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6篇 您的检索式:作者名="W.White"
    题名 作者 年代 出处 被引量
1土层的概率模型及其在桩基分析中的应用显示文摘本文讨论土层概率模拟的一些概念,特别介绍随机场的理论及一些新发展。该理论考虑土性的变异及由抽样所做成的误差。本文亦提出一种分析粘性土中桩基承载力的概率分析方法,并透过算例作具体说明。李启信 W.White 楚剑 赵敏敏 1989岩土工程学报1989,11,6:11
2Analysis of TRPA1 antagonist,A-967079,in plasma using high-performance liquid chromatography tandem mass-spectrometry显示文摘The noxious effects from exposure to toxic inhalation hazards(TIHs,such as isocyanates,chlorine,etc.)are known to be triggered by the activation of transient receptor potential ankyrin 1(TRPA1)ion channel.Antagonists of TRPA1 have shown near complete attenuation of the noxious effects from TIH exposure.One of the TRPA1 antagonists,(1E,3E)-1-(4-fluorophenyl)-2-methyl-1-pentene-3-one oxime(A-967079),has shown impressive efficacy,high selectivity,high potency,and oral bioavailability.Although a vali-dated method to quantify A-967079 in biological matrices is vital for the further development of A-967079 as a therapeutic agent,no method for its analysis from any matrix is currently available.Hence,a rapid and simple HPLC-MS/MS method was developed and validated to quantify A-967079 in rabbit plasma.The method presented here features an excellent LOD of 25 nM and a wide linear range(0.05-200μM),with good accuracy and precision(100±10.5%and<14.2%relative standard deviation,respectively).The stability of A-967079 in plasma was excellent for most of the storage conditions evaluated.The method was successfully applied to determine A-967079 from treated animals and it may facilitate the development of this TRPA1 antagonist as a therapeutic agent against the noxious effects of TIH exposure.Obed A.Gyamfi Nesta Bortey-Sam Abigail B.Donkor Carl W.White Brian A.Logue 2020Journal of Pharmaceutical Analysis2020,10,2:2
3Septic arthritis due to Aeromonas hydrophila: case report and review of the literature显示文摘J. P.Elwitigala D. S.Higgs S.Namnyak J. W.White A.Yaneza 2005International Journal of Clinical Practice2005,,:1
4GJB2 Mutations in Mongolia: Complex Alleles, Low Frequency, and Reduced Fitness of the Deaf显示文摘MustafaTekin Xia‐JuanXia RadnaabazarErdenetungalag Filiz BasakCengiz Thomas W.White JanchivRadnaabazar BegzsurenDangaasuren HakkiTastan Walter E.Nance ArtiPandya 2010Annals of Human Genetics2010,,2:1
5Microstructural Control of a 70% Silicon Nitride– 30% Barium Aluminum Silicate Self‐Reinforced Composite显示文摘FengYu NandakumarNagarajan YiFang Kenneth W.White 2004Journal of the American Ceramic Society2004,,1:1
6Prediction of tensile power law creep constants from compression and bend data for ZrB_(2)-20 vol% SiC composites at 1800℃显示文摘Here we consider our four-point flexure and compression creep results obtained under Ar protection at 1800℃ to predict the tensile creep behavior of a ZrB_(2)-20 vol%SiC ultra-high temperature ceramic.Assuming power law creep,and based on four-point bend data,we estimated the uniaxial creep parameters using an analytical method present in the literature.Both predicted and experimental compressive stress exponents were found to be in excellent agreement,1.85 and 1.76 respectively,while observation of the microstructure suggested a combination of diffusion and grain boundary sliding creep mechanisms in compression.Along with the microstructural evidence associated with the tensile regions of the flexure specimens,the predicted tensile stress exponent of 2.61 exceeds the measured flexural value of 2.2.We assert an increasing role of cavitation to the creep strain in pure tension.This cavitation component adds to the dominant grain boundary sliding mechanism as described below and elsewhere for flexural creep.Ali KHADIMALLAH Marc W.BIRD Kenneth W.WHITE 2017Journal of Advanced Ceramics2017,6,4:0
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