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| 1 | Trends and outcomes of pancreaticoduodenectomy for periampullary tumors: A 25-year single-center study of 1000 consecutive cases显示文摘AIM To evaluate the evolution, trends in surgical approaches a n d r e c o n s t r u c t i o n t e c h n i q u e s, a n d i m p o r t a n t lessons learned from performing 1000 consecutive pancreaticoduodenectomies(PDs) for periampullary tumors.METHODS This is a retrospective review of the data of all patients who underwent PD for periampullary tumor during the period from January 1993 to April 2017. The data were categorized into three periods, including early period(1993-2002), middle period(2003-2012), and late period(2013-2017).RESULTS The frequency showed PD was increasingly performed after the year 2000. With time, elderly, cirrhotic and obese patients, as well as patients with uncinate process carcinoma and borderline tumor were increasingly selected for PD. The median operative time and postoperative hospital stay decreased significantly over the periods. Hospital mortality declined significantly, from 6.6% to 3.1%. Postoperative complications significantly decreased, from 40% to 27.9%. There was significant decrease in postoperative pancreatic fistula in the second 10 years, from 15% to 12.7%. There was a significant improvement in median survival and overall survival among the periods.CONCLUSION Surgical results of PD significantly improved, with mortality rate nearly reaching 3%. Pancreatic reconstruction following PD is still debatable. The survival rate was also improved but the rate of recurrence is still high, at 36.9%. | ayman el nakeeb waleed askar ehab atef ehab el hanafy ahmad m sultan tarek salah ahmed shehta mohamed el sorogy emad hamdy mohamed el hemly ahmed a el-geidi tharwat kandil mohamed el shobari talaat abd allah amgad fouad mostafa abu zeid ahmed abu el eneen nabil gad el-hak gamal el ebidy omar fathy ahmed sultan mohamed abdel wahab | 2017 | World Journal of Gastroenterology2017，23，38： | 15 |
| 2 | Predictors of long term survival after hepatic resection for hilar cholangiocarcinoma:A retrospective study of 5-year survivors显示文摘AIM:To determine predictors of long term survival after resection of hilar cholangiocarcinoma(HC) by comparing patients surviving > 5 years with those who survived < 5 years.METHODS:This is a retrospective study of patients with pathologically proven HC who underwent surgical resection at the Gastroenterology Surgical Center,Mansoura University,Egypt between January 2002 and April 2013.All data of the patients were collected from the medical records.patients were divided into two groups according to their survival:patients surviving less than 5 years and those who survived > 5 years.RESULTS:There were 34(14%) long term survivors(5 year survivors) among the 243 patients.Fiveyear survivors were younger at diagnosis than those surviving less than 5 years(mean age,50.47 ± 4.45 vs 54.59 ± 4.98,p = 0.001).Gender,clinical presentation,preoperative drainage,preoperative serum bilirubin,albumin and serum glutamic-pyruvic transaminase were similar between the two groups.The level of CA 19-9 was significantly higher in patients surviving < 5 years(395.71 ± 31.43 vs 254.06 ± 42.19,p = 0.0001).Univariate analysis demonstrated nine variables to be significantly associated with survival > 5 year,includingyoung age(p = 0.001),serum CA19-9(p = 0.0001),non-cirrhotic liver(p = 0.02),major hepatic resection(p = 0.001),caudate lobe resection(p = 0.006),well differentiated tumour(p = 0.03),lymph node status(0.008),R0 resection margin(p = 0.0001) and early postoperative liver cell failure(p = 0.02).CONCLUSION:Liver status,resection of caudate lobe,lymph node status,R0 resection and CA19-9 were demonstrated to be independent risk factors for long term survival. | Mohamed Abd El Wahab Ayman El Nakeeb Ehab El Hanafy Ahmad M Sultan Ahmed Elghawalby Waleed Askr Mahmoud Ali Mohamed Abd El Gawad Tarek Salah | 2016 | World Journal of Gastrointestinal Surgery2016，8，6： | 10 |
| 3 | Impact of cirrhosis on surgical outcome after pancreaticoduodenectomy显示文摘AIM:To elucidate surgical outcomes of pancreaticoduodenectomy(PD)in patients with liver cirrhosis.METHODS:We studied retrospectively all patients who underwent PD in our centre between January 2002and December 2011.Group A comprised patients with cirrhotic livers,and Group B comprised patients with non-cirrhotic livers.The cirrhotic patients had ChildPugh classes A and B(patient’s score less than 8).Preoperative demographic data,intra-operative data and postoperative details were collected.The primary outcome measure was hospital mortality rate.Secondary outcomes analysed included duration of the operation,postoperative hospital stay,postoperative morbidity and survival rate.RESULTS:Only 67/442 patients(15.2%)had cirrhotic livers.Intraoperative blood loss and blood transfusion were significantly higher in group A(P=0.0001).The mean surgical time in group A was significantly longer than that in group B(P=0.0001).Wound complications(P=0.02),internal haemorrhage(P=0.05),pancreatic fistula(P=0.02)and hospital mortality(P=0.0001)were significantly higher in the cirrhotic patients.Postoperative stay was significantly longer in group A(P=0.03).The median survival was 19 mo in group A and 24 mo in group B.Portal hypertension(PHT)was present in 16/67 cases of cirrhosis(23.9%).The intraoperative blood loss and blood transfusion were significantly higher in patients with PHT(P=0.001).Postoperative morbidity(0.07)and hospital mortality(P=0.007)were higher in cirrhotic patients with PHT.CONCLUSION:Patients with periampullary tumours and well-compensated chronic liver disease should be routinely considered for PD at high volume centres with available expertise to manage liver cirrhosis.PD is associated with an increased risk of postoperative morbidity in patients with liver cirrhosis;therefore,it is only recommended in patients with Child A cirrhosis without portal hypertension. | Ayman El Nakeeb Ahmad M Sultan Tarek Salah Mohamed El Hemaly Emad Hamdy Ali Salem Ahmed Moneer Rami Said Ahmed AbuEleneen Mostafa Abu Zeid Talaat Abdallah Mohamed Abdel Wahab | 2013 | World Journal of Gastroenterology2013，19，41： | 3 |
| 4 | Damage detection in bridges using model curvatures:Application to a real damage scenario显示文摘 | Abedel Wahab M M | 1991 | Journal of Sound and Vibra-tion1991，226，2： | 1 |
| 5 | Synthesis and Character-ization of Multifunctional Periodic Mesoporous Organosilica fromDiureidophenylene Bridged Organosilica Precursor 显示文摘 | WAHAB M A CHU S W^ANAND C | 2012 | J NanosciNanotechno2012，12，6： | 1 |
| 6 | The effects of partially sub-string Indian carp or adding silver carp on poly-cultures inclu-ding small indigenous fish species ( SIS) 显示文摘 | Milstein A Kadir A Wahab M | 2008 | Aquaculture2008，279，14： | 1 |
| 7 | TGF-beta1-induced connective tissue growth factor (CCN2) expression in human renal proximal tubule epithelial cells requires Ras/MEK/ERK and Smad signalling显示文摘 | PHANISH M K WAHAB N A HENDRY B M | 2005 | Nephron Exp Nephrol2005，100，4： | 1 |
| 8 | Protein expression and molecular analysis of c-myc gene in primary breast carcinomas using immunohistochemistry and differential polymerase chain reaction显示文摘 | Naidu R Wahab NA Yadav M | 2002 | Int J Mol Med2002，9，2： | 1 |
| 9 | An Electrochemical and Esca Study on the Tarnishing of Silver in Solutions of Different pS and pH Values显示文摘 | DIN A M Shams El KADER J M Abd El WAHAB F M Abd El | 1985 | Electrochimica Acta1985，30，4： | 1 |
| 10 | The Prediction of Burn - through during In - service Welding of Gas Pipelines 显示文摘 | Sabapathy P N Wahab M A Painter M J | 2000 | International Journal of Pressure Vessels and Piping2000，77，11： | 1 |
| 11 | Ammonium biosorption onto sawdust: FTIR analysis, kinetics and adsorption isotherms modeling 显示文摘 | WAHAB M A Jellali S Jedidi N | 2010 | Bioresource Technology2010，101，14： | 1 |
| 12 | Effect of corrosion prevention compounds on fatigue life in 2024-T3 aluminum alloy显示文摘 | Wahab M A Park J H Alama M S | 2006 | Journal of Materials Pro- cessing Technology2006，174，1： | 1 |
| 13 | expressionof connective tissue growth factor in human renal fibrosis : reguia-tory role of RhoA and cAM P显示文摘 | Heusinger-Ribeiro J Eberlein M Wahab N A | 2001 | J Am Soc Nephrol2001，12，9： | 1 |
| 14 | Novel Model- ing for the Prediction of Aged Transformer Oil Characteris- tics显示文摘 | Wahab M A A Hamada M M Zeitoun A G | 1999 | Electric Power Systerms Research1999，51，1： | 1 |
| 15 | Formulation and physical,in vitro and ex vivo evaluation of transdermal ibuprofen hydrogels containing turpentine oil as penetration enhancer显示文摘 | Khan N R Khan G M Wahab A | 2011 | Pharmazie2011，66，11： | 1 |
| 16 | Effect of gallium ions on the electrochemical behaviour of Al, Al - Sn Al - Zn and Al - Zn - Sn alloys in chloride solutions 显示文摘 | ELSHAYEB H A ADBEI WAHAB F M | 2001 | Corrosion Science2001，43，： | 1 |
| 17 | The prediction of burn-through during in-service welding of gas pipelines显示文摘 | Sabapathy P N Wahab M A Painter M J | 2000 | International Journal of Pressure Vessels and Piping2000，77，11： | 1 |
| 18 | Price dynamics and error correction in stock index and stock index futures markets:a cointegration approach显示文摘 | Wahab M Lashgari M | 1993 | The Journal of Futures Markets1993，13，： | 1 |
| 19 | Characterization of ammonium retention processes onto Cactus leaves fibers using FTIR, EDX and SEM analysis显示文摘 | Wahab M A Boubakri H Jellali S | 2012 | Journal of Hazardous Materials2012，241，10： | 1 |
| 20 | Creep damage simulation of thick-walled tubes using the θ projection concept显示文摘 | Loghman A Wahab M A | | 0，，67： | 1 |
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