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| 1 | Abnormal activation of the synuclein-gamma gene in hepatocellular carcinomas by epigenetic alteration.显示文摘 | Zhao W Liu H Liu W Wu Y Chen W Jiang B Zhou Y Xue R Luo C Wang L Jiang JD Liu J | 2006 | 中国生物学文摘2006,20,4: | 31 |
| 2 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019,6,3: | 15 |
| 3 | 男性迟发性性腺功能减退症的检查、治疗和监测:国际男科学会(ISA)、国际老年男性研究会(ISSAM)、欧洲泌尿外科学会(EAU)、欧洲泌尿外科学院(EAA)和美国男科学会(ASA)联合推荐显示文摘简介
人口学资料明确显示:老年人口占总人口的百分率正逐年增加。当前,有关老年男性雄激素缺乏的问题逐渐成为令人感兴趣、但又充满争议的世界性话题。已经有横向和纵向的研究资料表明,随着年龄增大,成年男子的雄激素水平逐渐降低, | Wang C Nieschlage E Swerdloff R Behre HM Hellstrom WJ Gooren LJ Kaufman JM Legros JJ Lunenfeld B Morales A Morley JE Schulman C Thompson IM Weidner W Wu FCW 伍学焱(翻译) | 2011 | 国际生殖健康/计划生育杂志2011,30,1: | 8 |
| 4 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012,22,1: | 7 |
| 5 | A confidence limit for the empirical mode decomposition and Hilbert spectral analysis显示文摘 | Huang Norden E Wu Man-Li C Long Steven R Shen Samuel S.P Qu Wendong Gloersen Per Fan Kuang L | 2003 | Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences . 2003 (2037)2003,,2037: | 3 |
| 6 | A review of the Euplotidae (Hypotrichida, Ciliophora)显示文摘 | Curds C R Wu I C H | 1983 | Bull Br Mus Nat Hist1983,44,: | 3 |
| 7 | Generation of cDNA probes directed by amino acid sequence: Cloning of urate oxidase 显示文摘 | Lee C C Wu X Gibbs R A | 1988 | Science1988,239,: | 2 |
| 8 | A confidence limit for the empirical mode decomposition and Hilbert spectral analysis显示文摘 | Huang Norden E Wu Man-Li C Long Steven R Shen Samuel S.P Qu Wendong Gloersen Per Fan Kuang L | 2003 | Proceedings of the Royal Society A: Mathematical Physical and Engineering Sciences2003,,2037: | 2 |
| 9 | An image-guided mobile robotic welding system for SMAW repair processes 显示文摘 | Tung P C Wu M C Hwang Y R | 2004 | Internaotional Journal of Machine Tools & Manufacture2004,44,: | 1 |
| 10 | A novel power factor control scheme for high-power GTO current-source converter显示文摘 | Xiao Yuan Wu Bin Steven C R | 1998 | IEEE Transactions on Industry Applications1998,34,6: | 1 |
| 11 | Coefficient of restitution and rotational motions of rockfall impacts显示文摘 | CHAU K T WONG R H C WU J J | 2002 | International Journal of Rock Mechanics & Mining Sciences2002,39,: | 1 |
| 12 | Developmental expression of key steroidogenie enzymes in the brain of protandrous black porgy fisb, Acanthopagrus sehlegeli 显示文摘 | Tomy S Wu G C Huang H R | 2007 | Neuroendoerinol2007,9,8: | 1 |
| 13 | Maneuvering target tracking with colored noise 显示文摘 | Wu W R Chang D C | 1996 | IEEE Transactions on Aerospace and Electronic Systems (S0018-9251)1996,32,4: | 1 |
| 14 | A confidence limit for theempirical mode decomposition and the Hilbert spectralanalysis显示文摘 | Huang N E Wu M C Long S R | 2003 | Proceedings of the Royal Society London:Series A2003,31,: | 1 |
| 15 | Description of distributed features of the nestin - containing cells in brains of adult mice: a potential source of neural precursor cells 显示文摘 | Xu R Wu C Tao Y | 2010 | J Neurosci Res2010,88,5: | 1 |
| 16 | Novel baculovirus DNA elements strongly stimulate activities of exogenous and endogenous promoters 显示文摘 | LO H R CHOU C C WU T Y | 2002 | The Journal of Biological Chemistry2002,277,7: | 1 |
| 17 | (-)-Ledol from the liverwort Cephaloziella recurvifolia and the clarification of its identity显示文摘 | WU C L HUANG Y M CHEN J R | 1996 | Phytochemistry1996,42,: | 1 |
| 18 | On a joint distribution for the risk process with constant interest force显示文摘 | Wu R Wang G J Zhang C S | 2005 | Insurance:Mathematics and Economics2005,36,: | 1 |
| 19 | An improved formalism for FDTD analysis of thin-slot problems by conformal mapping technique显示文摘 | Wu C T Pang Y H Wu R B | 2003 | IEEE Trans Antennas Propagation2003,51,9: | 1 |
| 20 | Studies on the synthesis and antibacterial activities of polymeric quaternary ammonium salts from dimethylaminoethyl methacry- late 显示文摘 | Lu G Q Wu D C Fu R W | 2007 | React Funet Polym2007,67,4: | 1 |