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| 1 | Evaluating ischemic stroke with diffusion tensor imaging显示文摘Objective:In recent years,diffusion tensor imaging (DTI) has emerged as a promising tool to study ischemic stroke. The aim of this study is to evaluate the anisotropic changes of cerebral white matter tracks in patients with ischemic stroke using DTI,and investigate the correlation between corticospinal tract damage and muscle strength in such patients during acute ischemia.Method:9 patients with acute ischemic stroke and 9 healthy subjects were examined with T1 weighted magnetic resonance imaging (MRI),T2 weighted MRI and DTI. Fractional anisotropy (FA) was measured and the three-dimensional fibrous band images of bilateral corticospinal tracts were reconstructed. The muscle strength of the affected hand was assessed by Brunnstorm standard[1],which is an internationally recognized measure of movement in hemiplegic patients.Results:①In the control group,there was no significant difference in FA between the bilateral corticospinal tracts,but FA in different white matter structure of the same side was significantly different (t=3.12,P < 0.05). FA of posterior limb of internal capsule was higher than that of knee and anterior limb of internal capsule,FA of anterior limb of internal capsule was the lowest. while in the patient group,FA of the infarcted sites was significantly lower than the contralateral ones (t=5.570,P < 0.01). ②The ipsilateral corticospinal tract demonstrated continuous interruption and the loss of consistent anatomic structure. The involved severity of corticospinal tract had significant correlation with that of muscle strength of the ipsilateral hand (r=0.83,P < 0.01).Conclusion:This study shows that DTI can be used to investigate ischemic stroke and assess ischemic stroke-induced damage. The damaged severity of corticospinal tracts is correlated with that of muscle strength. | Ziqian Chen Ping Ni Youqiang Ye Hui Xiao Gennian Qian Shangwen Xu Jingliang Wang Xizhang Yang Jinhua Chen Zhenshan Shi Biyun Zhang | 2008 | 福州总医院学报2008，15，3： | 6 |
| 2 | Zanthoxylum-specific whole genome duplication and recent activity of transposable elements in the highly repetitive paleotetraploid Z.bungeanum genome显示文摘Zanthoxylum bungeanum is an important spice and medicinal plant that is unique for its accumulation of abundant secondary metabolites,which create a characteristic aroma and tingling sensation in the mouth.Owing to the high proportion of repetitive sequences,high heterozygosity,and increased chromosome number of Z.bungeanum,the assembly of its chromosomal pseudomolecules is extremely challenging.Here,we present a genome sequence for Z.bungeanum,with a dramatically expanded size of 4.23 Gb,assembled into 68 chromosomes.This genome is approximately tenfold larger than that of its close relative Citrus sinensis.After the divergence of Zanthoxylum and Citrus,the lineage-specific whole-genome duplication event q-WGD approximately 26.8 million years ago(MYA)and the recent transposable element(TE)burst~6.41 MYA account for the substantial genome expansion in Z.bungeanum.The independent Zanthoxylum-specific WGD event was followed by numerous fusion/fission events that shaped the genomic architecture.Integrative genomic and transcriptomic analyses suggested that prominent speciesspecific gene family expansions and changes in gene expression have shaped the biosynthesis of sanshools,terpenoids,and anthocyanins,which contribute to the special flavor and appearance of Z.bungeanum.In summary,the reference genome provides a valuable model for studying the impact of WGDs with recent TE activity on gene gain and loss and genome reconstruction and provides resources to accelerate Zanthoxylum improvement. | Shijing Feng Zhenshan Liu Jian Cheng Zihe Li Lu Tian Min Liu Tuxi Yang Yulin Liu Yonghong Liu He Dai Zujun Yang Qing Zhang Gang Wang Jisen Zhang Huifeng Jiang Anzhi Wei | 2021 | Horticulture Research2021，8，1： | 5 |
| 3 | xperimental investigation on cumulative propagation of thin film buckling under cyclic load显示文摘As instrument technology is needed for rapid determination of the smaller,thinner and lighter specimens,more stringent demands are related to thin films such as micro-electro-mechanical systems(MEMS),dielectric coatings and electronic packaging.Therefore,the requirement for testing platforms for rapidly determine the mechanical properties of thin films is increasing.Buckling of a film/substrate system could offer a variety of applications,ranging from stretchable electronics to micro-nanoscale metrology.In this paper,a fatigue-loading device has been designed to make the cyclic loading available for investigating the cumulative propagation of thin film buckling.The straight side buckling of thin compressed titanium film with the thickness of 50 nm deposited on organic glass substrates is investigated by using an optical microscope.The cumulative buckling propagation under the cyclic loading of a sequence of peak compression with the frequency 1 Hz is recorded by CCD camera.The buckling extension lengths are calculated by digital image measurement technology. | WANG ShiBin JIA HaiKun LI LinAn SUN Heng CUI DiQiang GUO ZhenShan XUE XiuLi | 2011 | Science China(Technological Sciences)2011，54，6： | 4 |
| 4 | Review of Rapid Transformation of Floodplain Wetlands in Northeast China: Roles of Human Development and Global Environmental Change显示文摘Northeast China is the region with the largest area of wetlands in China. The Sanjiang Plain and the Songnen Plain are large freshwater marsh distribution regions that are affected by climate warming and by the increasing frequency and density of extreme weather and are the regions most subject to disturbances by human activities in Northeast China. The wetlands of the Sanjiang Plain and the Songnen Plain have shrunk severely in the past 60 years, and wetland functions have been reduced substantially because of climate change, unreasonable land use, fire episodes, engineering and construction works and urbanization. Large-scale agricultural development started in the 1950 s has been the most important driving factor for wetland loss and degradation in the Sanjiang Plain. Water shortage has been the most important factor for degradation and fragmentation of wetlands in the Songnen Plain. To mitigate wetland degradation and better protect wetlands, special regulations, long-term mechanisms and technical support of wetland protection should be established. A wetland compensation program should be implemented, and technologies for increasing the adaptive capacity of wetlands should be developed. Moreover, it is most important to find the balanced threshold between agricultural development and wetland protection. | YU Xiaofei DING Shanshan ZOU Yuanchun XUE Zhenshan LYU Xianguo WANG Guoping | 2018 | Chinese Geographical Science2018，28，4： | 2 |
| 5 | The Distribut- ed Control and Data System in HT-7 Tokamak 显示文摘 | Luo Jiarong Wang Huazhong Ji Zhenshan | 2002 | IEEE Transac- tions on Nuclear Science2002，49，2： | 1 |
| 6 | The distributed control and data system in HT-7 tokamak显示文摘 | LUO JIARONG WANG HUAZHONG JI ZHENSHAN | 2002 | IEEE Transactions on Nuclear Science2002，49，2： | 1 |
| 7 | Optimization of ethanol-water extraction of lignans from flaxseed显示文摘 | ZHANG Zhenshan LI Dong WANG Lijun | 2007 | Separation and Purification2007，57，1： | 1 |
| 8 | Catalytic transfer hydrogenolysis of C–O bonds in lignin model compounds without arene hydrogenation显示文摘The shortage of resources and the destruction of the environment have caused serious resource and environmental problems shared by all countries around the world. As a ubiquitous renewable resource, biomass has great prospects for replacing fossil energy and attracted attention from the society. The use of catalytic approach to transform biomass into high-value chemicals is an effective way to use biomass efficiently. In this work, Nisupported catalysts has been developed for the selective cleavage of C–O bonds in lignin model compounds with 2-propanol as the hydrogen source solvent. Among these catalysts, it was indicated that zirconium phosphate(Zr P)-supported Ni catalysts were highly efficient and recyclable for alkyl-aryl ether(α-O-4 and β-O-4) cleavage in lignin model compounds. The further investigation demonstrated that the transfer hydrogenolysis of the C–O bond is highly selective, which afforded phenols and aromatics as dominant products without the products arising from hydrogenation of aromatic rings. Through a series of characterization of the catalyst, it was demonstrated that the medium strong acid sites of the Zr P support promoted the cleavage of alkyl-aryl ethers(α-O-4 and β-O-4),and Br?nsted acid sites favored for achieving high selectivity toward C–O bond cleavage. Additionally, Ni(0) sites on the Zr P catalysts were responsible for the catalytic transfer hydrogenolysis. | Kai Cui Xiuge Zhao Qingpo Peng Honghui Gong Xinjia Wei Jiajia Wang Manyu Chen Zhenshan Hou | 2022 | Green Chemical Engineering2022，3，1： | 1 |
| 9 | Optimizationof ethanol-water extraction of lignans from flaxseed显示文摘 | Zhang Zhenshan Li Dong Wang Lijun | 2007 | Sepa-ration and Purification Technology2007，57，： | 1 |
| 10 | Resource prediction and assessment based on 3D/4D big data modeling and deep integration in key ore districts of North China显示文摘The North China district has been subjected to significant research with regard to the ore-forming dynamics,processes,and quantitative forecasting of gold deposits;it accounts for the highest number of gold reserves and annual products in China.Based on the top-level design of geoscience theory and the method adopted by the National Key R&D Project(deep process and metallogenic mechanism of North China Craton(NCC)metallogenic system),this paper systematically collects and constructs the geoscience data(district,camp,and deposit scales)in four key gold districts of North China(Jiaojia-Sanshandao,Southern Zhaoping,Wulong,and Qingchengzi).The settings associated with the geological dynamics of gold deposits were quantitatively and synthetically analyzed,namely:NCC destruction,metallogenic events,genetic models,and exploration models.Three-dimensional(3D)and four-dimensional(4D)geological modeling was performed using the big data on the districts,while the district-scale 3D exploration criteria were integrated to construct a quantitative exploration model.Among them,FLAC3D modelling and the Geo Cube software(version 3.0)were used to implement the numerical simulation of the 3D geological models and the constraints of the fluid saturation parameters of the Jiaojia fault to reconstruct the 4D fault structure models of the Jiaojia fault(with a depth of 5000 m).Using Geo Cube3.0,multiple integration modules(general weights of evidence(Wof E),Boost Wof E,Fuzzy Wof E,Logistic Regression,Information Entropy,and Random Forest)and exploration criteria were integrated,while the C-V fractal classification of A,B and C targets in four districts was carried out.The research results are summarized in the following four areas:(1)Four gold districts in the study area have more than three targets(the depth is 3000 m),and the class A,B and C targets exhibit a good spatial correlation with gold bodies that are controlled by mining engineering at depths greater than 1000 m.(2)The Boost Wof E method was used to identify the target optimization in 3D spaces(at depths of 3000–5000 m)of the Jiaojia-Sanshandao,Southern Zhaoping,and Wulong districts.(3)The general Wof E method is based on the Bayesian theory in 3D space and provides robust integration and target optimization that are suitable for the Jiaojia-Sanshandao and Southern Zhaoping districts in the Jiaodong area;it can also be applied to the Wulong district in the Liaodong area using a quantitative genetic model and an exploration model.Random forest is a multi-objective integration and target optimization method for 3D spaces,and it is suitable for the complex exploration model in the Qingchengzi district of the Liaodong area.The genetic model and exploration criteria associated with the exploration model of the Qingchengzi district were constrained by the common characteristics of the gold fault structure,magmatic rock emplacement in North China,and the strata fold and interlayer detachment structure.(4)Based on the gold reserves and the 3D block unit model of the Sanshandao gold deposit in the Jiaojia-Sanshandao district,the gold contents of the 3D block units in class A and B targets of the ore concentration were estimated to be 65.5%and 25.1%,respectively.The total Au resources of the optimized targets below a depth of 3000 m were 3908 t(including 1700 t reserves),and the total Au resources of the targets at depths from 3000 to 5000 m were 936 t.The study shows that the deep gold deposits in the four gold districts of North China exhibit a strong'transport-deposition'spatial correlation with potential targets.These'transport-deposition'spatial models represent the tectonic-magmatic-hydrothermal activities of the metallogenic system associated with the NCC destruction events and indicate the Au enrichment zones. | Gongwen WANG Zhiqiang ZHANG Ruixi LI Junjian LI Deming SHA Qingdong ZENG Zhenshan PANG Dapeng LI Leilei HUANG | 2021 | Science China Earth Sciences2021，64，9： | 1 |
| 11 | Ultrasound- assisted extraction of oil from flaxseed显示文摘 | ZHANG Zhenshan WANG Lijun LI Dong | 2008 | Separation and Purification Technology2008，62，1： | 1 |
| 12 | Optimization of ethanol-water extraction of lignans from flaxseed显示文摘 | ZHANG Zhenshan LI Dong WANG Lijun | 2007 | Separation and Purification Technology2007，57，： | 1 |
| 13 | EMD analysis of solar insolation显示文摘 | Lin Zhenshan Wang Shuguang | | 0，，： | 1 |
| 14 | Ultrasound-assistedextraction of oil from flaxseed显示文摘 | ZHANG Zhenshan WANG Lijun LI Dong | 2008 | Separation and Purification Technology2008，62，1： | 1 |
| 15 | Ultrasound-assis- ted extraction of oil from flaxseed显示文摘 | Zhang Zhenshan Wang Lijun Li Dong | 2008 | Separation and Purification Technology2008，62，1： | 1 |
| 16 | Functionalized Poly(ethylene glycol)-Stabilized Palladium Nanoparticles as an Efficient Catalyst for Aerobic Oxidation of Alcohols in Supercritical Carbon Dioxide/Poly(ethylene glycol) Biphasic Solvent System显示文摘 | Xiangrui Wang Hanmin Yang Bo Feng Zhenshan Hou Yu Hu Yunxiang Qiao Huan Li Xiuge Zhao | 2009 | Catalysis Letters (-)2009，，1： | 1 |
| 17 | Quantita-tive assessment of mineral resources by combining geostatisticsand fractal methods in the Tongshan porphyry Cu deposit(Chi-na)显示文摘 | Wang Gongwen Pang Zhenshan Boisvert J B | 2013 | Journal of Geochemical Exploration2013，134，： | 1 |
| 18 | Selective aerobic oxidation of styrene to benzaldehyde catalyzed by water - soluble palladium ( lI ) : Complex in water 显示文摘 | Feng Bo Hou Zhenshan Wang Xiangrui | 2009 | Green chemistry2009，11，9： | 1 |
| 19 | Ultrasound-assisted extraction of oil from flaxseed显示文摘 | ZHANG Zhenshan WANG Lijun LI Dong | | 0，，01： | 1 |
| 20 | Complete mill simulation of the roiling process of 1 660 mm hot strip continuous mills 显示文摘 | WANG Yingrui CUI Zhenshan WANG Yingjie | 2004 | Journal of Material ScienceTechnology2004，20，6： | 1 |
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