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| 1 | Management of diverticular disease is changing显示文摘结肠的憩室的疾病主要是人住在的疾病西洋化并且工业化国家。人住在工业化国家中的百分之六十个将开发结肠的憩室。它以前是稀罕的它发生在幼仔的 40 的年龄,而是对复杂并发症敏感的更多。在年龄 80,超过 65% 人有结肠的憩室。原因遗体不明确,却流行病的研究把它归因于饮食的纤维缺乏。憩室炎的原因仍然保持不明确,却新观察和假设建议它由于在肠墙中的慢性炎。肠休息和抗菌素的标准医药治疗仍然是推荐处理。然而,改变概念和新治疗 indicate 职业人员生命学可以是的反煽动性的代理人象 mesalamine 那样并且可能在弄短有用功课和也许阻止的复发。为为严重急性病的穿孔的标准外科疗法发展了以便二阶段的过程被推荐。另外, laparoscopic 外科证明了安全并且可以慢慢地成为选择的技术。 | Martin H Floch Jonathan A White | 2006 | World Journal of Gastroenterology2006，12，20： | 7 |
| 2 | Pyruvate-fortified resuscitation stabilizes cardiac electrical activity and energy metabolism during hypovolemia显示文摘AIM: To test the hypothesis that fluid resuscitation with Ringer's solution enriched with pyruvate(PR), a physiological antioxidant and energy substrate, affords protection of myocardial metabolism and electrophysiological performance superior to lactated Ringer's(LR) during hypovolemia and hindlimb ischemia-reperfusion.METHODS: Male domestic goats(25-30 kg) were exsanguinated to a mean arterial pressure of 48 ± 1 mm Hg. Right hindlimb ischemia was imposed for 90 min by applying a tourniquet and femoral crossclamp. LR or PR, infused iv, delivered 0.05 mmol/kg per minute L-lactate or pyruvate, respectively, from 30 min hindlimb ischemia until 30 min post-ischemia. Time controls(TC) underwent neither hemorrhage, hindlimb ischemia nor resuscitation. Goats were sacrificed and left ventricular myocardium biopsied at 90 min fluid resuscitation(n = 6 per group) or 3.5 h later(n = 9 LR, 10 PR, 8 TC).RESULTS: Myocardial 8-isoprostane content, phosphocreatine phosphorylation potential, creatine kinase activity, and heart rate-adjusted QT interval(QTc) vari- ability were evaluated at 90 min resuscitation and 3.5 h post-resuscitation. PR sharply lowered pro-arrhythmic QTc variability vs LR(P < 0.05); this effect persisted 3.5 h post-resuscitation. PR lowered myocardial 8-isoprostane content, a product of oxidative stress, by 39 and 37% during and 3.5 h after resuscitation, respectively, vs LR. Creatine kinase activity fell 42% post-LR vs TC(P < 0.05), but was stable post-PR(P < 0.02 vs post-LR). PR doubled phosphocreatine phosphorylation potential, a measure of ATP free energy state, vs TC and LR(P < 0.05); this energetic enhancement persisted 3.5 h post-resuscitation.CONCLUSION: By augmenting myocardial energy state and protecting creatine kinase activity, pyruvateenriched resuscitation stabilized cardiac electrical function during central hypovolemia and hindlimb ischemiareperfusion. | Hunaid A Gurji Daniel W White Besim Hoxha Jie Sun Albert H Olivencia-Yurvati Robert T Mallet | 2013 | World Journal of Critical Care Medicine2013，2，4： | 3 |
| 3 | “嘎拉”苹果显示文摘新育成的苹果品种嘎拉,底色米黄,具橙红色条纹,果实小到中型,突出特点是果肉松脆多汁,风味清爽。嘎拉的出现应归功于一位新西兰果树育种家J.H.Kidd的远见卓识。于1920年在他的Wairarapa果园就开始了苹果的杂交育种工作。他痛惜在新苹果品种中有食用品质下降的趋势,认为具有吸引力、甜果的北美栽培品种和风味好的英国品种间杂交,可育成理想的苹果品种。1931年,Kidd选出了有希望的基橙品种(Kidd’s Orange),并出售了其繁育权,由“桔苹”和“元帅”杂交育成。1930年后继续进行了杂交,获得了几百株“基橙”ד金冠”的杂种实生苗,很遗憾kidd先生未能完成新一代苹果品种的选择。1952年。 | A G White 王同坤 | 1991 | 河北果树1991，0，4： | 2 |
| 4 | Role of anti-stromal polypharmacy in increasing survival after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma显示文摘AIM: To investigate the survival impact of common pharmaceuticals, which target stromal interactions, following a pancreaticoduodenectomy for pancreatic ductal adenocarcinoma. METHODS: Data was collected retrospectively for 164 patients who underwent a pancreaticoduodenectomy for pancreatic ductal adenocarcinoma(PDAC). Survival analysis was performed on patients receiving the following medications: angiotensin-converting enzyme inhibitors(ACEI)/angiotensin Ⅱ receptor blockers(ARB), calcium channel blockers(CCB), aspirin, and statins. Statistical analysis included Kaplan-meier survival estimates and cox multivariate regression; the latter of which allowed for any differences in a range of prognostic indicators between groups. Medications showing a significant survival benefit were investigated in combination with other medications to evaluate synergistic effects.RESULTS: No survival benefit was observed with respect to ACEI/ARB(n = 41), aspirin or statins on individual drug analysis(n = 39). However, the entire CCB group(n = 26) showed a significant survival benefit on multivariate cox regression; hazard ratio(HR) of 0.475(CI = 0.250-0.902, P = 0.023). Further analysis revealed that this was influenced by a group of patients who were taking aspirin in combination with CCB; median survival was significantly higher in the CCB + aspirin group(n = 15) compared with the group taking neither drug(n = 98); 1414 d vs 601 d(P = 0.029, logrank test). Multivariate cox regression revealed neither aspirin nor CCB had a statistically significant impact on survival when given alone, however in combination the survival benefit was significant; HR = 0.332(CI = 0.126-0.870, P = 0.025). None of the other medications showed a survival benefit in any combination.CONCLUSION: Aspirin + CCB in combination appears to increase survival in patients with PDAC, highlighting the potential clinical use of combination therapy to target stromal interactions in pancreatic cancer. | Samuel J Tingle John A Moir Steven A White | 2015 | World Journal of Gastrointestinal Pathophysiology2015，6，4： | 2 |
| 5 | Characterization of two new gene cassettes, aadA5 and dfrA17 显示文摘 | White P A Mclver C J Deng Y | 2000 | FEMS Microbiol Lett2000，182，2： | 2 |
| 6 | Analysis of a concentrated winding induction machine for adjustable speed drive applications-part Ⅱ:Motor design and performance 显示文摘 | Toliyat H A Lipo T A White J C | 1991 | IEEE Transactions on Energy Conversion1991，6，4： | 2 |
| 7 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 8 | Preparation, assay, and partial purification of a thymic lymphocytopoietic factor (thymosin)显示文摘 | GOLDSTEIN A L SLATER F D WHITE A | 1966 | Proc Natl Acad Sci USA1966，56，3： | 2 |
| 9 | A gene for hereditary pancreatitis maps to chromosome 7q35显示文摘 | DC Whitcomb RA Preston CE Aston MJ Sossenheimer PS Barua Y Zhang A Wong- Chong GJ White PG Wood LK Gates C Ulrich SP Martin JC Post GD Ehrlich | 1996 | Gastroenterology1996，，6： | 2 |
| 10 | Transbronchial needle aspiration guidance with CT fluoroscopy显示文摘 | White C S Weiner E A Patel P | 2000 | Chest2000，118，4： | 1 |
| 11 | In search of the Holy Grail-a further step in understanding metal hyperaccumulation? 显示文摘 | Baker A J M Whiting S N | 2002 | New Phytologist2002，155，： | 1 |
| 12 | Lithium (η3-aza-allyl) Type Complexes Derived from the Metallation of 2-(Me3 Si)3- n CHn C5 H4 N;Influence of Solvent and Degree of Substitution,n= 1 or 2,on the Nature of the Product显示文摘 | COLGAN D PAPASERGIO R RASTON C L WHITE A H | 1984 | ] Chern Soc Chem Comrnun1984，，： | 1 |
| 13 | Identification and Characterization of Coenzyme B12-Dependent Glycerol Dehydratase- and Diol Dehydratase- Encoding Genes from Metagenomic DNA Libraries Derived from Enrichment Cultures显示文摘 | Knietseh A Bowien S Whited G | 2003 | Appl Environ Microbiology2003，6，69： | 1 |
| 14 | Three-dimensional flexibility and stiffness properties of the human thoracic spine 显示文摘 | Panjabi M M Brand R A Jr White A A 3rd | | J Biomech0，1976，： | 1 |
| 15 | Soil deformation measurement using particle image velocimetry (PIV) and photogrammetry显示文摘 | WHITE D J TAKE W A BOLTON M D | 2003 | Geotechnique2003，53，7： | 1 |
| 16 | Identification and characterization of coenzyme B12-dependent glycerol dehydratase-and diol dehydratase-encoding genes from metagenomic DNA libraries derived from enrichment cultures显示文摘 | Knietsch A Bowien S Whited G | 2003 | Applied and Environmental Microbiology2003，69，： | 1 |
| 17 | Treatment of multiple sclerosis with daclizumab显示文摘 | Rose JW Watt HE White A | 2004 | Neurology2004，62，5： | 1 |
| 18 | Analysis of a concentrated winding induction machine for adjustable speed drive application part 2 (Motor design and performance) 显示文摘 | Toliyat H A Lipo T A White J C | 1991 | IEEE Transactions on Energy Conversion1991，6，4： | 1 |
| 19 | Genome sequence of the radio-resistant bacterium Deinococcus radiodurans R1 显示文摘 | White O Eisen J A Heidelberg J F | 1999 | Science1999，286，： | 1 |
| 20 | Full-wave simulation of electromagnetic coupling effects in RF and mixed-signal IC's using a time-domain finite-element method显示文摘 | WHITE D A STOWELL M | 2004 | IEEE Trans MTT2004，52，5： | 1 |
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