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| 1 | Colon cancer and the immune system:The role of tumor invading T cells显示文摘Colon cancer is still one of the leading causes of cancer death worldwide. Although the host immune system has been shown to react against tumor cells, mainly through tumor infi ltrating lymphocytes and NK cells, tumor cells may utilize different ways to escape anti-tumor immune response. Tumor infi ltration of CD8+ and CD4+ (T-bet+) effector T cells has been attributed to a beneficial outcome, and the enhancement of T cell activation through T cell receptor stimulation and co-stimulatory signals provides promising strategies for immunotherapy of colon cancer. Growing evidence supports a role for the Fas/FasL system in tumor immunology, although the mechanisms and consequences of FasL activation in colon cancer are not completely understood. In animal models, depletion of regulatory T cells (CD4+ CD25+ T cells) can enhance the anti-tumor immune response under certain conditions. Taken together, recent insights in the immune reaction against colon carcinoma have provided new approaches to immunotherapy, although much remains to be learned about the exact mechanisms. | Maximilian Waldner Carl C Schimanski Markus F Neurath | 2006 | World Journal of Gastroenterology2006，12，45： | 15 |
| 2 | Smad7 expression in T ceils prevents colitis associated cancer 显示文摘 | Rizzo A Waldner M J Stolfi C | 2011 | Cancer Res2011，71，24： | 1 |
| 3 | Associations between health and productivity in cow-calf beef herds and persistent infection with bovine viral diarrhea virus,antibodies against bovine viral diarrhea virus,or antibodies against infectious bovine rhinotracheitis virus in calves显示文摘 | Waldner C L Kennedy R I | 2008 | Am J Vet Res2008，69，7： | 1 |
| 4 | Smad7 expression in T cells pre- vents colitis - associated cancer 显示文摘 | Rizzo A Waldner M J Stolfi C | 2011 | Cancer Res2011，71，24： | 1 |
| 5 | A comparison of diagnostic techniques for postpartum endometritis in dairy cattle 显示文摘 | Barlund C S Carruthers T D Waldner C L | 2008 | Theriogenology2008，69，6： | 1 |
| 6 | Managing lead exposure and toxicity in cow-calf herds to minimize the potential for food residues显示文摘 | Waldner C Checkley S Blakley B | 2002 | Journal of Veterinary Diagnostic Investigation2002，14，6： | 1 |
| 7 | Hot topic:an association between a leptin single nueleotide polymorphism and milk and protein yield显示文摘 | BUCHANAN F C Van KESSEL A G WALDNER C | 2003 | J Dairy Sci2003，86，10： | 1 |
| 8 | A comparison of diagnostic techniques for postpartum endometritis in dairy cattle显示文摘 | BARLUND C S CARRUTHERS T D WALDNER C L | 2008 | Theriog- enology2008，69，6： | 1 |
| 9 | Distribution of Salmonella serovars in breeding,nursery,and grow-to-finish pig,and risk factors for shedding in ten farrow-to-finish swine farms in Al-berta and Saskatchewan显示文摘 | Wilkins W Rajic A Waldner C | | 0，，02： | 1 |
| 10 | Antimicro- bial resistance of fecal Escherichia coli isolated from grow-finish pigs in 20 herds in Alberta and Saskatchewan 显示文摘 | Rosengren L Waldner C Reid-Smith R | 2008 | Can J Vet Res2008，72，2： | 1 |
| 11 | Adaptive locomotor training on an end-effector gait robot显示文摘 | Tomelleri C Waldner A Wemer C | 2011 | IEEE Int Conf Rehabil Robot2011，，： | 1 |
| 12 | Propionibacteria fed to dairy cows: effects on energy bal- ance, plasma metabolites and hormones, and reproduction 显示文摘 | FRANCISCO C C CHAMBERLAIN C S WALDNER D N | 2002 | Journal of Dairy Science2002，85，： | 1 |
| 13 | Hot Topic: An Association between a leptin Single Nucleotide Polymorphism and Milk and Protein Yield显示文摘 | Buchanan F C Van kessel A G Waldner C | 2003 | Journal of Dairy Science2003，86，1： | 1 |
| 14 | A comparison of diagnostic techniques for postpartum endometritis in dairy cattle显示文摘 | Barlund C S Carruthers T D Waldner C L | | 0，，： | 1 |
| 15 | A new gait machine G-EO for stair climbing and descending in non-ambulatory neurological patients显示文摘 | Werner C Waldner A Tomelleri C | | 0，，01： | 1 |
| 16 | Cataracts in 44 dogs (77eyes):A comparison of outcomes for no treatment, topical medical management, orphacoemulsification with intraocular lens implantation 显示文摘 | Christine C Lim Shannan C Bakker Cheryl L Waldner | 2011 | The Canadian Veterinary Journal2011，52，3： | 1 |
| 17 | Smad7 expres- sion in T cells prevents colitis-associated cancer 显示文摘 | RIZZO A WALDNER MJ STOLFI C | 2011 | Cancer Res2011，71，24： | 1 |
| 18 | Priority setting in health authorities: a novel approach to a historical activity 显示文摘 | Mitton C Patten S Waldner H | 2003 | Social Science & Medicine2003，57，9： | 1 |
| 19 | Thl specific cell surface protein TIM 3 regulates macrophage activation and severity of an autoimmune disease 显示文摘 | Monney L Sabatos C A Gaglia J L Ryu A Waldner H Chernova T | 2002 | Nature2002，415，： | 1 |
| 20 | The photo- fenton reaction and the TiO2/UV process for waste water treatment - novel developments显示文摘 | Bauer R Waldner C Fallmann H | 1999 | Catalysis Today1999，53，1： | 1 |
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