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| 1 | C-Reactive protein predicts short-term mortality in patients with cirrhosis显示文摘 | Jean-Paul Cervoni Thierry Thévenot Delphine Weil Emilie Muel Olivier Barbot Frances Sheppard Elisabeth Monnet Vincent Di Martino | 2012 | Journal of Hepatology2012，，6： | 2 |
| 2 | An uncommon cause of stroke in young adults显示文摘 | Bastiaan R Vincent TH | 1999 | Arch Neurol1999，56，： | 1 |
| 3 | Characterization and role of intra-hepatic regulatory T cells in chronic hepatitis C pathogenesis显示文摘 | Nathalie Sturm Marie-Ange Thélu Xavier Camous Guéorgui Dimitrov Muhammad Ramzan Tania Dufeu-Duchesne Paula Bonorino Christiane Guillermet Elisabeth Brambilla Philippe Arvers Martine Pernollet Vincent Leroy Jean-Pierre Zarski Patrice N. Marche Evelyne Jouv | 2010 | Journal of Hepatology2010，，1： | 1 |
| 4 | Sexual Selection and the Potential Reproductive Rates of Males and Females显示文摘 | Cluttoobrock TH Vincent ACJ | | 0，，： | 1 |
| 5 | Genetic factors for differentiated thyroid cancer in French Polynesia:new candidate loci显示文摘Background:Populations of French Polynesia(FP),where France performed atmospheric tests between 1966 and 1974,experience a high incidence of differentiated thyroid cancer(DTC).However,up to now,no sufficiently large study of DTC genetic factors in this population has been performed to reach definitive conclusion.This research aimed to analyze the genetic factors of DTC risk among the native FP populations.Methods:We analyzed more than 300000 single nucleotide polymorphisms(SNPs)genotyped in 283 DTC cases and 418 matched controls born in FP,most being younger than 15 years old at the time of the first nuclear tests.We analyzed the genetic profile of our cohort to identify population subgroups.We then completed a genome-wide analysis study on the whole population.Results:We identified a specific genetic structure in the FP population reflecting admixture from Asian and European populations.We identified three regions associated with increased DTC risk at 6q24.3,10p12.2,and 17q21.32.The lead SNPs at these loci showed respective p-values of 1.66×10^(−7),2.39×10^(−7),and 7.19×10^(−7) and corresponding odds ratios of 2.02,1.89,and 2.37.Conclusion:Our study results suggest a role of the loci 6q24.3,10p12.2 and 17q21.32 in DTC risk.However,a whole genome sequencing approach would be better suited to characterize these factors than genotyping with microarray chip designed for the Caucasian population.Moreover,the functional impact of these three new loci needs to be further explored and validated. | Monia Zidane Marc Haber Thérèse Truong Frédérique Rachédi Catherine Ory Sylvie Chevillard Hélène Blanché Robert Olaso Anne Boland Éric Conte Mojgan Karimi Yan Ren Constance Xhaard Vincent Souchard Jacques Gardon Marc Taquet André Bouville Jean-François Deleuze Vladimir Drozdovitch Florent de Vathaire Jean-Baptiste Cazier | 2023 | Precision Clinical Medicine2023，6，2： | 0 |
| 6 | AB093.Ocular tissues bank for vision health research显示文摘Background:This infrastructure delivers biological material necessary for several research projects to Vision Health Research Network investigators(VHRN).Methods:Héma-Québec is the organism in charge obtaining consent and retrieving donor eyes for patient treatment or for research.In Quebec City,donor eyes are sent to the eye bank of the“Centre Universitaire d’Ophtalmologie”(CUO)of Saint-Sacrement hospital.Technicians at the eye bank evaluate the quality of the tissues.Those unfit for graft are transferred to the infrastructure where the coordinator encodes samples prior to their distribution.Results:Between 2013 and 2017,27 fundamental investigators,clinical investigators and collaborators supported by 60 students,trainees and laboratory assistants used this infrastructure to move forward their projects.Since 2013,results from those projects generated 21 scientific publications and 232 presentations.The infrastructure helped VHRN investigators obtain near 4 million dollars in grants from many organisms(CIHR,NSERC,Foundations,etc.).These grants allowed recruitment and formation of highly qualified personnel.Last year(April 2016 to March 2017),189 corneas and 23 eyes transited through the infrastructure.Conclusions:This infrastructure is available for all investigators that are members of the VHRN.Many original projects have been elaborated thanks to the human ocular tissues provided by this infrastructure.These projects will advance our knowledge in vision health.A better understanding of eye functions will lead to new treatments for eye diseases. | Kim Santerre Mathieu Thériault Sylvain Chemtob Lucie Germain Claude Giasson Sylvain Guérin Solange Landreville Patrick JRochette Christian Rochette Mike Sapieha Élodie Boisselier Vincent Pernet Stéphanie Proulx | 2018 | Annals of Eye Science2018，，1： | 0 |
| 7 | Alfapump®implantable device in management of refractory ascites:An update显示文摘Refractory ascites(RA)is a frequent and life-threatening complication of cirrhosis.In selected patients with RA,transjugular intrahepatic portosystemic shunt(TIPS)placement and liver transplantation(LT)are currently considered the best therapeutic alternatives to repeated large volume paracentesis.In patients with a contraindication to TIPS or LT,the alfapump®system(Sequana Medical,Ghent,Belgium)has been developed to reduce the need for iterative paracentesis,and consequently to improve the quality of life and nutritional status.We report here recent data on technical progress made since the first implantation,the efficacy and tolerance of the device,the position of the pump in the therapeutic arsenal for refractory ascites,and the grey areas that remain to be clarified regarding the optimal selection of patients who are potential candidates for this treatment. | Delphine Weil-Verhoeven Vincent Di Martino Guido Stirnimann Jean Paul Cervoni Eric Nguyen-Khac Thierry Thévenot | 2022 | World Journal of Hepatology2022，14，7： | 0 |
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