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| 1 | 节段性小肠移植手术中采用自体髂内血管进行血管重建显示文摘背景:本研究旨在评估自体髂内动静脉可否用于异体及自体节段性小肠移植手术的血管重建。方法:2011年1月至2019年1月间34例小肠移植患者纳入研究,其中19例为亲属活体移植,15例为自体移植。收集患者临床资料、血管重建类型及术后并发症进行分析。结果:全组男性20例,女性14例,中位年龄35岁。在34例小肠移植中,22例(64.7%,其中异体移植和自体移植各11例)采用自体髂内动脉脉进行血管重建,12例(35.3%)直接行血管吻合。血管重建耗时(21˘6)min。与直接吻合组相比,血管重建组患者手术总时长(530˘226 vs 440˘116 min,P=0.208)和冷缺血时间(159˘49 vs 125˘66 min,P=0.097)均有延长的趋势,但差异并未达到统计学意义。直接吻合组术后血栓形成发生率较血管重建组有增高的趋势(16.7%vs 0%,P=0.118)。中位随访36.9个月,无一例出现静脉狭窄或假性动脉瘤。19例异体移植患者中,4例(21.1%)发生急性排斥反应,1例(5.2%)出现慢性排斥反应。结论:本组数据显示,采用自体髂内动静脉进行血管重建可有力促进小肠移植的开展,同时有望降低术后血管并发症的风险。 | Guosheng Wu Yinglun Wu Mian Wang Wentong Zhang Chaoxu Liu Tingbo Liang | 2021 | Gastroenterology Report2021，9，4： | 2 |
| 2 | Immortalized mouse dental papilla mesenchymal cells preserve odontoblastic phenotype and respond to bone morphogenetic protein 2显示文摘 | Feng Wang Li-An Wu Wentong Li Yuan Yang Feng Guo Qingping Gao Hui-Hsiu Chuang Lisa Shoff Wei Wang Shuo Chen | 2013 | In Vitro Cellular & Developmental Biology - Animal2013，，： | 1 |
| 3 | Spatiotemporal variability of rain-on-snow events in the arid region of Northwest China显示文摘Rain-on-snow(ROS)events involve rainfall on snow surfaces,and the occurrence of ROS events can exacerbate water scarcity and ecosystem vulnerability in the arid region of Northwest China(ARNC).In this study,using daily snow depth data and daily meteorological data from 68 meteorological stations provided by the China Meteorological Administration National Meteorological Information Centre,we investigated the spatiotemporal variability of ROS events in the ARNC from 1978 to 2015 and examined the factors affecting these events and possible changes of future ROS events in the ARNC.The results showed that ROS events in the ARNC mainly occurred from October to May of the following year and were largely distributed in the Qilian Mountains,Tianshan Mountains,Ili River Valley,Tacheng Prefecture,and Altay Prefecture,with the Ili River Valley,Tacheng City,and Altay Mountains exhibiting the most occurrences.Based on the intensity of ROS events,the areas with the highest risk of flooding resulting from ROS events in the ARNC were the Tianshan Mountains,Ili River Valley,Tacheng City,and Altay Mountains.The number and intensity of ROS events in the ARNC largely increased from 1978 to 2015,mainly influenced by air temperature and the number of rainfall days.However,due to the snowpack abundance in areas experiencing frequent ROS events in the ARNC,snowpack changes exerted slight impact on ROS events,which is a temporary phenomenon.Furthermore,elevation imposed lesser impact on ROS events in the ARNC than other factors.In the ARNC,the start time of rainfall and the end time of snowpack gradually advanced from the spring of the current year to the winter of the previous year,while the end time of rainfall and the start time of snowpack gradually delayed from autumn to winter.This may lead to more ROS events in winter in the future.These results could provide a sound basis for managing water resources and mitigating related disasters caused by ROS events in the ARNC. | YANG Zhiwei CHEN Rensheng LIU Zhangwen ZHAO Yanni LIU Yiwen WU Wentong | 2024 | Journal of Arid Land2024，16，4： | 0 |
| 4 | Mid1ip1b modulates apical reorientation of non-centrosomal microtubule organizing center in epithelial cells显示文摘In most kinds of animal cells,the centrosome serves as the main microtubule organizing center(MTOC)that nucleates microtubule arrays throughout the cytoplasm to maintain cell structure,cell division and intracellular transport.Whereas in epithelial cells,non-centrosomal MTOCs are established in the apical domain for generating asymmetric microtubule fibers and cilia in epithelial cells for the organ morphogenesis during embryonic development.However,the mechanism by which MTOCs localize to the apical domain in epithelial cells remains largely unknown.Here,we show that Mid1ip1b has a close interaction with g-tubulin protein,the central component of MTOC,and modulates lumen opening of the neural tube,gut,intestine,and kidney of zebrafish.Knockdown or dominant negative effect of Mid1ip1b resulted in failure of lumen formation of the organs as aforementioned.Moreover,the non-centrosomal MTOCs were unable to orientate to the apical domain in Mid1ip1b knockdown epithelial cells,and the centrosomal MTOCs were inaccurately placed in the apical domain,resulting in defective formation of asymmetric microtubules and misplacement of cilia in the apical domain.These data uncover a molecule that controls the proper localization of MTOCs in the apical domain in epithelial cells for organ morphogenesis during embryonic development. | Xin Zhou Chun Xiao Yu Li Yanna Shang Dongqin Yin Siying Li Bo Xiang Ran Lu Yi Ji Yang Wu Wentong Meng Hongyan Zhu Jin Liu Huozhen Hu Xianming Mo Hong Xu | 2018 | Journal of Genetics and Genomics2018，45，8： | 0 |
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