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| 1 | Effect of propranolol on the splanchnic and peripheral renin angiotensin system in cirrhotic patients显示文摘AIM:To evaluate the effect of β-blockade on angiotensins in the splanchnic and peripheral circulation of cirrhotic patients and also to compare hemodynamic parameters during liver transplantation according to propranolol pre-treatment or not. METHODS:Patients were allocated into two groups:outpatients with advanced liver disease(LD) and during liver transplantation(LT). Both groups were subdivided according to treatment with propranolol or not. Plasma was collected through peripheral venipuncture to determine plasma renin activity(PRA),Angiotensin(Ang) Ⅰ,Ang Ⅱ,and Ang-(1-7) levels by radioimmunoassay in LD group. During liver transplantation,hemodynamic parameters were determined and blood samples were obtained from the portal vein to measure renin angiotensin system(RAS) components.RESULTS:PRA,Ang Ⅰ,Ang Ⅱ and Ang-(1-7) were signifi cantly lower in the portal vein and periphery in all subgroups treated with propranolol as compared to non-treated. The relationships between Ang-(1-7) and Ang Ⅰ levels and between Ang Ⅱ and Ang Ⅰ were significantly increased in LD group receiving propranolol. The ratio between Ang-(1-7) and Ang Ⅱ remained unchanged in splanchnic and peripheral circulation in patients under β-blockade,whereas the relationship between Ang Ⅱ and Ang Ⅰ was significantly increased in splanchnic circulation of LT patients treated with propranolol. During liver transplantation,cardiac output and index as well systemic vascular resistance and index were reduced in propranolol-treated subgroup. CONCLUSION:In LD group,propranolol treatment reduced RAS mediators,but did not change the ratio between Ang-(1-7) and Ang Ⅱ in splanchnic and peripheral circulation. Furthermore,the modification of hemodynamic parameters in propranolol treated patients was not associated with changes in the angiotensin ratio. | Walkíria Wingester Vilas-Boas Antnio Ribeiro-Oliveira Jr Renata da Cunha Ribeiro Renata Lúcia Pereira Vieira Jerusa Almeida Ana Paula Nadu Ana Cristina Sim■es e Silva Robson Augusto Souza Santos | 2008 | World Journal of Gastroenterology2008，14，44： | 2 |
| 2 | Range-Doppler Imaging of Rotating Objects 显示文摘 | Walk J L | 1980 | IEEE Transon AES1980，16，1： | 1 |
| 3 | IEEE 802 Wireless Systems - Protocols, Multi - Hop Mesh/Rdaying 显示文摘 | Walke B Marigold A Berlemann L | 2006 | Performance and Spectrum Coexistence2006，19，： | 1 |
| 4 | The association of symptoms with health outcomes in chronically ill adults显示文摘 | WALKE L M BYERS A L GALLO W T | 2007 | J Pain Symptom Manage2007，33，1： | 1 |
| 5 | Range-Doppler imaging of rotating objects显示文摘 | | 1980 | IEEE Trans on AES1980，16，1： | 1 |
| 6 | Possible involvement of abscisic acid of daylily petals显示文摘 | PANAVAS T WALK E L RUBINSTEIN B | 1998 | Journal of Botany1998，49，： | 1 |
| 7 | Ghettos in Canada' s cities? Racial segregation, ethnic enclaves and poverty concentration in Canadian urban areasp显示文摘 | Walks R A Bourne L S | 2006 | The Canadian Geographer 2006 (3)2006，，： | 1 |
| 8 | A 30-Min physical education program improves students' executive attention显示文摘 | KUBESCH S WALK L SPITZER M | 2009 | Mind Brain Eud2009，3，： | 1 |
| 9 | Continuous nesting of Barn Owls in Illinois显示文摘 | JEFFERY W WALK TERRY L ESKER SCOTT A SIMPSON | 1999 | The Wilson Bulletin1999，111，4： | 1 |
| 10 | Phenol adsorption on GAC:application to the regeneration of GACs polluted with phenol carbon显示文摘 | MAGNE P L WALKE R | 1986 | Wat Sci Technol1986，24，2： | 1 |
| 11 | Nonparametric nearest neighbor based empirical portfolio selection strategies 显示文摘 | Gyorfi L Udina F Walk H | 2008 | Statistics and Decisions2008，26，2： | 1 |
| 12 | Resistance between stages of the Rhipicephalus appendiculatus (Acari:lxodidae) 显示文摘 | Walke A R Fletcher J D Todd L | 1990 | J Med Entomol1990，27，6： | 1 |
| 13 | Managerial Per- formance, Tobin's Q and the Gains from Successful Tender Offers 显示文摘 | LANG L STULZ R WALKING R | 1989 | Journal of Financial Economics1989，，24： | 1 |
| 14 | A Test of the Free Cash Flow Hypothesis: The Case of Bidder Returns显示文摘 | LANG L H P STULZ R M R A WALKING | 1991 | Journal of Financial Economics1991，29，2： | 1 |
| 15 | The usefulness of the detection of GSTP1 methylation in urine as a biomarker in the diagnosis of prostate cancer 显示文摘 | Woodson K O' Reilly K J Hanson J C Nelson D Walk E L Tangrea J A | 2008 | J Urol2008，179，： | 1 |
| 16 | The usefulness of the detection of GSTP1 methylation in urine as a biomarker in the diagnosis of prostate eancer显示文摘 | Woodson K O'Reilly K J Hanson J C Nelson D Walk E L Tangrea J A | 2008 | J Urol2008，179，： | 1 |
| 17 | Range-doppler imaging of rotating objects显示文摘 | Walk J L | 1980 | IEEE Transactions on Aerospace and Electronic Systems1980，16，1： | 1 |
| 18 | influence of lime- stone and phytase on broiler performance,gastrointestinal pH, and apparent ileal nutrient digestibility显示文摘 | Walk C L Bedford M R McElroy A P | 2012 | Poult Sci2012，91，6： | 1 |
| 19 | Influence of a microbial phytase and zinc oxide on young pig growth performance and serum minerals显示文摘 | Walk C L Srinongkote S Wilcock P | 2013 | Journal of Animal Science2013，91，1： | 1 |
| 20 | Microalgae as bioreactors 显示文摘 | Tara L Walke R Purton S | 2005 | Plant Cell Rep2005，24，： | 1 |
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