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| 1 | 亚太地区炎症性肠病处理共识意见(一)显示文摘虽然目前亚太地区尚无炎症性肠病(IBD)的大规模流行病学资料,但一系列研究显示其发病率和患病率呈上升趋势,与西方国家相比仍呈滞后现象,溃疡性结肠炎(UC)的发病率仍较克罗恩病(CD)高。除地域差异外,在一些多民族国家中,IBD尚可见种族差异。亚太地区IBD的遗传背景有异于西方国家,如据报道该地区CD患者未检出NOD2/CARD15变异。一般而言,该地区IBD患者的临床过程似不如西方国家严重。亚太地区IBD的诊断存在一些特殊问题。如缺乏IBD诊断金标准,存在多种小肠结肠炎,与IBD临床表现相似,使鉴别诊断特别困难。迄今为止,亚太地区IBD的诊断标准多采用西方国家的诊断标准。诊断必须逐步排除非IBD的小肠结肠炎,确诊应有典型的组织学表现,某些患者需借助随访和诊断性治疗才能确诊。进一步研究IBD发病机制将有助于开发更好的诊断标记物。亚太地区IBD的治疗亦存在特殊问题。由于诊断困难,IBD患者常未能及时接受适当的药物治疗,但该地区仍广泛采用药物治疗方案。结合西方指南和本地经验可制定类似的处理原则,以利诱导缓解和维持缓解。提倡逐级使用基于病变范围、活动性和严重度的阶梯式治疗方案,对不同病例采用综合性、个体化的方法。随着对IBD发病机制和亚太地区IBD独特性的深入理解,合理、实用的药物治疗指南和应用生物制剂治疗将改善该地区IBD的治疗前景。 | 欧阳钦 Rakesh Tandon KL Goh 潘国宗 KM Fock Claudio Fiocchi SK Lam 萧树东 张虎 梁红亮 王玉芳 | 2006 | 胃肠病学2006，11，4： | 123 |
| 2 | 亚太地区炎症性肠病处理共识意见(二)显示文摘 | 欧阳钦 Rakesh Tandon KL Goh 潘国宗 KM Fock Claudio Fiocchi SK Lam 萧树东 张虎(翻译) 梁红亮(翻译) 王玉芳(翻译) 欧阳钦(审校) | 2006 | 胃肠病学2006，11，5： | 47 |
| 3 | DSM-5中关于精神分裂症诊断标准修改的建议显示文摘目前对于精神分裂症的概念源自19世纪末埃米尔.克雷丕林对早发性痴呆的阐述及20世纪早、中期尤金.布洛鲁勒和柯特.施耐德的贡献。克雷丕林主要是根据病程(逐步恶化)和结局(痴呆或"精神迟钝")识别出早发性痴呆。尤金.布鲁勒重新命名为"精神分裂症", | Rajiv TANDON | 2011 | 上海精神医学2011，23，2： | 21 |
| 4 | Systematic review of nutrition screening and assessment in inflammatory bowel disease显示文摘BACKGROUND Malnutrition is prevalent in inflammatory bowel disease (IBD). Multiple nutrition screening (NST) and assessment tools (NAT) have been developed for general populations, but the evidence in patients with IBD remains unclear. AIM To systematically review the prevalence of abnormalities on NSTs and NATs, whether NSTs are associated with NATs, and whether they predict clinical outcomes in patients with IBD. METHODS Comprehensive searches performed in Medline, CINAHL Plus and PubMed. Included: English language studies correlating NSTs with NATs or NSTs/NATs with clinical outcomes in IBD. Excluded: Review articles/case studies;use of body mass index/laboratory values as sole NST/NAT;age<16. RESULTS Of 16 studies and 1618 patients were included, 72% Crohn’s disease and 28% ulcerative colitis. Four NSTs (the Malnutrition Universal Screening Tool, Malnutrition Inflammation Risk Tool (MIRT), Saskatchewan Inflammatory Bowel Disease Nutrition Risk Tool (SaskIBD-NRT) and Nutrition Risk Screening 2002 (NRS-2002) were significantly associated with nutritional assessment measures of sarcopenia and the Subjective Global Assessment (SGA). Three NSTs (MIRT, NRS-2002 and Nutritional Risk Index) were associated with clinical outcomes including hospitalizations, need for surgery, disease flares, and length of stay (LOS). Sarcopenia was the most commonly evaluated NAT associated with outcomes including the need for surgery and post-operative complications. The SGA was not associated with clinical outcomes aside from LOS. CONCLUSION There is limited evidence correlating NSTs, NATs and clinical outcomes in IBD. Although studies support the association of NSTs/NATs with relevant outcomes, the heterogeneity calls for further studies before an optimal tool can be recommended. The NRS-2002, measures of sarcopenia and developments of novel NSTs/NATs, such as the MIRT, represent key, clinically-relevant areas for future exploration. | Suqing Li Michael Ney Tannaz Eslamparast Ben Vandermeer Kathleen P Ismond Karen Kroeker Brendan Halloran Maitreyi Raman Puneeta Tandon | 2019 | World Journal of Gastroenterology2019，25，28： | 9 |
| 5 | Intraoperative blood loss in orthotopic liver transplantation:The predictive factors显示文摘Liver transplantation has been associated with massive blood loss and considerable transfusion requirements. Bleeding in orthotopic liver transplantation is multifactorial. Technical difficulties inherent to this complex surgical procedure and pre operative derangements of the primary and secondary coagulation system are thought to be the principal causes of perioperative hemorrhage. Intraoperative practices such as massive fluid resuscitation and resulting hypothermia and hypocalcemia secondary to citrate toxicity further aggravate the preexisting coagulopathy and worsen the perioperative bleeding. Excessive blood loss and transfusion during orthotopic liver transplant are correlated with diminished graft survival and increased septic episodes and prolonged ICU stay. With improvements in surgical skills, anesthetic technique, graft preservation, use of intraoperative cell savers and overall perioperative management, orthotopic liver transplant is now associated with decreased intra operative blood losses. The purpose of this review is to discuss the risk factors predictive of increased intra operative bleeding in patients undergoing orthotopic liver transplant. | Chandra Kant Pandey Anshuman Singh Kamal Kajal Mandeep Dhankhar Manish Tandon Vijay Kant Pandey Sunaina Tejpal Karna | 2015 | World Journal of Gastrointestinal Surgery2015，7，6： | 8 |
| 6 | 居民健康调查资料中的缺失数据的多重估算显示文摘目的 解决居民健康调查数据中存在的数据缺失问题 ,充分利用所采集到的数据 ,得出更有效的统计推断。方法 运用建立在马尔科夫链蒙特卡罗方法基础上的多重估算技术 ,对缺失数据进行替换 ,产生多个完整的数据集 ,进行联合统计推断。结果 弥补了由于缺失数据所造成的信息损失 ,改善了统计推断的质量。结论 多重估算技术是解决社会调查资料中数据缺失问题的有效工具。 | 曹阳 Sadana Ritu Tandon Ajay | 2002 | 中国卫生统计2002，19，5： | 6 |
| 7 | 慢性胰腺炎──病因、发病机制及治疗的认识现状显示文摘 | Rakesh K Tandon Pramod K Garg 蒋晓玲 | 2002 | 胃肠病学2002，7，1： | 6 |
| 8 | High Prevalence of Antibiotic-Resistant Bacterial Infections Among Patients With Cirrhosis at a US Liver Center显示文摘 | Puneeta Tandon Angela DeLisle Jeffrey E. Topal Guadalupe Garcia–Tsao | 2012 | Clinical Gastroenterology and Hepatology2012，，11： | 5 |
| 9 | 营养不良:实验室指标vs营养评估显示文摘营养不良是患者并发症发生率和病死率的一项独立危险因素,并造成医疗费用的增高。然而,由于对营养不良没有一个统一的定义,也没有一个标准的营养不良筛查/诊断方法,导致全世界各地的医生对营养不良在认识上十分混乱,各地的临床实践也有着各不相同的标准。作为营养不良的危险因素,炎症的作用近期已被证实。组织学上,一些血清蛋白如白蛋白和前白蛋白被广泛用于监测患者的营养状态。然而,目前的研究热点是采用恰当的营养状态体格检查(NFPE)来诊断营养不良。目前认为,实验室指标本身不太可靠,只能作为NFPE的一个补充。今后的研究中需要筛选出一些诊断营养不良的血清生物学标志物,这些标志物必须是不受炎症状态影响且具有无创及价格相对低廉的优势。然而,一个完全的NFPE在营养不良的诊断中具有无可替代的作用。 | Shishira Bharadwaj Shaiva Ginoya Parul Tandon Tushar D.Gohel John Guirguis Hiren Vallabh Andrea Jevenn Ibrahim Hanouneh | 2016 | Gastroenterology Report2016，4，4： | 5 |
| 10 | 在有经历非肝的外科的肝疾病的病人的 Perioperative 风险因素显示文摘 The patients with liver disease present for various surgical interventions. Surgery may lead to complications in a significant proportion of these patients. These complications may result in considerable morbidity and mortality. Preoperative assessment can predict survival to some extent in patients with liver disease undergoing surgical procedures. A review of literature suggests nature and the type of surgery in these patients determines the peri-operative morbidity and mortality. Optimization of premorbid factors may help to reduce perioperative mortality and morbidity. The purpose of this review is to discuss the effect of liver disease on perioperative outcome; to understand various risk scoring systems and their prognostic significance; to delineate different preoperative variables implicated in postoperative complications and morbidity; to establish the effect of nature and type of surgery on postoperative outcome in patients with liver disease and to discuss optimal anaesthesia strategy in patients with liver disease. | Chandra Kant Pandey Sunaina Tejpal Karna Vijay Kant Pandey Manish Tandon Amit Singhal Vivek Mangla | 2012 | World Journal of Gastrointestinal Surgery2012，4，12： | 4 |
| 11 | Body mass index and colon cancer screening:The road ahead显示文摘Screening for colorectal cancer(CRC) has been associated with a decreased incidence and mortality from CRC.However,patient adherence to screening is less than desirable and resources are limited even indeveloped countries.Better identification of individuals at a higher risk could result in improved screening efforts.Over the past few years,formulas have been developed to predict the likelihood of developing advanced colonic neoplasia in susceptible individuals but have yet to be utilized in mass screening practices.These models use a number of clinical factors that have been associated with colonic neoplasia including the body mass index(BMI).Advances in our understanding of the mechanisms by which obesity contributes to colonic neoplasia as well as clinical studies on this subject have proven the association between BMI and colonic neoplasia.However,there are still controversies on this subject as some studies have arrived at different conclusions on the influence of BMI by gender.Future studies should aim at resolving these discrepancies in order to improve the efficiency of screening strategies. | Kanwarpreet Tandon Mohamad Imam Bahaa Eldeen Senousy Ismail Fernando Castro | 2015 | World Journal of Gastroenterology2015，21，5： | 4 |
| 12 | Crohn's disease presenting as acute gastrointestinal hemorrhage显示文摘Severe gastrointestinal(GI) hemorrhage is a rare complication of Crohn's disease(CD). Although several surgical and non-surgical approaches have been described over the last 2 decades this complication still poses significant diagnostic and therapeutic challenges. Given the relative infrequency of severe bleeding in CD, available medical literature on this topic is mostly in the form of retrospective case series and reports. In this article we review the risk factors, diagnostic modalities and treatment options for the management of CD presenting as GI hemorrhage. | Amareshwar Podugu Kanwarpreet Tandon Fernando J Castro | 2016 | World Journal of Gastroenterology2016，22，16： | 4 |
| 13 | Who benefits from percutaneous closure of patent foramen ovale vs medical therapy for stroke prevention? In-depth and updated metaanalysis of randomized trials显示文摘BACKGROUND A few randomized clinical trials(RCT) and their meta-analyses have found patent foramen ovale closure(PFOC) to be beneficial in prevention of stroke compared to medical therapy. Whether the benefit is extended across all groups of patients remains unclear.AIM To evaluate the efficacy and safety of PFOC vs medical therapy in different groups of patients presenting with stroke, we performed this meta-analysis of RCTs.METHODS Electronic search of PubMed, EMBASE, Cochrane Central, CINAHL and ProQuest Central and manual search were performed from inception through September 2018 for RCTs. Ischemic stroke(IS), transient ischemic attack(TIA), a composite of IS, TIA and systemic embolism(SE), mortality, major bleeding,atrial fibrillation(AF) and procedural complications were the major outcomes.Random-effects model was used to perform analyses.RESULTS Meta-analysis of 6 RCTs including 3560 patients showed that the PFOC,compared to medical therapy reduced the risk of IS [odds ratio: 0.34; 95%confidence interval: 0.15-0.78; P = 0.01] and the composite of IS, TIA and SE [0.55(0.32-0.93); P = 0.02] and increased the AF risk [4.79(2.35-9.77); P < 0.0001]. No statistical difference was observed in the risk of TIA [0.86(0.54-1.38); P = 0.54],mortality [0.74(0.28-1.93); P = 0.53] and major bleeding [0.81(0.42-1.56); P = 0.53]between two strategies. Subgroup analyses showed that compared to medical therapy, PFOC reduced the risk of stroke in persons who were males, ≤ 45 years of age and had large shunt or atrial septal aneurysm.CONCLUSION In certain groups of patients presenting with stroke, PFOC is beneficial in preventing future stroke compared to medical therapy. | Khagendra Dahal Adil Yousuf Hussam Watti Brannen Liang Sharan Sharma Jharendra Rijal Pavan Katikaneni Kalgi Modi Neeraj TANDon Michael Azrin Juyong Lee | 2019 | World Journal of Cardiology2019，11，4： | 4 |
| 14 | 肝硬化患者静脉曲张性出血与非静脉曲张性出血临床结局的比较显示文摘【据《J Gastroenterol Hepatol》2018年3月报道】题:肝硬化患者静脉曲张性出血与非静脉曲张性出血临床结局的比较(作者Tandon P等)
急性上消化道出血(UGIB)在肝硬化患者中有着显著的发病率和死亡率。其可分为急性静脉曲张性出血(AVB)或非静脉曲张性出血(NVB)。死亡率、住院时间(LOS)和30d再入院的差异尚待确定。苓研究旨在评估因UGIB住院的肝硬化患者在上述临床结局方面的差异。 | Tandon P 谢智钦 刘智勇 邓飞杰 | 2018 | 临床肝胆病杂志2018，34，5： | 3 |
| 15 | Endoscopic botox injections in therapy of refractory gastroparesis显示文摘Gastroparesis(GP) is a common disease seen in gastroenterology practice particularly in western countries, and it may be underdiagnosed. The available drug therapies for this condition are quite disappointing. Botulinum toxin type A(BT) has been found to be effective therapy in various spastic disorders of smooth muscle of gastrointestinal tract. However, the benefits of BT injections in GP have been unclear. Several retrospective and open label studies have shown clinical advantages of intrapyloric Botulinum toxin type A injections, while two small randomized trials did not show positive results. Therefore, the available published studies yielded conflicting results leading to fading out of botox therapy for GP. We recognize possible clinical benefit of BT injections without any disadvantages of this treatment. We are calling for revisiting the endoscopy guided botox therapy in refractory GP. In this review we discuss important features of these studies pointing out differences in results among them. Differences in patient selection, doses and method of administration of botox toxin in the prior studies may be the cause of conflicting results. The mechanism of action, indications, efficacy and side-effects of BT are reviewed. Finally, we recognize limited evidence to recommend BT in GP and calling attention for future research in this field since no advances in drug management had been made in the last two decades. | Andrew Ukleja Kanwarpreet Tandon Kinchit Shah Alicia Alvarez | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，8： | 3 |
| 16 | World Gastroenterology Organisation Global Guideline: Constipation—A Global Perspective显示文摘 | Greger Lindberg Saeed S. Hamid Peter Malfertheiner Ole Ostergaard Thomsen Luis Bustos Fernandez James Garisch Alan Thomson Khean-Lee Goh Rakesh Tandon Suliman Fedail Benjamin C.Y. Wong Aamir Ghafoor Khan Justus H. Krabshuis Anton LeMair | 2011 | Journal of Clinical Gastroenterology2011，，6： | 3 |
| 17 | Antidiabetic activity of 50% ethanolic extract of Ricinus communis and its purified fractions显示文摘 | Poonam Shokeen Prachi Anand Y. Krishna Murali Vibha Tandon | 2008 | Food and Chemical Toxicology2008，，11： | 3 |
| 18 | 印度Leh地区沙棘果实脂肪酸的初步研究显示文摘本文用气相色谱分析法对Leh地区沙棘果油中脂肪酸成分(含量)进行了分析测定。结果表明:沙棘果油中脂肪(酸)含量为24.9%,其中主要成分为棕榈油酸(42.06%)、棕榈酸(28.11%)和油酸 (12.29%)。 | Shishir Tandon R.C.Sawhney 赵梅霞 | 2005 | 国际沙棘研究与开发2005，3，4： | 2 |
| 19 | Role of interstitial cells of Cajal in motility disorders of the bowel显示文摘 | Jain D Moussa K Tandon M | 2003 | Am J Gastroenterol2003，98，3： | 2 |
| 20 | Managing the post–liver transplantation anastomotic biliary stricture: multiple plastic versus metal stents: a systematic review显示文摘 | Dina Kao Sergio Zepeda-Gomez Puneeta Tandon Vince G. Bain | 2013 | Gastrointestinal Endoscopy2013，，5： | 2 |
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