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| 1 | Inhibition of lung cancer cell proliferation mediated by human mesenchymal stem cells显示文摘人的间充质的干细胞(hMSCs ) 主要为他们的潜在的临床的使用被学习。最近,癌症研究的领域里的许多注意对 hMSCs 被给予了。在这研究,我们由使用一个合作文化系统和调节 hMSCs 的媒介在 vitro 并且在 vivo 在肺癌症房间线 SK-MES-1 和 A549 的增长上调查了 hMSCs 的影响。我们的结果证明 hMSCs 能禁止 SK-MES-1 和 A549 房间的增长,并且经由一些可溶的因素在 vitro 导致肿瘤房间的 apoptosis。动物学习证明从 hMSCs 的这些可溶的因素能由 preliminarily 与调节 hMSCs 的媒介对待肿瘤细胞压制 tumorigenesis 和肿瘤 angiogenesis。在肿瘤房间的脉管的 endothelial 生长因素的 downregulated 表示可能是在肿瘤 angiogenesis 的干扰的机制,它被西方的污点分析和 immunohistochemistry 试金验证。一起拿,我们的结果建议 hMSCs 能由 secreting 一些禁止肿瘤细胞生长可溶的因素。 | Lin Li Hui Tian Zhitao Chen Weiming Yue Shuhai Li Wenjun Li | 2011 | Acta Biochimica et Biophysica Sinica2011，43，2： | 11 |
| 2 | A novel subsidence monitoring technique based on space-surface bistatic differential interferometry using GNSS as transmitters显示文摘Synthetic Aperture Radar Differential Interferometry(DIn SAR) technique is an effective tool with large coverage and high spatial accuracy for subsidence monitoring. Nevertheless, the temporal resolution is usually poor so that rapid deformation cannot be measured due to the long revisit time of radar satellites.Bistatic SAR Differential Interferometry technique using Global Navigation Satellite System(GNSS) as illuminator has a shorter revisit time, whereas the measurement accuracy is constrained by low signal power, narrow bandwidth and atmospheric delay error. To cope with these problems, in this paper, we propose a novel subsidence monitoring technique based on Space-Surface bistatic Differential Interferometry(SS-DI) with GNSS transmitters, where two stations consist of a reference one and a measurement one that are deployed on the ground. First, we applied a space differential processing between two stations to cancel identical errors such as tropospheric and ionospheric errors etc. Then we used a long time coherent integration to improve the signal noise ratio. Subsequently, we also utilized a time differential processing to construct double differential equations with respect to unknown deformation variables. Finally, we solved the equations to obtain a highly accurate estimation of three dimension deformation. Furthermore, an SS-DI experiment using Beidou-2 as transmitters was carried out to validate the proposed method, where a high accuracy(0.01 mm) device was utilized to simulate subsidence deformation. The experimental results reveal that the proposed method has better performance of spatial measurement accuracy of 0.53 mm compared with differential GPS method. | ZENG Tao ZHANG Tian TIAN WeiMing HU Cheng | 2015 | Science China(Information Sciences)2015，58，6： | 9 |
| 3 | High-precision deformation monitoring algorithm for GBSAR system: rail determination phase error compensation显示文摘In recent years, the repeat-pass GBSAR(ground based synthetic aperture radar) system has demonstrated its capacity to acquire deformation. Nevertheless, in a variety of applications, it needs to measure the deformation with the precision up to 0.1 mm, which could not be reached by utilizing the traditional PS(permanent scatterer) algorithm in most cases. Generally, one of the main reasons could be summarized into the phase error caused by the rail determination error, because the precision of rail determination might degrade during long working hours. However, the traditional PS algorithm could not compensate for the phase error caused by the rail determination error. In order to solve the problems, we modify the conventional PS algorithm.Firstly, we deduced the transformation relationship between the rail determination error and its corresponding interferometric phase error. Then, the phase errors caused by the atmosphere and the rail determination error were jointly compensated. The experimental data, which were obtained in Fangshan District in Beijing(China), were used to test and verify the performance of the new algorithm. After the comparison between the results processed by the new algorithm and those processed by the traditional algorithm, the proposed method demonstrated its ability to obtain high-precision deformation. | Cheng HU Mao ZHU Tao ZENG Weiming TIAN Cong MAO | 2016 | Science China(Information Sciences)2016，59，8： | 9 |
| 4 | Impacts of ionospheric scintillation on geosynchronous SAR focusing: preliminary experiments and analysis显示文摘亲爱的编辑,同步合成孔径雷达(GEO SAR)具有显着的潜在危害和灾害监测应用时,由于其短重访时间约24小时,约1 / 3的地球表面[1,2],覆盖面广。然而,在L波段操作使它更容易受到电离层闪烁[2,3]。徐等。从理论上分析了电离层对星载SAR球形闪烁[ 3 ]的影响,这一现象也被观察到在低地球轨道(LEO SAR)SARS如ALOS PALSAR [ 4 ]。地理合成孔径雷达是更严重的影响电离层闪烁,因为信号传播路径覆盖整个电离层(超过1000公里以上的地面)[ 3 ]。相比之下,狮子座合成孔径雷达的轨道是几百公里。然而,研究人员很少分析电离层闪烁对L波段GEO SAR,或进行实验验证。 | LI YuanHao HU Cheng DONG XiChao TIAN WeiMing LONG Teng | 2015 | Science China(Information Sciences)2015，58，10： | 8 |
| 5 | Diallyl trisulfide induces apoptosis and inhibits proliferation of A549 cells in vitro and in vivo显示文摘肺癌症是在整个世界的癌症相关的死亡的领先的原因。在最近的年里,肺的腺癌在频率超过了有鳞的房间癌并且是在许多国家的肺癌症的占优势的形式。流行病学的调查显示出在消费和死亡从许多癌症评估的大蒜(瞀或蒜之类 sativum ) 之间的一种反的关系。Diallyl trisulfide (DATS ) 是导出大蒜的混合物之一(是也知道:organosulfer 混合物,振荡) 。DATS 能导致 apoptosis 并且禁止许多癌症细胞线的生长。我们的学习证明 DATS 导致的 apoptotic 事件是通过导致了 Bax/Bcl-2 和 caspase-3, -8, 和 -9 的活动的比率的起来规定的 anti-apoptotic Bcl-2 的重要减少的线粒体依赖者 caspase 串联。最后, DATS 导致了 apoptosis 并且在一个集中依赖者和时间依赖者举止禁止了增长。由与 A549 异种皮移植建立女 BALB/c 裸体老鼠的一个动物模特儿,没有与控制组相比引起重量损失或任何另外的副作用,而且,我们在裸体老鼠发现 DATS 的那口头的 gavage A549 异种皮移植的显著地延迟的生长。在 vitro 并且在 vivo 的所有证据建议 DATS 能是理想的反癌症药。 | Wenjun Li Hui Tian Lin Li Shuhai Li Weiming Yue Zhitao Chen Lei Qi Wensi Hu Yingchao Zhu Bin Hao Cun Gao Libo Si Fei Gao | 2012 | Acta Biochimica et Biophysica Sinica2012，44，7： | 6 |
| 6 | Human mesenchymal stem cells with adenovirus-mediated TRAIL gene transduction have antitumor effects on esophageal cancer cell line Eca-109显示文摘apoptotic ligand TNF 相关的导致 apoptosis ligand (小道) 被相信是癌症 genetherapy 的一个有希望的候选人,然而,全身地处理这疾病的基因治疗策略被 thevector 的低效的交货经常损害到肿瘤组织。间充质的干细胞(MSC ) 被显示出到家到肿瘤地点并且能潜在地 actas 为 antitumor 基因治疗向量的盾和车辆。这里,我们使用了表示小道到 transduceMSCs 的 adenoviral 向量并且在食道的癌症房间 Eca-109 上学习了这些带小道的 MSC 的导致 apoptosis 活动。我们在 vitro,表示小道的 MSC 能禁止增长并且由 MTT 试金, co-cultureexperiments 和流动 cytometry 分析在 Eca-109 房间导致 apoptosis 的 resultsshowed。在 vivo,表示小道的 MSC 也显示了一个能力在一个 Eca-109 异种皮移植老鼠模型禁止肿瘤生长。一起, ourfindings 显示基于 MSCs 的小道基因交货的基因治疗策略为食道的癌症的 improvingthe 治疗有宽潜在的价值。 | Lin Li Fengling Li Hui Tian Weiming Yue Shuhai Li Guanqing Chen | 2014 | Acta Biochimica et Biophysica Sinica2014，46，6： | 5 |
| 7 | Feasibility study of inclined geosynchronous SAR focusing using Beidou IGSO signals显示文摘Dear editor,Geosynchronous synthetic aperture radar(GEO SAR)[1,2]has an inclined geosynchronous orbit of around 36000 km,which leads to its short revisit time of around 24 hours and a wide coverage of up to approximately one third of the Earth surface.Its long integration time guarantees the fine resolution.Thus,GEO SAR owns the promising capability of providing images with the high resolution, | Xichao DONG Cheng HU Weiming TIAN Tian ZHANG Yuanhao LI | 2016 | Science China Earth Sciences2016，59，12： | 5 |
| 8 | Grating lobes suppression method for stepped frequency GB-SAR system显示文摘A grating lobes suppression method for chirp-subpulse stepped frequency(CSSF) signals is proposed, which is applied to deformation monitoring using the ground based synthetic aperture radar(GB-SAR) system. This method is based on accurate estimation and correction of the phase and amplitude error along two dimensions(range and azimuth), i.e., the error estimation inside the subpulse(in-subpulse error) and across the stepped frequency subpulses(cross-subpulse error) of transmitted CSSF signals. Validated both with simulated data and experimental data recorded in the deformation monitoring campaign, it can be seen that the method as well as the relative conclusions can be fully and effectively applied to most of the stepped frequency systems. | Tao Zeng Cong Mao Cheng Hu Mao Zhu Weiming Tian Jingjing Ren | 2014 | Journal of Systems Engineering and Electronics2014，25，6： | 3 |
| 9 | Down-regulation of heparanase leads to the inhibition of invasion and proliferation of A549 cells in vitro and in vivo显示文摘Heparanase 是降级的哺乳动物的 endoglycosidase 在房间表面并且在细胞外的矩阵的 heparan 硫酸盐。heparanase 的表示在许多人的恶意的肿瘤被检测并且仔细把侵略,转移,和 angiogenesis 与肿瘤联系了。然而, heparanase 的特定的角色和它调整非小的房间肺癌症(NSCLC ) 的恶意的潜力的机制房间仍然保持不清楚。在现在的学习, heparanase 的表示在由 antisense oligodeoxynucleotide 的 NSCLC 房间线是下面调整的。结果证明 heparanase 的下面规定导致了重要抑制侵略并且在 vitro 并且在 vivo 的 A549 房间的 proliferative 潜力。进一步的研究证明 heparanase 的下面规定显著地禁止了 A549 房间的 angiogenic 潜力,它可能是为在在 vivo 的 BALB/c 裸体老鼠的 A549 房间增长的抑制负责的机制。这些调查结果证明 heparanase 在调整 A549 房间的侵略,增长,和 angiogenesis 起必要作用。 | Zhitao Chen Liangming Zhu Xiaohua Li Hui Tian Yusong Fang Haibo Liu Shuhai Li Lin Li Weiming Yue Wenjun Li | 2013 | Acta Biochimica et Biophysica Sinica2013，45，3： | 3 |
| 10 | Partition of GB-InSAR deformation map based on dynamic time warping and k-means显示文摘Ground-based interferometric synthetic aperture radar(GB-InSAR)can take deformation measurement with a high accuracy.Partition of the GB-InSAR deformation map benefits analyzing the deformation state of the monitoring scene better.Existing partition methods rely on labelled datasets or single deformation feature,and they cannot be effectively utilized in GBInSAR applications.This paper proposes an improved partition method of the GB-InSAR deformation map based on dynamic time warping(DTW)and k-means.The DTW similarities between a reference point and all the measurement points are calculated based on their time-series deformations.Then the DTW similarity and cumulative deformation are taken as two partition features.With the k-means algorithm and the score based on multi evaluation indexes,a deformation map can be partitioned into an appropriate number of classes.Experimental datasets of West Copper Mine are processed to validate the effectiveness of the proposed method,whose measurement points are divided into seven classes with a score of 0.3151. | TIAN Weiming DU Lin DENG Yunkai DONG Xichao | 2022 | Journal of Systems Engineering and Electronics2022，33，4： | 2 |
| 11 | Down-regulation of MTA1 protein leads to the inhibition of migration, invasion, and angiogenesis of non-small-cell lung cancer cell line显示文摘联系转移的蛋白质 1 (MTA1 ) 高表示在许多人的好攻击的肿瘤被检测了并且在象侵略,转移,和 angiogenesis 那样的恶意的生物行为起重要作用。然而,在调整 non-small-cell 肺癌症(NSCLC ) 的恶意的行为的 MTA1 蛋白质的特定的角色和机制房间仍然保持不清楚。阐明 MTA1 蛋白质的详细函数,我们下面调整在由在 vitro 的 RNA 干扰(RNAi ) 的 NSCLC 房间线的 MTA1 蛋白质表达式,并且发现 MTA1 蛋白质的下面规定显著地禁止了 95D 房间的移植和侵略潜力。进一步的研究表明 MTA1 蛋白质的下面规定显著地减少了矩阵 metalloproteinase-9 的活动,它能是为 95D 房间移植和侵略的抑制负责的机制。另外,试管形成试金证明 MTA1-siRNA 95D 房间的调节媒介导致的完全的试管的数字比 95D 房间的显著地小。这些调查结果证明那 MTA1 蛋白质在调整 95D 房间的迁居,侵略,和 angiogenesis 潜力起重要作用,由 RNAi 建议那条 MTA1 蛋白质下面规定可能是一条新奇治疗学的途径禁止 NSCLC 的前进。 | Shuhai Li Hui Tian Weiming Yue Lin Li Cun Gao Libo Si Wenjun Li Wensi Hu Lei Qi Ming Lu | 2013 | Acta Biochimica et Biophysica Sinica2013，45，2： | 2 |
| 12 | The Oil-Bearing Pore Size Distribution of Lacustrine Shale from E2S42 Sub-Member in Damintun Sag,Liaohe Depression,Bohai Bay Basin,China显示文摘1 Introduction There is a set of organic rich shale at E22S4sub-member in damnintun sag.The organic material is typically type I.In recent years,breakthrough was obtained in shale oil exploration.The wettability of organic and inorganic pore is different.As a result,the mobility of oil in organic and inorganic pore is different.So it’s necessary to | CHEN Guohui LU Shuangfang LI Jinbu WANG Weiming TIAN Shansi SHAN Junfeng HU Yingjie MAO Jinli HAN Xia | 2015 | Acta Geologica Sinica(English Edition)2015，89，A01： | 2 |
| 13 | Primary renal mucosa-associated lymphoid tissue lymphoma, the result of chronic pyelonephritis?显示文摘Objective: To report 2 cases of primary renal marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (MALT lymphoma), and observe the relations between this rare tumor of kidney and chronic pyelonephritis. Methods: 2 renal MALT lymphomas were collected from referral consultation. Detailed clinical information were reviewed, morphological analysis based on the HE section, and immunohistochemistry were performed by CD20, CD79a, CD5, CD10, CD43, CD23, BCL10 and Cyclin D1 antibodies. Results: 2 female patients with age of 48 and 55, respectively, all had a history of chronic pyelonephritis. Under the B ultrasonic and CT scanning a bump in the kidney was found. Renal carcinoma suspected and hereby the whole nephrectomy performed. In the macroscopic, tumors were laid in the renal medulla, with dark red color and ill-defined boundary. In the microscopic, there were mixed lymphoid cells infiltrate which mainly consisted of small lympho- cytes, centrocyte-like cells, lymphoplasmacytoid and plasma cells, reactive follicles and lymphoepithelial lesions also could be seen in the lesion, but follicles colonization was rare. In fact, except changes of lymphoma, basic renal disease also could be seen. Most glomeruli were atrophic, some glomeruli were hyperplastic and hypertrophic. Tubules were dilated or contacted, many dilated tubules contained pink-color glassy-appearing casts that suggest the appearance of thyroid tissue. As a result, those 2 cases showed juxtaposed changes of lymphoma and pyelonephritis. Immunohistochemistry showed that tumor cells were CD20 and CD79a positive, CD43 was weak positive, but CD5, CD10, CD23, BCL10 and Cyclin D1 were all negative. Conclusion: Primary renal MALT lymphoma was very rare disease. According to the clinical manifestation, it’s hard to differentiate from renal cell carcinoma. But the morphological features were consistent with the classic MALT lymphomas in other sites. Immunophenotypic profiles were helpful for diagnosis. Based on the truth that many MALT lymphomas in other sites were connected with chronic inflammations, we suppose that the renal MALT lymphoma may originate from chronic pyelonephritis. | Baizhou Li Weiming Zhang Xiuchun Tian Liang Qiu | 2008 | The Chinese-German Journal of Clinical Oncology2008，7，1： | 2 |
| 14 | Ef- fect of gufuhuo decoction on local apoptosis of steroid- induced necrosis of femoral head显示文摘 | Tian Weiming Wang Wenzhi Wang Xingguo | 2006 | Chinese journal of tra- ditional Chinese medicine2006，30，23： | 1 |
| 15 | An incremental dpmm-based method for trajectory clustering,modeling and retrieval显示文摘 | Hu Weiming Li Xi Tian Guodong | 2013 | IEEE Trans on Pattern Analysis and Machine Intelligence2013，35，5： | 1 |
| 16 | Technical Efficiency and Its Determinants in China’s Grain Production显示文摘 | Weiming Tian Guang Hua Wan | 2000 | Journal of Productivity Analysis2000，，2： | 1 |
| 17 | An improved hierarchica dirichlet process hidden markov mode显示文摘 | Hu Weiming Tian Guodong Li Xi | 2013 | International Journal of Computer Vision2013，105，3： | 1 |
| 18 | The Role of Organ Failure and Infection in Necrotizing Pancreatitis: A Prospective Study显示文摘 | Qiang Guo Ang Li Qing Xia Xubao Liu Bole Tian Gang Mai Zongwen Huang Guangyuan Chen Wenfu Tang Xiaodong Jin Weixia Chen Huimin Lu Nengwen KE Zhaoda Zhang Weiming HU | 2014 | Annals of Surgery2014，，6： | 1 |
| 19 | Application of Modified SPECAN Algorithm in Parasitical BiSAR显示文摘 | TIAN Weiming GAO Lining LONG Teng | | 0，，04： | 1 |
| 20 | Agricultural Reform in China显示文摘 | GUNASEKERA TIAN Weiming ZHAO Zhao | 1991 | Australian Bureau of Agricultural and Resource Economics1991，，4： | 1 |
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