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| 1 | Neuroimaging the brain-gut axis in patients with irritable bowel syndrome显示文摘AIM:To summarize and synthesize current literature on neuroimaging the brain-gut axis in patients with irritable bowel syndrome(IBS).METHODS:A database search for relevant literature was conducted using Pub Med,Scopus and Embase in February 2015.Date filters were applied from the year2009 and onward,and studies were limited to those written in the English language and those performed upon human subjects.The initial search yielded 797articles,out of which 38 were pulled for full text review and 27 were included for study analysis.Investigations were reviewed to determine study design,methodology and results,and data points were placed in tabular format to facilitate analysis of study findings across disparate investigations.RESULTS:Analysis of study data resulted in the abstraction of four key themes:Neurohormonal differences,anatomic measurements of brain structure and connectivity,differences in functional responsiveness of the brain during rectal distention,and confounding/correlating patient factors.Studies in this review noted alterations of glutamate in the left hippocampus(HIPP),commonalities across IBS subjects in terms of brain oscillation patterns,cortical thickness/gray matter volume differences,and neuroanatomical regions withincreased activation in patients with IBS:Anterio cingulate cortex,mid cingulate cortex,amygdala anterior insula,posterior insula and prefrontal cortex.A striking finding among interventions was the substantia influence that patient variables(e.g.,sex,psychologica and disease related factors)had upon the identification of neuroanatomical differences in structure and con nectivity.CONCLUSION:The field of neuroimaging can provide insight into underlying physiological differences that distinguish patients with IBS from a healthy population. | Kristen R Weaver Lee Anne B Sherwin Brian Walitt Gail D'Eramo Melkus Wendy A Henderson | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，2： | 8 |
| 2 | Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial显示文摘 | Wendy S Atkin Rob Edwards Ines Kralj-Hans Kate Wooldrage Andrew R Hart John MA Northover D Max Parkin Jane Wardle Stephen W Duffy Jack Cuzick | 2010 | The Lancet2010，，9726： | 4 |
| 3 | Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial显示文摘 | Wendy S Atkin Rob Edwards Ines Kralj-Hans Kate Wooldrage Andrew R Hart John MA Northover D Max Parkin Jane Wardle Stephen W Duffy Jack Cuzick | 2010 | 2010 (9726)2010，，9726： | 3 |
| 4 | Gynecologic oncologists involvement on ovarian cancer standard of care receipt and survival显示文摘AIM:To examine the influence of gynecologic oncolo-gists(GO) in the United States on surgical/chemotherapeutic standard of care(SOC), and how this translates into improved survival among women with ovarian cancer(OC).METHODS: Surveillance, Epidemiology, and End Result(SEER)-Medicare data were used to identify 11688 OC patients(1992-2006). Only Medicare recipients with an initial surgical procedure code(n = 6714) were included. Physician specialty was identified by linking SEER-Medicare to the American Medical Association Masterfile. SOC was defined by a panel of GOs. Multivariate logistic regression was used to determine predictors of receiving surgical/chemotherapeutic SOCand proportional hazards modeling to estimate the effect of SOC treatment and physician specialty on survival. RESULTS: About 34% received surgery from a GO and 25% received the overall SOC. One-third of women had a GO involved sometime during their care. Women receiving surgery from a GO vs non-GO had 2.35 times the odds of receiving the surgical SOC and 1.25 times the odds of receiving chemotherapeutic SOC(P < 0.01). Risk of mortality was greater among women not receiving surgical SOC compared to those who did [hazard ratio = 1.22(95%CI: 1.12-1.33), P < 0.01], and also was higher among women seen by non-GOs vs GOs(for surgical treatment) after adjusting for covariates. Median survival time was 14 mo longer for women receiving combined SOC. CONCLUSION: A survival advantage associated with receiving surgical SOC and overall treatment by a GO is supported. Persistent survival differences, particularly among those not receiving the SOC, require further investigation. | Sun Hee Rim Shawn Hirsch Cheryll C Thomas Wendy R Brewster Darryl Cooney Trevor D Thompson Sherri L Stewart | 2016 | World Journal of Obstetrics and Gynecology2016，5，2： | 3 |
| 5 | Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders显示文摘 | E Joanna Baxter Linda M Scott Peter J Campbell Clare East Nasios Fourouclas Soheila Swanton George S Vassiliou Anthony J Bench Elaine M Boyd Natasha Curtin Mike A Scott Wendy N Erber Anthony R Green | 2005 | The Lancet . 2005 (9464)2005，，： | 2 |
| 6 | Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial显示文摘 | Wendy S Atkin Rob Edwards Ines Kralj-Hans Kate Wooldrage Andrew R Hart John MA Northover D Max Parkin Jane Wardle Stephen W Duffy Jack Cuzick | 2010 | The Lancet . 2010 (9726)2010，，： | 2 |
| 7 | Diagnosis and management of bile leaks after blunt liver injary显示文摘 | Wendy L Wahl Mary-Margaret Brandt Mark R Hetnmila | 2005 | Surgery2005，138，4： | 1 |
| 8 | Holliday junction processing activity of the BLM-Topo Ⅲα-BLAF75 complex显示文摘 | WENDY B STEVEN R VALERIA B | 2007 | J Bioll Chem2007，282，31： | 1 |
| 9 | In vivo assessment of ductal carcinoma in situ grade: a model incorporating dynamic contrast-enha-need and diffusion-weighted breast MR imaging parameters 显示文摘 | Habib R Savannah CP Wendy BD | 2012 | Radi- ology2012，263，2： | 1 |
| 10 | Implanted fiberoblasts genetically engineered to produce BDNF prevent MPTP toxicity to dopaminergic neurons in the rat显示文摘 | David M Tara A Wendy R | 1994 | Proc Natl Acad Sci USA1994，91，： | 1 |
| 11 | Vasopressin: a new target for the treatment of heart failure显示文摘 | Craig R Lee Michael L Watkins J.Herbert Patterson Wendy Gattis Christopher M O'Connor Mihai Gheorghiade Kirkwood F Adams | 2003 | American Heart Journal2003，，1： | 1 |
| 12 | Alpha-tocopherol supplementation in healthy individuals reduces low - density lipoprotein oxidation but not atherosclerosis显示文摘 | Howard N Wendy J Peter R | | 0，，： | 1 |
| 13 | Collagenase pretreatment and the mitogenic effects of hepatocyte growth factor and transforming growth factor-α in adult rat liver 显示文摘 | Liu ML Wendy M Zarnegar R | 1994 | Hepatology1994，19，6： | 1 |
| 14 | Crystallization in polymorphic systems:the solution-mediated transformation ofβtoαglycine显示文摘 | Ferrari E S Davey R J Wendy I | 2003 | Cryst Growth Des2003，3，1： | 1 |
| 15 | Conformity to sex-typed norms, affect, and the self-concept显示文摘 | WENDY W P NIELS C MICHELLE R H | 1997 | Journal of Prsonality and Social Psychology1997，73，3： | 1 |
| 16 | Pregnancy outcome when both members of a couple have balanced translocations 显示文摘 | Stephanie A C Wendy R U Debra D | 1995 | Obstet Gynecol1995，85，5： | 1 |
| 17 | Minimal access thyroid surger- y : Technique and report of the first 25 case 显示文摘 | Jessica E Gosnell Wendy R | 2004 | Anz J Surg2004，74，： | 1 |
| 18 | Review of new guidelines for the management of glucocorticoid induced osteoporosis 显示文摘 | Swamy R Venuturupalli Wendy Sacks | 2013 | Current Osteoporosis Reports2013，11，4： | 1 |
| 19 | Determination of aristolochic acid in botanicals and dietary supplements by liquid chromatography with ultraviolet detection and by liquid chromatography/mass spectrometry: single laboratory validation confirmation显示文摘 | WILLIAM A Trujillo WENDY R Sorenson PAUL La Luzerne | 2006 | Journal of AOAC International2006，89，4： | 1 |
| 20 | Apolipoprotein A-I, cyclodextrins and liposomes as potential drugs for the reversal of atherosclerosis显示文摘 | Wendy J | 2000 | J Pharm Pharmacol2000，52，7： | 1 |
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