Science2003，43，1： | 1 |
| 9 | Molecular biology of the rennin angiotensin system显示文摘 | Victor J Dzau Burt D W Richard E Pratt | | 0，，04： | 1 |
| 10 | Cardiac steatosis and left ventricular hypertrophy in patients with generalized lipodystrophy as determined by magnetic resonance spectroscopy and imaging显示文摘 | Nelson M D Victor R G Szczepaniak E W | 2013 | Am J Cardiol2013，112，7： | 1 |
| 11 | Treatment Ontcome with radiation therapy after breast augmentation or reconstructionin patients with primary breast can cer 显示文摘 | Victor S J Brown D M Horwitz E M | 1998 | Cancer1998，82，7： | 1 |
| 12 | SPINS:Security Protocols for Sensor Networks显示文摘 | Adrian Perrig Robert Szewczyk Tygar J D Victor Wen and Culler David E | 2002 | Wireless Networks2002，，8： | 1 |
| 13 | Smooth muscle physiology显示文摘 | Philippe E Zimmem Victor K Lin John D | 1996 | Uro Chin North Am1996，23，： | 1 |
| 14 | Heat capacity and heat of dissociation of methane hydrates显示文摘 | Rueff R M Sloan E D Victor F | 1988 | Yesavage AIChE Journal1988，34，9： | 1 |
| 15 | Design of Green Engineered Cementitious Composites for Improved Sustainability显示文摘 | Lepech Michael D Li Victor C Robertson Richard E Keoleian Gregory A | 2008 | ACI Materials Journal2008，，6： | 1 |
| 16 | The determined chaos in disturbed by temperature dynamic systems with gyros显示文摘 | Victor E D Vladimir M P | 2003 | IEEE2003，，： | 1 |
| 17 | Enzymatic control of nonstructural carbohydrate concentrations in stems and panicles of sorghum 显示文摘 | Tarpley L Lingle S E Victor D M | 1994 | Crop Science1994，34，： | 1 |
| 18 | Women's knowledge of congenital cytomegalovirus: results from the 2005 HealthStyles survey显示文摘 | Ross D S Victor M Sumartojo E | 2008 | J Women'' s Health ( Larchmt)2008，17，： | 1 |
| 19 | Neuropathology of experimental vitamin B12 deficiency in monkeys显示文摘 | Agamanolis D P Chester E M Victor M | 1976 | Neurology1976，26，10： | 1 |
| 20 | Design of Green Engineered Cementitious Composites for Improved Sustainability显示文摘 | Lepech Michael D Li Victor C Robertson Richard E Keoleian Gregory A | 2008 | ACI Materials Journal2008，，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员