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| 1 | Comparison of perceived pain and patients’ satisfaction with traditional local anesthesia and single tooth anesthesia: A randomized clinical trial显示文摘BACKGROUND Contemporary innovations in the area of local anesthesia have attempted to provide an absolutely pain free experience for patients.Since the introduction of Computer-Controlled Local Anesthetic Delivery Systems to dentistry,many studies have compared its efficacy and safety to conventional anesthesia.However,very few studies have compared single tooth anesthesia(STA)and traditional local anesthesia.AIM To compare pain rating,changes in blood pressure,and heart rate during the local anesthetic injection.The secondary objectives were to measure the patients’level of satisfaction and the differences in anesthetic efficiency between the STA system and traditional local infiltration.METHODS A randomized controlled trial was conducted and a total of 80 patients with dental restorative needs were enrolled for the study.The patients were evaluated for their general physical status and oral clinical findings before enrollment.Information regarding perceived pain,changes in heart rate and blood pressure,and patients’satisfaction was collected using an electronic data form and was analyzed using paired and unpaired t-tests.RESULTS No significant difference was noted in perceived pain(P=0.59)and systolic blood pressure(P=0.09)during anesthetic injection using both traditional and STA techniques.STA patients had a significantly higher heart rate during anesthesia,although a statistically significant difference was noted among the traditional anesthesia and the STA groups even before anesthesia.During the restorative procedure,less pain was perceived by STA patients on the Wong-Baker FACES pain scale,which was statistically significant(P<0.001).Analyses of post-procedure patient responses showed that STA patients had a significantly better treatment experience and preferred to have the same method of injection in the future(P=0.04).CONCLUSION STA system can provide less painful and more comfortable restorative treatment procedures in comparison to the traditional infiltration technique. | Mohammad I Al-Obaida Mehdiya Haider Rawan Hashim Wafa AlGheriri Sree Lalita Celur Samar A Al-Saleh Ebtissam M Al-Madi | 2019 | World Journal of Clinical Cases2019，7，19： | 8 |
| 2 | Profiling cellular bioenergetics, glutathione levels, and caspase activities in stomach biopsies of patients with upper gastrointestinal symptoms显示文摘AIM: To measure biochemical parameters in stomach biopsies and test their suitability as diagnostic biomarkers for gastritis and precancerous lesions.METHODS: Biopsies were obtained from the stomachs of two groups of patients(n = 40) undergoing fiberoptic endoscopy due to upper gastrointestinal symptoms. In the first group(n = 17), only the corpus region was examined. Biopsies were processed for microscopic examination and measurement of mitochondrial O2 consumption(cellular respiration), cellular adenosine triphosphate(ATP), glutathione(GSH), and caspase activity. In the second group of patients(n = 23), both corpus and antral regions were studied. Some biopsies were processed for microscopic examination, while the others were used for measurements of cellular respiration and GSH level.RESULTS: Microscopic examinations of gastric corpus biopsies from 17 patients revealed normal mucosae in 8 patients, superficial gastritis in 7 patients, and chronic atrophic gastritis in 1 patient. In patients with normal histology, the rate(mean ± SD) of cellular respiration was 0.17 ± 0.02 μmol/L O2 min-1 mg-1, ATP content was 487 ± 493 pmol/mg, and GSH was 469 ± 98 pmol/mg. Caspase activity was detected in 3 out of 8 specimens. The values of ATP and caspase activity were highly variable. The presence of superficial gastritis had insignificant effects on the measured biomarkers. In the patient with atrophic gastritis, cellular respiration was high andATP was relatively low, suggesting uncoupling oxidative phosphorylation. In the second cohort of patients, the examined biopsies showed either normal or superficial gastritis. The rate of cellular respiration(O2. μmol/L min-1 mg-1) was slightly higher in the corpus than the antrum(0.18 ± 0.05 vs 0.15 ± 0.04, P = 0.019). The value of GSH was about the same in both tissues(310 ± 135 vs 322 ± 155, P = 0.692).CONCLUSION: The corpus mucosa was metabolically more active than the antrum tissue. The data in this study will help in understanding the pathophysiology of gastric mucosa. | Ali S Alfazari Bayan Al-Dabbagh Wafa Al-Dhaheri Mazen S Taha Ahmad A Chebli Eva M Fontagnier Zaher Koutoubi Jose Kochiyi Sherif M Karam Abdul-Kader Souid | 2015 | World Journal of Gastroenterology2015，21，2： | 2 |
| 3 | Shear behavior of high-strength fiber reinforced concrete beams 显示文摘 | ASHOUR S A HASANAIN G S WAFA F F | 1992 | ACI Struct J1992，89，2： | 1 |
| 4 | Prevention of transfusion-associated graft-versus-host disease by photochemical treatment显示文摘 | Wafa T Reames A | 1999 | Blood1999，93，： | 1 |
| 5 | Prospective study of seroconversion for hepatitis C virus antibodies in hemodialysis patients:One center experience显示文摘 | Mohamed AO Bernieh B Wafa A | 1996 | Saudi J Kidney Dis Transplant Bull1996，6，： | 1 |
| 6 | 2 in combination with partial monosomy 9pter in a Syrian girl 显示文摘 | A1 Achkar W Wafa A Moassass F et aL Partial trisomy 9p22 to 9p24 | 2010 | Mol Cytogenet2010，3，： | 1 |
| 7 | Prevention of transfusion-associated graft-versus-host disease by photochemical treatment显示文摘 | Grass JA Wafa T Reames A | 1999 | Blood1999，93，9： | 1 |
| 8 | High-speed RF multi-modulus prescaler architecture for Σ-Δ fractional-N PLL frequency synthesizers显示文摘 | Wafa A Ahmed A | 2004 | IEEE J Sol Sta Circ2004，4，23： | 1 |
| 9 | Modelling growth and food intake rhythms of brook trout Salvelinus fontinalis under the effects of density and ration显示文摘 | Wafa A H Pierre D Daniel B | 2004 | Ecological Modelling2004，175，4： | 1 |
| 10 | Mechanical properties of high-strength fiber reinforced concrete显示文摘 | WAFA F F ASHOUR S A | 1992 | ACI Materials Journal1992，89，5： | 1 |
| 11 | Prevention of transfusion-associated draft-versus-host disease by photochemical treatment显示文摘 | Grass JA Wafa T Reames A | 1999 | Blood1999，93，9： | 1 |
| 12 | Flexural behavior of high-strength fiber reinforced concrete beams 显示文摘 | ASHOUR S A WAFA F F | 1993 | ACI Struct J1993，90，3： | 1 |
| 13 | Shear behavior of high-strength fiber reinforced concrete beams 显示文摘 | ASHOUR S A HASANAIN G S WAFA F F | 1992 | ACI Struct J1992，89，2： | 1 |
| 14 | Shear behavior of high-strength fiber reinforced concrete beams显示文摘 | ASHOUR S A HASANAIN G S WAFA F F | 1992 | ACI Structural Journal1992，86，2： | 1 |
| 15 | Shear behaviour of high-strength fiber- reinforced concrete beams显示文摘 | Ashour S A Hasanain G S Wafa F F | 1992 | ACI Structural Journal1992，89，2： | 1 |
| 16 | A conceptual framework for effective implementation of JIT:an empirical investigation显示文摘 | Marwan A Wafa Mahound M Yasin | 1998 | International Journal of Operations & Production Management1998，18，11： | 1 |
| 17 | Prospective study of serocoversion for hepatitis C antibodies in hemodialysis patients:one center experience显示文摘 | Mohamed AO Bernieh B Wafa A | 1996 | Saudi J Kidney Transplant Bull1996，7，： | 1 |
| 18 | Cytogenetic abnormalities and Y-chromosome microdeletions in infertile Syrian males显示文摘 | A1-Achkar W Wafa A Moassass F | 2013 | Biomed Rep2013，1，2： | 1 |
| 19 | Sleep disorders in hemodialysis patients显示文摘 | Sabry A A Abo-Zenah H Wafa E | 2010 | Saudi journal of kidney diseases and transplantation2010，21，2： | 1 |
| 20 | Flexural behavior of high-strength fiber reinforced concrete beams 显示文摘 | Ashour samir A Wafa Faisal F | 1992 | ACI Structural Jour-nal1992，89，2： | 1 |
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