7篇
您的检索式：作者名="Viswanatha L"
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| 1 | Methanolic extract of Momordica cymbalaria enhances glucose uptake in L6 myotubes in vitro by up-regulating PPAR-γ and GLUT-4显示文摘The present study was undertaken to evaluate the influence of the methanolic fruit extract of Momordica cymbalaria(MFMC) on PPARγ(Peroxisome Proliferator Activated Receptor gamma) and GLUT-4(Glucose transporter-4) with respect to glucose transport. Various concentrations of MFMC ranging from 62.5 to 500 μg·mL-1 were evaluated for glucose uptake activity in vitro using L6 myotubes, rosiglitazone was used as a reference standard. The MFMC showed significant and dose-dependent increase in glucose uptake at the tested concentrations, further, the glucose uptake activity of MFMC(500 μg·mL-1) was comparable with rosigilitazone. Furthermore, MFMC has shown up-regulation of GLUT-4 and PPARγ gene expressions in L6 myotubes. In addition, the MFMC when incubated along with cycloheximide(CHX), which is a protein synthesis inhibitor, has shown complete blockade of glucose uptake. This indicates that new protein synthesis is required for increased GLUT-4 translocation. In conclusion, these findings suggest that MFMC is enhancing the glucose uptake significantly and dose dependently through the enhanced expression of PPARγ and GLUT-4 in vitro. | Puttanarasaiah Mahesh Kumar Marikunte V Venkataranganna Kirangadur Manjunath Gollapalle L Viswanatha Godavarthi Ashok | 2014 | Chinese Journal of Natural Medicines2014，12，12： | 2 |
| 2 | Ameliorative effect of Koflet formulations against pyridine-induced pharyngitis in rats 显示文摘 | Viswanatha C L Rafiq M Thippeswamy A H M Yuvaraj H C Kavya K J Mirza R B Suryakant A Mohammed A Patki P S Pushpalatha H B Prafulla S C Shyam R | 2014 | Toxicology Reports2014，1，： | 1 |
| 3 | Darier- Roussy sarcoidosis mimicking metastatic breast cancer 显示文摘 | Viswanatha L Palladea S Krishnamurthyb B | 2009 | Case Rep Oncol2009，2，3： | 1 |
| 4 | 1,2,3,4,6 Pen- ta-O-galloyl-beta-d-glucose, a bioactivity guided isolated compound from Mangiferaindica inhibits l lbeta-HSD-1 and ameliorates high fat diet-induced diabetes in C57BL/6 mice 显示文摘 | Mohan C G Viswanatha G L Savinay G | 2013 | Phytomedicine2013，20，5： | 1 |
| 5 | Darier Roussy sarcoidosis mimicking metastatic breast cancer 显示文摘 | Viswanatha L Pa|ladea S Krishnamurthyb B | 2009 | Case Rep Oncol2009，2，3： | 1 |
| 6 | Temperature dependence of 'elementary processes' in doping semiconductor nanocrystals 显示文摘 | CHEN D A VISWANATHA R ONG G L | 2009 | J Am Chem Soc2009，131，： | 1 |
| 7 | Protective effect of leaves of Raphinus sativus Linn on experimentally induced gastric ulcers in rats显示文摘 | DEVARAJ V C KRISHNA B G VISWANATHA G L | 2011 | Saudi Pharmaceutical Journal2011，19，3： | 1 |
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