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| 1 | A complete compilation of matrix metalloproteinase expression in human malignant gliomas显示文摘Glioblastomas are characterized by an aggressive local growth pattern, a marked degree of invasiveness and poor prognosis. Tumor invasiveness is facilitated by the increased activity of proteolytic enzymes which are involved in destruction of the extracellular matrix of the surrounding healthy brain tissue. Elevated levels of matrix metalloproteinases(MMPs) were found in glioblastoma(GBM) cell-lines, as well as in GBM biopsies as compared with low-grade astrocytoma(LGA) and normal brain samples, indicating a role in malignant progression. A careful review of the available literature revealed that both the expression and role of several of the 23 human MMP proteins is controversely discussed and for some there are no data available at all. We therefore screened a panel of 15 LGA and 15 GBM biopsy samples for those MMPs for which there is either no, very limited or even contradictory dataavailable. Hence, this is the first complete compilation of the expression pattern of all 23 human MMPs in astrocytic tumors. This study will support a better understanding of the specific expression patterns and interaction of proteolytic enzymes in malignant human glioma and may provide additional starting points for targeted patient therapy. | Carsten Hagemann Jelena Anacker Ralf-Ingo Ernestus Giles H Vince | 2012 | World Journal of Clinical Oncology2012，3，5： | 18 |
| 2 | 葡萄糖转运蛋白-1和-3在缺氧缺血性脑损伤新生大鼠脑内表达的变化及意义显示文摘目的探讨缺氧缺血性脑损伤(H IBD)后脑内负责葡萄糖转运的两个重要蛋白质葡萄糖转运蛋白-1(GLUT-1)与葡萄糖转运蛋白-3(GLUT-3)表达的变化,揭示H IBD后脑内能量衰竭的发病机制。方法将30只7日龄W istar大鼠随机分为正常对照组(n=5)、假手术对照组(n=5)和H IBD组(n=20)。H IBD组大鼠模型的制备参照R ice。方法结扎右侧颈总动脉后8%低氧暴露1 h。假手术对照组只分离右侧颈动脉,不予结扎和缺氧。缺氧缺血后1,3,5,10 d各处死5只H IBD大鼠,免疫组化方法检测大鼠脑内GLUT1及GLUT3表达,并与对照组和假手术组比较。结果正常新生大鼠脑内微血管即可见GLUT1表达。H IBD后1 d,缺血侧半球GLUT1表达略有增加,3 d达高峰,至5 d时仍高于正常,10 d基本恢复正常水平。H IBD后1 d,GLUT3表达无明显变化,3 d时GLUT3表达已明显减少,5 d时进一步减少,10 d时仍显著低于对照组。GLUT3表达减少最显著的部位为海马CA1区。结论H IBD后脑内GLUT1和GLUT3的表达异常可导致脑能量代谢途径改变,加重缺氧缺血后神经元的损伤及影响损伤神经元的修复。 | 辛颖 Vince RUSSO George WERTHER | 2005 | 中国当代儿科杂志2005，7，6： | 4 |
| 3 | Androgen receptors are expressed in a variety of human fetal extragenital tissues: an immunohistochemical study显示文摘瞄准:在开发人的胚胎的额外的生殖器的纸巾调查雄激素受体的表示。方法:用免疫组织化学,我们在第一个三个月(8-12 星期怀孕期) 的嵌入石蜡的织物节的额外的生殖器的纸巾调查了雄激素受体(AR ) 的分发人的胚胎。性被 polymerized 链反应决定。结果:在在在怀孕期的任何阶段的男、女的胚胎的 AR 的表示和分发没有差别。AR 表示在胸腺腺被看见。肺的支气管的上皮显示出与包围基质的强烈积极染色否定。而且,为雄激素受体的积极染色在包围纸巾与一些积极房间在针的绳索被展出。心脏的阀门也显示出强壮的积极染色但是与包围心肌的微弱反应。在肾没有染色,肾,肝或肠。结论:这研究表明反应 AR 蛋白质是的那免疫在许多人第一三个月在场胎儿的纸巾和表演为影响纸巾的雄激素的潜力,它主要没被认为是雄激素依赖者。而且,它暗示那雄激素可能充当一个营养的因素并且影响这些机关而非简单地的早发展性区别。 | Yasmin Sajjad Siobhan Quenby Paul Nickson David Iwan Lewis-Jones Gill Vince | 2007 | Asian Journal of Andrology2007，9，6： | 4 |
| 4 | Scalable nanomanufacturing of surfactant-free carbon nanotube inks for spray coatings with high conductivity显示文摘Spray-coated carbon nanotube films offer a simple and printable solution for fabricating low cost, lightweight, and flexible thin-film electronics. However, current nanotube spray inks require either a disruptive surfactant or destructive surface functionalization to stabilize dispersions at the cost of the electrical properties of the deposited film. We demonstrate that high-purity few-walled carbon nanotubes may be stabilized in isopropanol after surface functionalization and that optimizing the ink stability dramatically enhances the conductivity of subsequent spray-coated thin films. We consequently report a surfactant-free carbon nanotube ink for spray-coated thin films with conductivities reaching 2,100 S/cm. Zeta-potential measurements, used to quantify the nanotube ink dispersion quality, directly demonstrate a positive correlation with the spray- coated film conductivity, which is the key metric for high-performance printed electronics. | Colin Preston Da Song Jaiqi Dai Zois Tsinas John Bavier John Cumings Vince Ballarotto Liangbing Hu | 2015 | Nano Research2015，8，7： | 4 |
| 5 | Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer显示文摘 | Qingshan Chang Yadong Zhang Kevin J. Beezhold Deepak Bhatia Hongwen Zhao Jianguo Chen Vince Castranova Xianglin Shi Fei Chen | 2008 | Journal of Hepatology2008，，2： | 3 |
| 6 | 地质学家震源机制解入门显示文摘本文的目的是帮助学生提高识别和解释"海滩球"图(地震学家推导的矩张量几何形状的图形表示)的技能。笔者把有关获取矩张量过程的大部分定量细节描述留给地震学教程或文献中讲述。然而,笔者发现有关如何手工获得震源机制解(FMS)的一些知识对学生很有用,因此整个过程并不具有多少黑箱艺术。 | Vince Cronin 李万金 李永华 吕春来 | 2015 | 世界地震译丛2015，46，1： | 3 |
| 7 | 有机硅在洗去型护发产品中的应用显示文摘 | Brett Moss Vince Ungvary Sabrina Marchioretto | 2005 | 日用化学品科学2005，28，9： | 3 |
| 8 | Managing the post–liver transplantation anastomotic biliary stricture: multiple plastic versus metal stents: a systematic review显示文摘 | Dina Kao Sergio Zepeda-Gomez Puneeta Tandon Vince G. Bain | 2013 | Gastrointestinal Endoscopy2013，，5： | 2 |
| 9 | A comparison of cardiovascular risk indices in patients with polycystic ovary syndrome with and without coexisting nonalcoholic fatty liver disease显示文摘 | Alison J. Dawson Thozhukat Sathyapalan Jacqueline A. J. Smithson Rebecca V. Vince Anne‐Marie Coady Ramzi Ajjan Eric S. Kilpatrick Stephen L. Atkin | 2014 | Clin Endocrinol2014，，6： | 2 |
| 10 | Interpreting the Mechanisms of Continuous Renal Replacement Therapy in Sepsis: The Peak Concentration Hypothesis显示文摘 | ClaudioRonco CiroTetta FilippoMariano Mary LouWratten MonicaBonello ValeriaBordoni XimenaCardona PaolaInguaggiato LidiaPilotto VinceD’Intini RinaldoBellomo | 2003 | Artificial Organs2003，，9： | 1 |
| 11 | The radiologic prevalence of patellofemoral osteoporosis显示文摘 | Davies A P Vince A S Shepstone L | 2002 | Clin Orthop Relat Res2002，402，： | 1 |
| 12 | Real-time remedy 显示文摘 | VINCE P | 2001 | Traffic Technology International2001，7，6： | 1 |
| 13 | An epoch debate 显示文摘 | VINCE G | 2011 | Science2011，334，： | 1 |
| 14 | Follicular fluid concentrations of interleukin-12 and interleukin8 in IVF cycles显示文摘 | Gazvani MR Bates M Vince G | 2000 | Fertil Steril2000，74，5： | 1 |
| 15 | Internal rotation of the tibial component is frequent in stiff total knee arthroplasty显示文摘 | Bédard M Vince KG Redfern J | 2011 | 469(8):2346-23552011，469，8： | 1 |
| 16 | Manufacturing in Blow Molding: Time Reduction and Part Quality Improvement显示文摘 | ATTAR A BHUIYAN N THOMSON Vince | 2008 | Journal of Materials ProcessingTechnology2008，204，13： | 1 |
| 17 | The radiologic prevalence of patellofemoral osteoarthritis 显示文摘 | Davies AP Vince AS Shepstone L | 2002 | Clin Orthop Relat Res2002，，402： | 1 |
| 18 | Unstable tandem repeats in promoters confer transcriptional evolvability显示文摘 | Vinces M D Legendre M Caldara M | 2009 | Science2009，324，： | 1 |
| 19 | Star chromdtic number显示文摘 | Vince A | 1988 | J Graph Theory1988，12，： | 1 |
| 20 | Localization of IL-4 and IL-4 receptors in the human term placenta,decidua and amniochorionic membranes显示文摘 | De Moraes-Pinto MI Vince GS Flanagan BF | 1997 | Immunology1997，90，1： | 1 |
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