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33篇 您的检索式:作者名="WATSON G O"
    题名 作者 年代 出处 被引量
1Cytoplasmic expression of p27^(kip1) is associated with a favourable prognosis in colorectal cancer patients显示文摘AIM: To evaluate the prognostic significance of p27kip1 in colorectal cancer patients. METHODS: Cytoplasmic and nuclear p27kip1 expression was evaluated in 418 colorectal cancers using tissue microarrays. Data were associated with known patient and tumor variables and long-term patient outcomes, providing further insight into the mechanisms by which p27kip1 may influence tumor development. RESULTS: Nuclear and cytoplasmic p27Kip1 expressions were detected in 59% and 19% of tumors respectively. Cytoplasmic p27Kip1 was almost invariably associated with positive nuclear p27Kip1 expression. Neither case correlat- ed with known clinical or pathological variables, includ- ing tumor stage, grade or extramural vascular invasion. Furthermore, nuclear p27kip1 expression had no impact on survival. However, we identified a significant correla- tion between expression of cytoplasmic p27kip1 and longer disease-specific survival times. On multivariate analysis, TNM stage and extramural vascular invasion were highly significant independent prognostic factors, with positive cytoplasmic p27 expression showing a trend towards im- proved patient survival (P = 0.059).CONCLUSION: These findings support the recent evi- dence that cytoplasmic p27kip1 has a distinct and impor- tant biological role that can influence tumor outcome.Nicholas FS Watson Lindy G Durrant John H Scholefield Zahra Madjd Duncan Scrimgeour Ian Spendlove Ian O Ellis Poulam M Patel 2006World Journal of Gastroenterology2006,12,39:3
2Kinetics of allergen-induced airway eosinophilic cytokine production and airway inflammation显示文摘GAUVREAU G M WATSON R M O'BYRNE P M 1999Am J Respir Crit Care Med1999,160,2:1
3Tackling antibiotic resistance显示文摘Bush K Courvalin P Dantas G Davies J Eisenstein B Huovinen P Jacoby GA Kishony R Kreiswirth BN Kutter E Lerner SA Levy S Lewis K Lomovskaya O Miller JH Mobashery S Piddock LJ Projan S Thomas CM Tomasz A Tulkens PM Walsh TR Watson JD Witkowski J Witte W Wr 0,,:1
4Phytotoxicity of quassinoids : Physi- ological responses and structural requirements显示文摘Dayan F E Watson S B Galindo J C G Herndndez A D J McChesney J D Duke S O 1999Pesticide Biochemistry and Physiology1999,65,1:1
5显示文摘Cahill D G Watson S K Pohl R O 1992Physical Review B1992,46,10:1
6Integrated pest management of two-spotted mite Tetranychus urtieae on greenhouse roses using petroleum spray oil and the predatory mite Phytoseiulus persimilis显示文摘NICETIC O WATSON D M BEATTIE G A C MEATS A ZHENG J 2001Experimental and Applied Acarology2001,25,:1
7Characterization of Fine Particulate Emissions from Casting Processes 显示文摘Chang M C O Chow J C Watson J G 2005Aerosol Sci Technol2005,39,10:1
8显示文摘Cahill D G Watson S K Pohl R O 1992Physical Review B1992,46,10:1
9A mesoscale phytoplankton bloom in the polar Southern Ocean stimulated by iron fertilization 显示文摘Boyd P W Watson A J Law C S Abraham E R Trull T Murdoeh R Bakker D C E Bowie A R Buesseler K O Chang H Charette M Croot P Downing K Frew R Gall M Hadfield M Hall J Harvey M Jameson G LaRoche J Liddicoat M Ling R Maldonado M T McKay R M Nodder S Pickmere S Pridmore R Rintoul S Sail K Sutton P Strzepek R Tanneberger K Turner S Waite A Zeldis J 2000Nature2000,407,6805:1
10Understand- ing the p-type conduction properties of the transparent con- ducting oxide CuBO2: a density functional theory analysis 显示文摘SCANLON D O WALSH A WATSON G W 2009Chemistry of Materials2009,21,19:1
11Mechanical stretch alters human bladder smooth muscle phenotype显示文摘GALVIN D WATSON R W G O' NEILL A J 2002Eur Urol Suppl2002,1,1:1
12Factors Deter- mining Relations between Stand Age and Catchment Water Balance in Mountain Ash Forests显示文摘Vertessy R A Watson F G R O'Sullivan S K 2001Forest Ecology and Management2001,143,:1
13Gas exchange responses of two Eucalyptus species to salinity and water logging显示文摘Vander Moezel P G Watson L E Bell O T 1989Tree Physiology1989,,5:1
14Nitrogen in plant parts of seven wheat varieties at successive stages of development显示文摘McNeal F H Boat Wright G O Berg M A Watson C A 1968Crop Science1968,8,:1
15Assessment of long-term effects of transient anoxia on metabolic activity of rat hippocampal slices using triphe-nyltetrazolium chloride 显示文摘Watson G B Lopez O T Charles V D 1994J Neurosci Methods1994,53,2:1
16Factors Determining Relations Between Stand Age and Catchment Water Balance in Mountain Ash Forests 显示文摘VERTESSY R A WATSON F G R O'SULLIVAN S K 2001For- est Ecology and Management2001,143,1:1
17Bond lengths in organic compounds 显示文摘Allen F H Kennard O Watson D G 1987J Chem Soc Perkin Tram 21987,,:1
18Variability in ben- thic respiration in three southeastern Australian lowland riv- ers 显示文摘Rees G N Bowen P M Watson G O 2005 2005River Research and Applications2005,21,10:1
19Understanding the p- type conduction properties of the transparent conducting oxide CuBO2: A density functional theory analysis 显示文摘Scanlon D O Walsh A Watson G W 2009Chem Mater2009,21,19:1
20Variability in benthic respiration in three southeastern Australian lowland rivers 显示文摘REES G N BOWEN P M WATSON G O 2005River Research and Applications2005,21,10:1
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