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| 1 | Ovarian cancer stem cells: Can targeted therapy lead to improved progression-free survival?显示文摘Despite significant effort and research funds, epithelial ovarian cancer remains a very deadly disease. There are no effective screening methods that discover early stage disease; the majority of patients are diagnosed with advanced disease. Treatment modalities consist primarily of radical debulking surgery followed by taxane and platinum-based chemotherapy. Newer therapies including limited targeted agents and intraperitoneal delivery of chemotherapeutic drugs have improved disease-free intervals, but failed to yield longlasting cures in most patients. Chemotherapeutic resistance, particularly in the recurrent setting, plagues the disease. Targeting the pathways and mechanisms behind the development of chemoresistance in ovarian cancer could lead to significant improvement in patient outcomes. In many malignancies, including blood and other solid tumors, there is a subgroup of tumor cells, separate from the bulk population, called cancer stem cells(CSCs). These CSCs are thought to be the cause of metastasis, recurrence and resistance. However, todate, ovarian CSCs have been difficult to identify, isolate, and target. It is felt by many investigators that finding a putative ovarian CSC and a chemotherapeutic agent to target it could be the key to a cure for this deadly disease. This review will focus on recent advances in this arena and discuss some of the controversies surrounding the concept. | Christen L Walters Haygood Rebecca C Arend J Michael Straughn Donald J Buchsbaum | 2014 | World Journal of Stem Cells2014，6，4： | 7 |
| 2 | Naming and outline of Dothideomycetes-2014 including proposals for the protection or suppression of generic names显示文摘Article 59.1,of the International Code of Nomenclature for Algae,Fungi,and Plants(ICN;Melbourne Code),which addresses the nomenclature of pleomorphic fungi,became effective from 30 July 2011.Since that date,each fungal species can have one nomenclaturally correct name in a particular classification.All other previously used names for this species will be considered as synonyms.The older generic epithet takes priority over the younger name.Any widely used younger names proposed for use,must comply with Art.57.2 and their usage should be approved by the Nomenclature Committee for Fungi(NCF).In this paper,we list all genera currently accepted by us in Dothideomycetes(belonging to 23 orders and 110 families),including pleomorphic and nonpleomorphic genera.In the case of pleomorphic genera,we follow the rulings of the current ICN and propose single generic names for future usage.The taxonomic placements of 1261 genera are listed as an outline.Protected names and suppressed names for 34 pleomorphic genera are listed separately.Notes and justifications are provided for possible proposed names after the list of genera.Notes are also provided on recent advances in our understanding of asexual and sexual morph linkages in Dothideomycetes.A phylogenetic tree based on four gene analyses supported 23 orders and 75 families,while 35 families still lack molecular data. | Nalin N.Wijayawardene Pedro W.Crous Paul M.Kirk David L.Hawksworth Saranyaphat Boonmee Uwe Braun Dong-Qin Dai Melvina J.D’souza Paul Diederich Asha Dissanayake Mingkhuan Doilom Singang Hongsanan E.B.Gareth Jones Johannes Z.Groenewald Ruvishika Jayawardena James D.Lawrey Jian-Kui Liu Robert Lücking Hugo Madrid Dimuthu S.Manamgoda Lucia Muggia Matthew P.Nelsen Rungtiwa Phookamsak Satinee Suetrong Kazuaki Tanaka Kasun M.Thambugala Dhanushka N.Wanasinghe Saowanee Wikee Ying Zhang Andre Aptroot H.A.Ariyawansa Ali H.Bahkali D.Jayarama Bhat Cécile Gueidan Putarak Chomnunti G.Sybren De Hoog Kerry Knudsen Wen-Jing Li Eric H.C.McKenzie Andrew N.Miller Alan J.L.Phillips Marcin Piatek Huzefa A.Raja Roger S.Shivas Bernad Slippers Joanne E.Taylor Qing Tian Yong Wang Joyce H.C.Woudenberg Lei Cai Walter M.Jaklitsch Kevin D.Hyde | 2014 | Fungal Diversity2014，，6： | 2 |
| 3 | Dietary glycemic load and atherothrombotic risk显示文摘 | Simin L Walter C | 2002 | Current Atherosclerosis Reports2002，4，： | 1 |
| 4 | Distribution of some volatile nitrosamines in cooked bacon显示文摘 | GOUGH T A GOOGHEAD K WALTERS C L | 1976 | Journal of the Science of Food and Agriculture1976，27，2： | 1 |
| 5 | Identification of mi- crobial and thermogenic gas components from Upper Devonian black shale cores,Illinois and Michigan basins显示文摘 | Martini A M Walter L M Mclntosh J C | 2008 | AAFG Bul- letin2008，92，3： | 1 |
| 6 | Longevity of seeds in a genebank: species characteristics 显示文摘 | Walters C Wheeler L M Grotenhuis J M | 2005 | Seeds Sci Res2005，15，： | 1 |
| 7 | Metallic fast reactor fuels显示文摘 | HOFMAN G L WALTERS L C BAUER T H | 1997 | Progress in Nuclear Energy1997，31，12： | 1 |
| 8 | Extensive microbial modificationof formation water geochemistry:Case study from a Midcontinentsedimentary basin,United States显示文摘 | McIntosh J C Walter L M Martini A M | 2004 | Geological Society of America Bulletin2004，116，56： | 1 |
| 9 | Higher rates of autism and attention deficit/hyperactivity disorder in American children:Are food quality issues impacting epigenetic inheritance?显示文摘In the United States,schools offer special education services to children who are diagnosed with a learning or neurodevelopmental disorder and have difficulty meeting their learning goals.Pediatricians may play a key role in helping children access special education services.The number of children ages 6-21 in the United States receiving special education services increased 10.4%from 2006 to 2021.Children receiving special education services under the autism category increased 242%during the same period.The demand for special education services for children under the developmental delay and other health impaired categories increased by 184%and 83%respectively.Although student enrollment in American schools has remained stable since 2006,the percentage distribution of children receiving special education services nearly tripled for the autism category and quadrupled for the developmental delay category by 2021.Allowable heavy metal residues remain persistent in the American food supply due to food ingredient manufacturing processes.Numerous clinical trial data indicate heavy metal exposures and poor diet are the primary epigenetic factors responsible for the autism and attention deficit hyperactivity disorder epidemics.Dietary heavy metal exposures,especially inorganic mercury and lead may impact gene behavior across generations.In 2021,the United States Congress found heavy metal residues problematic in the American food supply but took no legislative action.Mandatory health warning labels on select foods may be the only way to reduce dietary heavy metal exposures and improve child learning across generations. | Renee J Dufault Raquel A Crider Richard C Deth Roseanne Schnoll Steven G Gilbert Walter J Lukiw Amanda L Hitt | 2023 | World Journal of Clinical Pediatrics2023，12，2： | 1 |
| 10 | Microbial pro-duction and modification of gases in sedimentary basins:A geochemical case study from a Devonian shale gas play,Michigan basin显示文摘 | Martini A M Walter L M Ku T C W | 2003 | AAPG Bulletin2003，87，8： | 1 |
| 11 | The effect of igneous intrusive bodies on sedimentary thermal maturity 显示文摘 | Wang X Leche L Walters C | 1989 | Organic Geochemistry1989，64，6： | 1 |
| 12 | Rice and resistant starch:different content depending on chosen methodogy显示文摘 | SILVA L P da WALTER M DENARDIN C C | 2005 | Journal of Food Composition Analysis2005，18，： | 1 |
| 13 | An effect of impurity atoms on the energy relationship of(100)and(110)surfaces in high purity silicon steel显示文摘 | WALTER J L DUNN C G | 1960 | Acta Metallurgica1960，8，8： | 1 |
| 14 | The identification of 2,4-diacetylphloroglucinol as an antifungal metabolite produced by cutaneous bacteria of the salamander Plethodon cinereus显示文摘 | Brucker R M Baylor C M Walters R L | 2008 | Journal of Chemical Ecology2008，34，1： | 1 |
| 15 | The Mechanism of Crease Resistance Development on Cellulosic Fabrics Treated with Dimethylol Ethylene Urea显示文摘 | Walter H C Buxbaum J K Green L Q | 1957 | Textile Research Journal1957，27，2： | 1 |
| 16 | Application of Box-Behnken design in the optimisation of an on-line pre-concentration system using knotted reactor for cadmium determination by flame atomic absorption spectrometry显示文摘 | Anderson S Souza Walter N L dos Santos Sérgio L C Ferreira | | 0，，： | 1 |
| 17 | Growth of(110)-oriented grains in high-purity silicon iron:a unique form of secondary recrystallization显示文摘 | WALTER J L DUNN C G | 1960 | Trans AIME1960，218，： | 1 |
| 18 | Thirty years of fuels and materials information from EBR-Ⅱ显示文摘 | WALTERS L C | 1999 | Journal of Nuclear Materials1999，270，： | 1 |
| 19 | Tertiary recrystallization in silicon iron显示文摘 | WALTER J L DUNN C G | 1959 | Trans AIME1959，215，： | 1 |
| 20 | Identification of microbial and thermogenic gas components from Upper Devonian black shale cores, Illinois and Michigan basins 显示文摘 | Martini A M Walter L M Mclntosh J C | 2008 | AAPG Bulletin2008，92，3： | 1 |
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