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| 1 | Identification of a combination of SNPs associated with Graves' disease using swarm intelligence显示文摘Graves' disease,the production of thyroid-stimulating hormone receptor-stimulating antibodies leading to hyperthyroidism,is one of the most common forms of human autoimmune disease.It is widely agreed that complex diseases are not controlled simply by an individual gene or DNA variation but by their combination.Single nucleotide polymorphisms(SNPs),which are the most common form of DNA variation,have great potential as a medical diagnostic tool.In this paper,the P-value is used as a SNP pre-selection criterion,and a wrapper algorithm with binary particle swarm optimization is used to find the rule for discriminating between affected and control subjects.We analyzed the association between combinations of SNPs and Graves' disease by investigating 108 SNPs in 384 cases and 652 controls.We evaluated our method by differentiating between cases and controls in a five-fold cross validation test,and it achieved a 72.9% prediction accuracy with a combination of 17 SNPs.The experimental results showed that SNPs,even those with a high P-value,have a greater effect on Graves' disease when acting in a combination. | WEI Bin PENG QinKe ZHANG QuanWei LI ChenYao | 2011 | Science China(Life Sciences)2011，54，2： | 6 |
| 2 | Effects on Growth Performance and Feed Digestibility of Hainan Black Pigs by Adding Lysine in Low Protein Diet显示文摘[Objective] The paper was to study the effects on growth performance and feed digestibility of Hainan black pigs by adding lysine in low protein diet.[Method] A total of 36 Hainan black pigs with the body weight of(46.34 ±3.06) kg were randomly divided into three groups:control group(protein level 15%,lysine level 0.83%),experimental group I(protein level 13%,0.83%),and experimental group II(protein level 13%,lysine level 1.03),each group had three replicates of four pigs.The trial lasted 35 d.[Result] The growth performance of Hainan black pig in group II had no significant difference with that in control group(P>0.05).The apparent digestibility of crude protein and phosphorus of Hainan black pigs in Group II increased significantly(P<0.05),which were increased by 10.08% and 11.85% respectively compared to the control group;the apparent digestibility of calcium was increased,but the difference was not significant(P>0.05).[Conclusion] It will not reduce the growth performance of Hainan black pig when the protein level of diet is reduced by 2% and the lysine level is increased to 1.03%.It is recommended that the diet can be used in the production of Hainan black pig. | Wei Limin Liu Quanwei Sun Ruiping Zheng Xinli Wang Feng Tan Shuyi Huang Lili Xing Manping | 2018 | Animal Husbandry and Feed Science2018，10，2： | 4 |
| 3 | Effect of Pelleted Total Mixed Ration on Production Performance and Serum Biochemical Index of Growing Hainan Black Goats显示文摘[Objective] The paper was to investigate effects of pelleted total mixed ration on production performance and serum biochemical index of growing Hainan black goats.[Method] Twenty-four growing Hainan black goats with the same genetic backgrounds and similar initial weight of(10.05±0.049) kg were randomly assigned into two treatments, and supplied with Juncao + concentrate(control group), pelleted total mixed ration(experimental group), respectively. The trial lasted 50 d.[Result] The final weight, daily gain and feed intake of experimental group were significantly higher than those of control group(P<0.05), but the feed/gain ratio of experimental group was markedly lower than that of control group(P<0.05). Compared with the control group, the gross profit of experimental group significantly increased( P <0.05).[Conclusion] Pelleted total mixed ration led to better production performance of growing Hainan black goat. | Liu Quanwei Wang Feng Wei Limin Huang Lili Sun Ruiping Xing Manping Zheng Xinli | 2019 | Animal Husbandry and Feed Science2019，11，1： | 4 |
| 4 | Single channel signal component separation using Bayesian estimation显示文摘A Bayesian estimation method to separate multicomponent signals with single channel observation is presented in this paper. By using the basis function projection, the component separation becomes a problem of limited parameter estimation. Then, a Bayesian model for estimating parameters is set up. The reversible jump MCMC (Monte Carlo Markov Chain) algorithmis adopted to perform the Bayesian computation. The method can jointly estimate the parameters of each component and the component number. Simulation results demonstrate that the method has low SNR threshold and better performance. | Cai Quanwei Wei Ping Xiao Xianci | 2007 | Journal of Systems Engineering and Electronics2007，18，1： | 4 |
| 5 | Effects of Dietary Crude Fiber Levels on Growth Performance and Serum Biochemical Index of Dingan Geese Aged from 35 to 70 Days显示文摘[Objective] The study was carried out to investigate the effects of dietary crude fiber on growth performance and serum biochemical in-dex of Dingan geese aged from 35 to 70 days.[Method] A total of 120 Dingan geese on day 28 with the same genetic background and similar initial weight(1 384.83.73±0.76 g) were randomly assigned into 3 groups, with 4 replicates per group and 10 geese per replicate. Geese were fed the diets containing 4.29%, 5.29% and 6.29 % crude fiber, respectively. The experiment lasted 35 d.[Result] Final weight and daily gain of 5.29 %CF group were significantly higher than those of 6.29 % CF group(P<0.05);Feed intake was markedly higher than those of 4.29% and 6.29 % CF groups(P<0.05);Feed gain ratio was significantly lower than that of 6.29 % CF group(P<0.05). Compared with 4.29% and 6.29 % CF groups, serum albumin concentrations of 5.29 % CF group increased significantly(P<0.05), while serum total protein and globin contents were higher(P>0.05), but serum uric acid level was lower(P>0.05).[Conclusion] 5.29 % crude fiber could lead to higher growth performance of Dingan geese. | Liu Quanwei Wang Feng Wei Limin Lin Dajie Xing Manping Yang Shaoxiong Sun Ruiping Ye Baoguo | 2019 | Animal Husbandry and Feed Science2019，11，1： | 3 |
| 6 | Effects of Dietary Concentrate to Forage Ratios on Production Performance and Serum Biochemical Indicators in Post-fattening Hainan Yellow Cattle显示文摘[Objective]The paper was to investigate the effects of dietary concentrate to forage ratios on production performance and serum bio-chemical indicators of post-fattening Hainan Yellow Cattle.[Method]Sixteen Hainan Yellow Cattles with the same genetic backgrounds and similar initial weight of(242.22 ±0.71 kg) were randomly divided into four treatments.Cattles were fed with diets of different concentrate to forage ratios(20:80, group Ⅰ;30:70, Group Ⅱ;40:60, group Ⅲ;50:50, group Ⅳ).The trial lasted 62 d.[Result]The daily gain in experimental group Ⅳ was significantly higher than that in experimental group Ⅱ(P<0.05), but the feed gain ratio in experimental group Ⅳ was lower than those in other ex-perimental groups(P>0.05).The feed intake in experimental group Ⅳ was also markedly higher than those in experimental groups Ⅰ and Ⅱ(P<0.05).Compared with the experimental group Ⅱ, the gross profit of experimental group Ⅳ was significantly promoted(P<0.05).The alanine aminotransferase and aspartate aminotransferase activities in experimental group Ⅱ were markedly higher than those in experimental groups Ⅰ, Ⅲ and Ⅳ.[Conclusion]When the dietary concentrate to forage ratios was 50∶50, the production performance of post-fattening Hainan Yellow Cattle was better. | Wang Feng Wei Limin Zheng Xinli Liu Hailong Sun Ruiping Chao Zhe Huang Lili Fu Liang Liu Quanwei | 2020 | Animal Husbandry and Feed Science2020，12，1： | 3 |
| 7 | Single-channel blind separation of overlapped multicomponents based on energy operator显示文摘A method utilizing single channel recordings to blind separate the multicomponents overlapped in both time and frequency domains is proposed in this paper. The main idea of the method is based on using the energy operator and differential energy operator to estimate instantaneous frequencies and amplitudes of each component and then to reconstruct these components. This method, due to the good time resolution of the energy operator and differential energy operator, as well as the very low computational complexity, is very useful in real time processing and practical applications. Simulation results demonstrated the effciency of this method. | CAI QuanWei, WEI Ping & XIAO XianCi College of Electronic Engineering, University of Electronic Science and Technology of China, Chengdu 610054, China | 2010 | Science China(Information Sciences)2010，53，1： | 3 |
| 8 | Effect of Pelleted Total Mixed Ration of Different Particle Sizes on Production Performance and Serum Biochemical Index of Fattening Hainan Black Goats显示文摘[Objective] The paper to investigate the effects of pelleted total mixed ration of different particle size on production performance and serum biochemical index of fattening Hainan black goats.[Method] Thirty-six fattening Hainan black goats with the same genetic backgrounds and similar initial weight of(19.02±0.22) kg were randomly divided into three treatments. Goats were fed with Juncao+concentrate(control group), pel-leted total mixed ration I(particle size 6 mm, experimental group I) and II(particle size 5 mm, experimental group II), respectively. The trial lasted 45 d.[Result](1) The final weight and daily gain of experimental group II were significantly higher than those of control group( P<0.05), and the daily gain of experimental group II was also higher than that of experimental group I(P<0.05);the feed intake of experimental group II was markedly higher than that of control group(P<0.05), but was significantly lower than that of experimental group I(P<0.05). The feed/gain ratio of experimental group II was significantly lower than those of control group and experimental group I(P<0.05).(2) The feed gain cost of experimental group II was markedly lower than that of control group(P<0.05), but the gross profit was significantly higher than those of control group and experimental group I(P<0.05).(3) Compared with the control group, the serum total protein content of experimental group II increased markedly( P<0.05) while the urea nitrogen level decreased(P>0.05).[Conclusion] The pelleted total mixed ration with the particle size of 5 mm obtained better fattening ef-fect, and obviously improved the serum total protein level. | Liu Quanwei Wei Limin Wang Feng Tan Shuyi Sun Ruiping Huang Lili Zheng Xinli | 2019 | Animal Husbandry and Feed Science2019，11，1： | 2 |
| 9 | Clinical time course of COVID-19, its neurological manifestation and some thoughts on its management显示文摘Coronavirus disease-2019(COVID‐19)has become a global pandemic.COVID-19 runs its course in two phases,the initial incubation phase and later clinical symptomatic phase.Patients in the initial incubation phase often have insidious clinical symptoms,but they are still highly contagious.At the later clinical symptomatic phase,the immune system is fully activated and the disease may enter the severe infection stage in this phase.Although many patients are known for their respiratory symptoms,they had neurological symptoms in their first 1-2 days of clinical symptomatic phase,and ischaemic stroke occurred 2 weeks after the onset of the clinical symptomatic phase.The key is to prevent a patient from progressing to this severe infection from mild infection.We are sharing our experience on prevention and management of COVID-19. | Yifan Zhou Wei Li David Wang Ling Mao Huijuan Jin Yanan Li Candong Hong Shengcai Chen Jiang Chang Quanwei He Mengdie Wang Bo Hu | 2020 | Stroke & Vascular Neurology2020，5，2： | 2 |
| 10 | Comparability in geomorphic evolution of the three rivers in the northern Longitudinal Range-Gorge Region: Evidence of statistic relationships between geomorphic parameters and analyses of cause of formation显示文摘 | WANG Suiji WU Shaohong HE Daming DAI Erfu ZHOU Changhai WEI Quanwei | 2006 | Chinese Science Bulletin2006，51，B11： | 2 |
| 11 | Slaughtering Performance and Meat Quality of Hainan Black Goat and Its Hybrid Offsprings with Nubian Black Goat显示文摘In order to compare the slaughter performance and meat quality of Hainan black goats and hybrid offsprings of Nubian Black Goat and Hainan Black Goat, six 7-month-old Hainan black goats and six hybrid offsprings were selected to determine slaughter performance and muscle quality. The results showed that hybridization of Nubian black goat and Hainan black goat significantly improved the production performance and slaughter performance of hybrid offsprings (P>0.05). The meat quality of F1 hybrid black goat had no significant difference with that of Hainan black goat except for the hardness and elasticity (P<0.05). Therefore, the crossbred progenies of Nubian black goat and Hainan black goat have advantages in meat yield and meat performance, and the main meat quality indexes are not significantly different, which meets the market requirements for high-yield and high-quality hybrid combinations, and can be used for cross promotion. | Wei Limin Sun Ruiping Liu Yan Liu Ruina Liu Quanwei Zheng Xinli Wang Feng Huang Lili Xing Manping | 2019 | Animal Husbandry and Feed Science2019，11，2： | 2 |
| 12 | Effects of Crude Fiber Levels on Production Performance, Organ Index and Serum Biochemical Parameters of Dingan Geese Aged from 1 to 28 Days显示文摘[Objective]The paper was to investigate the effects of dietary crude fiber level on production performance,organ index and serum biochemical parameters of Dingan geese aged from 1 to 28 days.[Method]A total of 144 1-day-old Dingan geese with the same genetic background and similar initial weight(88.75±0.21g)were randomly assigned into 3 groups with 4 replicates per group and 12 geese per replicate,and fed with the diets containing 2.56%,3.52% and 4.48% crude fiber,respectively.The trial lasted 28 d.[Result]1)The final weight and daily gain of 3.52% CF group were significantly higher than those of 2.56% CF group(P<0.05);the feed/gain ratio was markedly lower than that of 2.56% CF group(P<0.05).2)The slaughter rate,semi-eviscerated rate and leg muscle rate of 3.52% CF group were higher than those of 2.56% and 4.48% CF groups(P>0.05).3)As the dietary crude fiber levels rose,the abdominal fat rate showed a downward trend(P>0.05).4)The liver index of 3.52% CF group was significantly higher than that of 2.56% CF group(P<0.05).4)Compared with 2.5%and 4.48% CF groups,the serum albumin concentrations of 3.52% CF group markedly increased(P<0.05),the serum total protein and globin contents were higher(P>0.05),but the serum uric acid level was lower(P>0.05).[Conclusion]When the crude fiber level was 3.52%,the production performances of Dingan geese aged from 1 to 28 days were better,and the liver index and serum albumin level could be obviously improved. | Liu Quanwei Wei Limin Wang Feng Lin Dajie Xing Manping Yang Shaoxiong Sun Ruiping Ye Baoguo | 2019 | Animal Husbandry and Feed Science2019，11，3： | 1 |
| 13 | A Digital Modulation Recognition Method显示文摘 | Cai Quanwei Wei Ping Xiao Xianci | 2004 | IEEE Trams on Communications2004，48，07： | 1 |
| 14 | Simulation and optimization of a double THGEM detector显示文摘A double thick GEM (THGEM) detector with thin THGEM foils and small holes was constructed. In order to optimize the operation parameters of the detector, a simulation study of the detector was carried out using ANSYS and Garfield program. Some important characteristics, including primary electron transparency, avalanche development and the secondary electron loss were calculated. Parameters, such as electric field and gas choice were optimized. | WANG Xiaohu WEI Tao LONG Jidong LI Quanwei ZHANG Linwen | 2013 | Nuclear Science and Techniques2013，24，1： | 1 |
| 15 | A blind separation method of overlapped multi-components based on time varying AR model显示文摘A method utilizing single channel recordings to blindly separate the multicompo- nents overlapped in time and frequency domains is proposed in this paper. Based on the time varying AR model, the instantaneous frequency and amplitude of each signal component are estimated respectively, thus the signal component separa- tion is achieved. By using prolate spheroidal sequence as basis functions to ex- pand the time varying parameters of the AR model, the method turns the problem of linear time varying parameters estimation to a linear time invariant parameter es- timation problem, then the parameters are estimated by a recursive algorithm. The computation of this method is simple, and no prior knowledge of the signals is needed. Simulation results demonstrate validity and excellent performance of this method. | CAI QuanWei WEI Ping XlAO XianCi | 2008 | Science in China(Series F)2008，51，1： | 1 |
| 16 | A digital modu-lation recognition method显示文摘 | Ping Wei Xianci Xiao | 2004 | IEEE Transion Com-munications2004，48，7： | 1 |
| 17 | Maternal stevioside supplementation improves intestinal immune function of chicken offspring potentially via modulating gut microbiota and down-regulating the promoter methylation level of suppressor of cytokine signaling 1(SOCS1)显示文摘The intestinal immune function of chickens is limited during the early growing stage.Maternal nutritional intervention has been suggested to affect the innate immunity of offspring.The present study aimed to investigate the effects of maternal stevioside supplementation on the intestinal immune function of chicken offspring.A total of 120 Jinmao yellow-feathered breeder hens were fed a basal diet or a diet supplemented with 250 mg/kg stevioside for 5 weeks.During the last week,200 breeding eggs from each group were collected for incubation.After hatching,80 male offspring(40 chickens from each group)were randomly selected and fed the same basal diet for 28 d.In addition,90 well-shaped fertile eggs of non-treated breeder hens were incubated for the in ovo injection experiment.Steviol dissolved in 20%glycerol was injected at 7 d of incubation.The results showed that maternal stevioside supplementation could improve embryonic development,jejunal integrity and proliferation in the jejunal crypt(P<0.05).Maternal stevioside supplementation could also increase the innate transcription levels of cytokines and endotoxin tolerance-related factors in the jejunum of chicken offspring(P<0.05).At 28 d of age,the offspring following maternal stevioside supplementation exhibited higher jejunal secretory immunoglobulin A and serum interferons levels(P<0.05).A higher abundance of Lactobacillales induced by maternal stevioside supplementation was positively correlated with intestinal immunerelated factors(P<0.05).The in ovo injection with steviol did not alter either embryonic development or intestinal immune function of hatching chickens(P>0.05).Furthermore,maternal stevioside supplementation could induce hypo-methylation on the promoter region of suppressor of cytokine signaling 1(SOCS1).In conclusion,maternal stevioside supplementation could improve the intestinal immune function of chicken offspring potentially via modulating the gut microbiota and downregulating the promoter methylation level of SOCS1. | Jingle Jiang Lina Qi Quanwei Wei Fangxiong Shi | 2022 | Animal Nutrition2022，，3： | 1 |
| 18 | A Digital Modulation Recognition Method显示文摘 | Cai Quanwei Wei Ping Xiao Xianci | 2004 | IEEE Trans on Communications2004，38，07： | 1 |
| 19 | A Digital Modulation Recognition Method 显示文摘 | Quanwei Cai Ping Wei Xianci Xiao | 2004 | IEEE Trans on Communications2004，48，7： | 1 |
| 20 | Platycodon grandiflorus polysaccharide regulates colonic immunity through mesenteric lymphatic circulation to attenuate ulcerative colitis显示文摘Platycodon grandiflorus polysaccharide(PGP)is one of the main components of P.grandiflorus,but the mechanism of its anti-inflammatory effect has not been fully elucidated.The aim of this study was to evaluate the therapeutic effect of PGP on mice with dextran sodium sulfate(DSS)-induced ulcerative colitis(UC)and explore the underlying mechanisms.The results showed that PGP treatment inhibited the weight loss of DSS-induced UC mice,increased colon length,and reduced DAI,spleen index,and pathological damage within the colon.PGP also reduced the levels of pro-inflammatory cytokines and inhibited the enhancement of oxidative stress and MPO activity.Meanwhile,PGP restored the levels of Th1,Th2,Th17,and Treg cell-related cytokines and transcription factors in the colon to regulate colonic immunity.Further studies revealed that PGP regulated the balance of colonic immune cells through mesenteric lymphatic circulation.Taken together,PGP exerts anti-inflammatory and anti-oxidant effect and regulates colonic immunity to attenuate DSS-induced UC through mesenteric lymphatic circulation. | LIU Yang DONG Yahui SHEN Wei DU Jiahui SUN Quanwei YANG Ye YIN Denke | 2023 | Chinese Journal of Natural Medicines2023，21，4： | 0 |
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