5篇
您的检索式：作者名="Warren Tate"
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| 1 | Role of mitochondria, oxidative stress and the response to antioxidants in myalgic encephalomyelitis/chronic fatigue syndrome: A possible approach to SARS-CoV-2 ’long-haulers’?显示文摘A significant number of SARS-CoV-2 (COVID-19) pandemic patients have developed chronic symptoms lasting weeks or months which are very similar to those described for myalgic encephalomyelitis/chronic fatigue syndrome. This study reviews the current literature and understanding of the role that mitochondria, oxidative stress and antioxidants may play in the understanding of the pathophysiology and treatment of chronic fatigue. It describes what is known about the dysfunctional pathways which can develop in mitochondria and their relationship to chronic fatigue. It also reviews what is known about oxidative stress and how this can be related to the pathophysiology of fatigue, as well as examining the potential for specific therapy directed at mitochondria for the treatment of chronic fatigue in the form of antioxidants. This study identifies areas which require urgent, further research in order to fully elucidate the clinical and therapeutic potential of these approaches. | Emily Wood Katherine H.Hall Warren Tate | 2021 | Chronic Diseases and Translational Medicine2021，7，1： | 4 |
| 2 | The type 2 anti-Müllerian hormone receptor has splice variants that are dominant-negative inhibitors显示文摘 | Floriane M. Imhoff Dee Yang Suneeth F. Mathew Andrew N. Clarkson Yui Kawagishi Warren P. Tate Kyoko Koishi Ian S. McLennan | 2013 | FEBS Letters2013，，12： | 1 |
| 3 | Secreted amyloid precursor proteins promote proliferation and glial differentiation of adult hippocampal neural progenitor cells显示文摘 | Sara Baratchi Jane Evans Warren P Tate | 2012 | Hippocampus2012，22，7： | 1 |
| 4 | Roles of amyioid precursor protein and its fragmerits inregulating neural activity,plasticity and memory显示文摘 | Paul R Turner Kate O Connor Warren P Tate | 2003 | Prog Neurobiol2003，70，1： | 1 |
| 5 | Accommodating the bacterial decoding release factor as an alien protein among the RNAs at the active site of the ribosome显示文摘蛋白质合成由的译码的版本因素(RF ) 扳机结束机能上地模仿国王跨越译码的中心和核糖体的 peptidyl 移转酶中心(PTC ) 的 tRNA。在结构上,它必须适合进为 tRNA 精心制作并且由五另外的 RNA 包围了的一个地点,也就是带完成的多肽,信使 rna 和三 rRNAs 的邻近的 peptidyl tRNA。这被从导致允许它联系 PTC 的一个批评 conformational 变化的蛋白质的身体扩大一个结构的领域完成。有提供的 RF 的细菌的结束建筑群的一个结构的模型证明它与站鳕鱼的第一,第二和第三个库做靠近的接触在上在有二个分开的环的信使 rna 组织:在螺旋 alpha5 的尖端的反密码子环和环。反密码子环也联系基础追随者那上的站鳕鱼被知道强烈影响结束效率。它与 PTC 的关键 RNA 结构证实领域 3 蛋白质的靠近的接触。为结束的信使 rna 信号包括站在上游以及下游的序列哄骗在上,并且这可以一起反映结构的限制让 tRNA 和 RF 的特定的联合固定到核糖体上。一条不偏的 SELEX 途径作为一个工具被调查了在核糖体的活跃中心以内在它的不同有约束力的符合构造识别细菌的 RF 的潜在的 rRNA 有约束力的接触。 | Elizabeth S Poole David J Young Marjan E Askarian-Amiri Debbie-Jane G Scarlett Warren P Tate | 2007 | Cell Research2007，17，7： | 0 |
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