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| 1 | High doses of α-galactosylceramide potentiate experimental autoimmune encephalomyelitis by directly enhancing Th17 response显示文摘伪 - Galactosylceramide (伪 - GC ) 广泛地被知道激活不变的自然漂亮 T (iNKT ) 压制髓磷脂的房间抗原特定的 Th1 回答,保护易受影响的老鼠免于试验性的自体免疫的脑脊髓炎(EAE ) 。这里,我们表明那高加重,而非改善的伪 - GC 开 EAE 的意外发现。当与高剂量的伪 - GC 对待的 MOG35-55-specific T 房间被变成 na 时,类似的结果被观察 ? ve syngeneic 接受者老鼠。进一步的学习证明伪 - GC 的高剂量直接通过 STAT3 的 phosphorylation 和 NF-魏 B 的激活由 CD4+CD44+ 记忆 T 房间的激活提高 Th17 和 Th1 反应。不同于由伪 - GC 的低剂量的 iNKT 房间的激活,伪 - GC 的高剂量直接交往了, CD1d 在 T 房间上表示了并且激活 Th17 和 Th1 房间。而且,介绍抗原的房间(APC ) 主要表示 CD1d1,而 CD4+ T 房间快车 CD1d2 的多数。由 RNAi 的 CD1d1 或 CD1d2 基因表示击倒分别地防碍 iNKT 或 Th17/Th1 房间的激活。因此,伪 - GC 处理能改善或变得更坏由雇佣取决于剂量的 APC 或 Th17/Th1 房间的 EAE 使用了。 | Gaochao Qian Xia Qin Ying Qin Zang Baoxue Ge Taylor B Guo Bing Wan Lei Fang Jingwu Z Zhang | 2010 | Cell Research2010，20，4： | 3 |
| 2 | Measurement of the runaway electrons in the HT -7 tokamak显示文摘 | CHEN Z Y WAN B N LIN S Y | 2006 | REVIEW OF SCIENTIFIC INSTRUMENTS 772006，，： | 1 |
| 3 | Induction of vascular endothelial phenotype and cellular proliferation from human cord blood stem cells cultured in simulated microgravity 显示文摘 | Chiu B Wan J Z Abley D | 2005 | Acta Astronaut2005，56，912： | 1 |
| 4 | Investigation of catalytic glycolysis of PET by differential scanning calorimetry显示文摘 | KAO C Y CHENG W H WAN B Z | 2000 | Thermochimica Acta2000，292，12： | 1 |
| 5 | Response of soil CO2 efflux to water manipulation in a tall grass prairie ecosystem显示文摘 | Liu X Z Wan S Q Su B | | 0，，02： | 1 |
| 6 | ICRF siliconization in HT-7 superconducting Tokamak显示文摘 | Gong X Z Li J G Wan B N | 2001 | J Nuclear Mater2001，，： | 1 |
| 7 | Response of soil CO2 efflux to water manipulation in a tallgrass prairie ecosystem 显示文摘 | LIU X Z WAN S Q SU B | 2002 | Plant and Soil2002，240，： | 1 |
| 8 | Structural response reconstruction based on the modal snperposition method in the presence of closely spaced modes 显示文摘 | WAN Z M LI S D HUANG Q B | 2014 | Mechanical Sys- tems and Signal Processing2014，42，12： | 1 |
| 9 | Tin-based oxide anode for lithium-ion batteries with low irreversible capacity显示文摘 | Wan K B Li S F Y Gao Z Q | 1998 | J Power Sources1998，75，1： | 1 |
| 10 | Dynamics of Runaway Electrons in the Lower Hybrid Current Drive Plasmas in the HT - 7 tokamak显示文摘 | Chen Z Y Wan B N Lin S Y | 2006 | Plasma Physics and controlled Fusion2006，，10： | 1 |
| 11 | Highly efficient and practical phospboramidite-copper catalysts for amination of aryl iodides and heteroaryl bromides with alkylamines and N (H)-heterocycles显示文摘 | ZHANG Z MAO J WAN B | 2006 | Tetrahedron2006，62，： | 1 |
| 12 | Enhancement of Runaway Production in Lower Hybrid Current Driven Plasma with IBW Heating in the HT- 7 Tokamak显示文摘 | Chen Z Y Wan B N Ling B L | 2008 | Plasma physics and controlled fusion2008，，50： | 1 |
| 13 | Technical note: development of Hemipyrellia ligurriens ( Wiedemarm ) ( Diptera: Calliphoridae ) at constant temperatures: applications in estimating postmortem interval显示文摘 | Yang Y Q Lyu Z Li X B Li K Yao L Wan L H | 2015 | Forensic Sci Int2015，253，： | 1 |
| 14 | Imaging and navigation meas- urement of acetabular component position in THA 显示文摘 | Wan Z Malik A Jaramaz B | 2009 | Clin Orthop Relat Res2009，467，1： | 1 |
| 15 | Graphene derivatives: Synthesis and applications显示文摘 | Wan W B Zhao Z B Fan Y R | 2011 | Progress in Chemistl%2011，23，9： | 1 |
| 16 | Stable isotopic evidence for climate and basin evolu- tion of the Late Cretaceous Songliao basin, China 显示文摘 | Chamberlain C P Wan X Q Graham S A Carroll A R Doeb- bert A C Sageman B B Blisniuk P Kent-Corson M L Wang Z Wang C S | 2013 | Palaeo- geogr Palaeoclimatol Palaeoecol2013，385，： | 1 |
| 17 | Response of soil CO2 efflux to water manipulation in a tall grass prairie ecosystem显示文摘 | Liu X Z Wan S Q Su B | 2002 | Plant and Soil2002，240，： | 1 |
| 18 | A validation model for measurement of acetabular component position显示文摘 | Malik A Wan Z Jaramaz B | 2010 | J Arthroplasty2010，25，5： | 1 |
| 19 | A novel concept of convective heat transfer enhancement 显示文摘 | GUO Z Y LI D Y WAN( B X | 1998 | International Journal of Heat and Mass Transfer1998，41，14： | 1 |
| 20 | Suzuki -miyaura coupling reaction by Pd( Ⅱ ) -catalyzed aromatic C--H bond activation di- rected by an N- alkyl acetamino group 显示文摘 | SHI Z J LIB J WAN X B | 2007 | Angew Chem Int Ed2007，46，29： | 1 |
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