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15篇 您的检索式：作者名="Vogel CF"

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		题名	作者	年代	出处	被引量
	1	ATG16L1 and NOD2 polymorphisms enhance phagocytosis in monocytes of Crohn's disease patients显示文摘AIM:To investigate if the presence of relevant genetic polymorphisms has effect on the effectual clearance of bacteria by monocytes and granulocytes in patients with Crohn’s disease(CD).METHODS:In this study,we assessed the differential responses in phagocytosis by measuring the phagocytic activity and the percentage of active phagocytic monocytes and granulocytes in inflammatory bowel disease patients as well as healthy controls.As both autophagy related like 1(ATG16L1)and immunityrelated guanosine triphosphatase gene are autophagy genes associated with CD and more recently nucleo-tide-binding ligomerization domain-containing protein2(NOD2)has been identified as a potent inducer of autophagy we genotyped the patients for these variants and correlated this to the phagocytic reaction.The genotyping was done with restriction fragment length polymorphisms analysis and the phagocytosis was determined with the pHrodo?Escherichia coli Bioparticles Phagocytosis kit for flowcytometry.RESULTS:In this study,we demonstrate that analysis of the monocyte and granulocyte populations of patients with CD and ulcerative colitis showed a comparable phagocytic activity(ratio of mean fluorescence intensity)between the patient groups and the healthy controls.CD patients show a significantly higher phagocytic capacity(ratio mean percentage of phagocytic cells)compared to healthy controls(51.91%±2.85%vs 37.67%±7.06%,P=0.05).The extend of disease was not of influence.However,variants of ATG16L1(WT:2.03±0.19 vs homozygoot variant:4.38±0.37,P<0.009)as well as NOD2(C-ins)(heterozygous variant:42.08±2.94 vs homozygous variant:75.58±4.34(P=0.05)are associated with the phagocytic activity in patients with CD.CONCLUSION:Monocytes of CD patients show enhanced phagocytosis associated with the presence of ATG16L1 and NOD2 variants.This could be part of the pathophysiological mechanism resulting in the disease.	Simone CS Wolfkamp Caroline Verseyden Esther WM Vogels Sander Meisner Kirsten Boonstra Charlotte P Peters Pieter CF Stokkers Anje A te Velde	2014	World Journal of Gastroenterology2014，20，10：	2
	2	The ratio of Matriptase/ HAI-1 mRNA is higher in colorectal cancer adenomas and carcinomas than corresponding tissue from control individuals 显示文摘	Vogel LK Saebo M Skjelbred CF	2006	BMC Cancer2006，6，：	1
	3	A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family显示文摘	Vogel CF Matsumura F	2009	Biochem Pharmaeol2009，77，4：	1
	4	Characterization of the pattern of the nongenomic signaling pathway through which TCDD-induces early inflammatory responses in U937 human macrophages显示文摘	Sciullo EM Dong B Vogel CF	2009	Chemosphere2009，74，11：	1
	5	Association of serum levels of polychlorinated biphenyls with IL-8 mRNA expression in blood samples from asthmatic and non-asthmatic Japanese children显示文摘	Tsuji M Vogel CF Koriyama C	2012	Chemosphere2012，87，11：	1
	6	Regional response of myocardial acceleration during isovolumic contraction during dobutamine stress echocardiography:a color tissue Doppler study and comparison with angiocardiographic findings显示文摘	Pauliks LB Vogel M M(a)dler CF		0，，10：	1
	7	Critical role of cyclooxy-genase - 2 activation in pathogenesis of hydronephrosis caused by lacta-tional exposure of mice to dioxin显示文摘	Nishimura N Matsumura F Vogel CF	2008	Toxicol Appl Pharmacol2008，231，3：	1
	8	Cross-talk be- tween aryl hydrocarbon receptor and the inflammatory response: a role for nuclear factor-kappaB 显示文摘	Vogel CF Khan EM Leung PS	2014	J Biol Chem2014，289，3：	1
	9	Aryl hydrocarbonreceptor signaling mediates expression of indoleamine 2,3-dioxygenase 显示文摘	Vogel CF Goth SR Dong B	2009	Biochem Biophys Res Commun2009，375，3：	1
	10	Regional response of myocardial acceleration during isovolumic contraction during dobutamine stress echocardiography:a color tissue Doppler study and comparison with angiocardiographic findings显示文摘	Pauliks LB Vogel M Mdler CF	2005	Echocardiography2005，22，10：	1
	11	Unique biochemical and molecu- lar biological mechanism of synergistic actions of formamidine com- pounds on selected pyrethroid and neonicotinoid insecticides on the fourth instar larvae of Aedes aegypti (Diptera: Culicidae) 显示文摘	Ahmed MA Vogel CF Matsumura F	2015	Pestic Biochem Physiol2015，120，15：	1
	12	Dioxin increases C/EBPbeta transcription by activating cAMP/protein kinase A显示文摘	Vogel CF Seiullo E Park S	2004	J Biol Chem2004，279，10：	1
	13	Regional response of myocardial acceleration during isovolumie contraction during dobutamine stress echocardiography:a color tissue Doppler study and comparison with angiocardiographic findings 显示文摘	Pauliks LB Vogel M Madler CF	2005	Echocardiography2005，22，10：	1
	14	Critical role of cydooxygenase-2 activation in pathogenesis of hydrone-phrosis caused by lactational exposure of mice to dioxin显示文摘	Nishimura N Matsumum F Vogel CF		0，，03：	1
	15	Cross-talk between aryl hydro- carbon receptor and the inflammatory response: a role for nuclear fac- tor-KB 显示文摘	Vogel CF Khan EM Leung PS	2014	J Biol Chem2014，289，3：	1

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