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| 1 | Reversibility of minimal hepatic encephalopathy following liver transplantation in Egyptian cirrhotic patients显示文摘AIM To evaluate the reversibility of minimal hepatic encephalopathy(MHE) following liver transplantation(LT) in Egyptian cirrhotic patients. METHODS This prospective study included twenty patients with biopsy-proven liver cirrhosis listed for LT and twenty ageand sex-matched healthy control subjects. All underwent neuro-psychiatric examination, laboratory investigations, radiological studies and psychometric tests including trail making test A(TMT A), TMT B, digit symbol test and serial dotting test. The psychometric hepatic encephalopathy score(PHES) was calculated for patients to diagnose MHE. Psychometric tests were repeated six months following LT in the cirrhotic patient group. RESULTS Before LT, psychometric tests showed highly significant deficits in cirrhotic patients in comparison to controls(P < 0.001). There was a statistically significant improvement in test values in the patient group after LT; however, their values were still significantly worse than those of the controls(P < 0.001). The PHES detected MHE in 16 patients(80%) before LT with a median value of -7 ± 3.5. The median PHES value was significantly improved following LT, reaching-4.5 ± 5(P < 0.001), and the number of patients with MHE decreased to 11(55%). The pre-transplant model for end-stage liver disease(MELD) score ≥ 15 was significantly related to the presence of post-transplant MHE(P = 0.005). More patients in whom reversal of MHE was observed had a pre-transplant MELD score < 15.CONCLUSION Reversal of MHE in cirrhotic patients could be achieved by LT, especially in those with a MELD score < 15. | Mahmoud A Osman Moataz M Sayed Khaled A Mansour Shereen A Saleh Wesam A Ibrahim Sara M Abdelhakam Mohamed Bahaa Wael A Yousry Hosam S Elbaz Reginia N Mikhail Azza M Hassan Ehab H Elsayed Dalia A Mahmoud | 2016 | World Journal of Hepatology2016，8，30： | 11 |
| 2 | Hepatitis C virus:A global view显示文摘Hepatitis C virus(HCV) is a global challenge; 130-175 million are chronically infected. Over 350000 die each year from HCV. Chronic HCV is the primary cause of cirrhosis, hepatocellular carcinoma(HCC), and end-stage liver disease. Management of chronic HCV is aimed at preventing cirrhosis, reducing the risk of HCC, and treating extra hepatic complications. New treatments for chronic HCV has been devoted based on direct-acting antivirals, as pegylated interferon(peginterferon) is responsible for many side effects and limits treatment access. Sofosbuvir is the first compound to enter the market with Peginterferon-free combination regimens. | Amal Ahmed Mohamed Tamer A Elbedewy Magdy El-Serafy Naglaa El-Toukhy Wesam Ahmed Zaniab Ali El Din | 2015 | World Journal of Hepatology2015，7，26： | 7 |
| 3 | Duodenal variceal bleeding with large spontaneous portosystemic shunt treated with transjugular intrahepatic portosystemic shunt and embolization: A case report显示文摘BACKGROUND Duodenal variceal bleeding is a rare cause of gastrointestinal bleeding. The most common site is the duodenal bulb. It is usually detected endoscopically but it can be very challenging to diagnose if it is located distal to the second part od duodenum. The pre- transjugular intrahepatic portosystemic shunt (TIPS) presence of spontaneous portosystemic shunt (SPSS) was found to be associated with an increased risk of early morbidity and mortality after TIPS placement. CASE SUMMARY A 43-year-old cirrhotic male presented with melena for three days. Upper endoscopy was performed and showed active blood oozing from the distal duodenum concerning for ectopic duodenal varix. A computed tomography (CT) angiogram was performed and showed an enlarged cluster of venous collaterals around the distal duodenum. He underwent TIPS placement. He had another episode of melena three days later. Push enteroscopy with injection sclerotherapy into the duodenal varices was performed with no success. A repeat CT angiogram showed occluded TIPS shunt. Therefore, a TIPS revision was performed and there was an extensive portal venous thrombosis with a large shunt between the inferior mesenteric vein and left renal vein via the left gonadal vein. Thrombectomy and TIPS shunt balloon angioplasty was performed, followed by embolization of the portosystemic. The melena was resolved, and patient was discharged with arranged hepatology follow up. CONCLUSION It importance to look and embolize the SPSS shunts in patients with early TIPS dysfunction and recurrent duodenal variceal bleeding. | Rohit Anand Saad Emhmed Ali Driss Raissi Wesam M Frandah | 2019 | World Journal of Radiology2019，11，8： | 7 |
| 4 | Phytochemistry,pharmacology,and therapeutic uses of black seed(Nigella sativa)显示文摘Black seed(Nigella sativa) is an annual flowering plant from Ranunculaceae family, native to southwest Asia. This plant has many food and medicinal uses. The use of its seeds and oil is common for treatment of many diseases, including rheumatoid arthritis, asthma, inflammatory diseases, diabetes and digestive diseases. The purpose of this study was to provide a comprehensive review on the scientific reports that have been published about N. sativa. The facts and statistics presented in this review article were gathered from the journals accessible in creditable databases such as Science Direct, Medline, Pub Med, Scopus, EBSCO, EMBASE, SID and Iran Medex. The keywords searched in Persian and English books on medicinal plants and traditional medicine, as well as the above reputable databases were 'Black seed', 'Nigella sativa', 'therapeutic effect', and 'medicinal plant'. The results showed that N. sativa has many biological effects such as anti-inflammatory, anti-hyperlipidemic, anti-microbial, anti-cancer, anti-oxidant, anti-diabetic, anti-hypertensive, and wound healing activities. It also has effects on reproductive, digestive, immune and central nervous systems, such as anticonvulsant and analgesic activities. In summary, it can be used as a valuable plant for production of new drugs for treatment of many diseases. | Wesam Kooti Zahra Hasanzadeh-Noohi Naim Sharafi-Ahvazi Majid Asadl-Samani Damoon Ashtary-Larky | 2016 | Chinese Journal of Natural Medicines2016，14，10： | 5 |
| 5 | Optimization of biliary drainage in inoperable distal malignant strictures显示文摘BACKGROUND Given most patients with distal malignant biliary obstruction present in the nonresectable stage,palliative endoscopic biliary drainage with fully covered metal stent(FCMS)or uncovered metal stent(UCMS)is the only available measure to improve patients’quality of life.Half covered metal stent(HCMS)has been recently introduced commercially.The adverse effects and stent function between FCMS and UCMS have been extensively discussed.AIM To study the duration of stent patency of HCMS and compare it with FCMS and UCMS to optimize biliary drainage in inoperable patients with distal malignant obstruction.Secondary aims in our study included evaluation of patients’survival and the rates of adverse events for each type of stent.METHODS We studied 210 patients and randomized them into three equal groups;HCMS,FCMS and UCMS were inserted endoscopically.RESULTS Stent occlusion occurred in(18.6%,17.1%and 15.7%in HCMS,FCMS and UCMS groups,respectively,P=0.9).Stent migration occurred only in patients with FCMS(8.6%of patients).Cholangitis and cholecystitis occurred in 11.4%and 5.7%of patients,respectively,in FCMS.Tumor growth occurred only in 10 cases among patients with UCMS after a median of 140 d,sludge occurred in nine,seven and one patients in HCMS,FCMS and UCMS,respectively(P=0.04).CONCLUSION Given the prolonged stent functioning time,the use of HCMS is preferred over the use of UCMS and FCMS for optimizing biliary drainage in patients with distal malignant biliary obstruction. | Esam Elshimi Wesam Morad Omar Elshaarawy Ahmed Attia | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，9： | 5 |
| 6 | Corneal sensitivity,ocular surface health and tear film stability after punctal plug therapy of aqueous deficient dry eye显示文摘·AIM: To evaluate the effect of punctal occlusion using thermosensitive(smart plug) versus silicone plug for management of aqueous deficient dry eye on cornea sensitivity, ocular surface health and tear film stability.·METHODS: A comparative prospective interventiona case study included 45 patients with bilateral severe form of aqueous deficient dry eye. In each patient, the smar plug was inserted in the lower punctum of the right eye which was considered as study group 1 and silicone plug was inserted in the lower punctum of the left eye o the same patient which was considered as study group2. All patients were subjected to careful history taking and questionnaire for subjective assessment of severity of symptoms. Corneal sensitivity, corneal fluorescein rose bengal staining, Schirmer's I test, tear film break up time and conjunctival impression cytology were performed pre and 1, 3 and 6mo post plug insertion.·RESULTS: A statistically significant improvement in subjective and objective manifestations occurred following treatment with both types of plugs(P <0.01)The thermosensitive plug caused significant overal improvement, decrease in frequency of application o tear substitutes and improvement of conjunctiva impression cytology parameters in the inserted side(P <0.01). Canaliculitis was reported in two eyes(4.4% following punctal occlusion using thermosensitive plug(study group 1). Spontaneous plug loss occurred in 21eyes(46.6%) in the silicone plug group(study group 2).·CONCLUSION: Improvement of subjective and objective manifestations of aqueous deficient dry eye occurs following punctal plug occlusion. Thermosensitive plug has good patient's compliance with fewer complications and lower rates of loss compared to the silicone plug. | Azza Mohamed Ahmed Said Mona Elsayed Farag Tarek Mohamed Abdulla Othman Ali Othman Ziko Wesam Mohamed Osman | 2016 | International Journal of Ophthalmology(English edition)2016，9，11： | 4 |
| 7 | Survey of unmanned subterranean exploration,navigation,and localisation显示文摘Subsurface networks include mining tunnels,caves,and the urban underground.Each of these environments presents a complex setting with significant challenges in exploration,exploitation,etc.Multiple hazards exist,including environmental and structural,and conditions degrade and change temporally.We present a survey of research in autonomy,networking and mobility focused on exploring and/or mapping subsurface networks in unpredictable and unexplored environments.The focus is on mining tunnels as a proxy subterranean environment;motivated by the proximity of the authors to the Bonita Peak Mining District;a Superfund site consisting of 48 historic mines which have contaminated soil,groundwater and surface water with heavy metals as a result of historic practices.The exploration and assessment of the mining tunnels for remediation efforts presents an extremely challenging problem in subterranean navigation.Arguably,the environment in question is the most extreme and challenging subterranean environment.Unmanned assets must enter to explore and re-map the tunnels to assess safety for subsequent entrance by robots and/or humans for proper remediation.The survey is split into three categories--Locomotion,GPS-denied navigation and localization,and Communication.It is concluded with a proposed design for a platform that addresses the difficulties of exploring an abandoned mine. | Jeffrey Martz Wesam Al-Sabban Ryan N.Smith | 2020 | IET Cyber-Systems and Robotics2020，2，1： | 3 |
| 8 | N-butyl-2-cyanoacrylate, iso-amyl-2-cyanoacrylate and hypertonic glucose with 72% chromated glycerin in gastric varices显示文摘AIM: To compare n-butyl-2-cyanoacrylate, iso-amyl-2-cyanoacrylate and a mixture of 72% chromated glycerin with hypertonic glucose solution in management of gastric varices. METHODS: Ninety patients with gastric varices presented to Endoscopy Unit of Ain Shams University Hospital were included. They were randomly allocated into three groups; each group included 30 patients treated with intravariceal sclerosant injections in biweekly sessions till complete obturation of gastric varices; Group I(n-butyl-2-cyanoacrylate; Histoacryl), Group II(iso-amyl-2-cyanoacrylate; Amcrylate) and Group III(mixture of 72% chromated glycerin; Scleremo with glucose solution 25%). All the procedures were performed electively without active bleeding. Recruited patients were followed up for 3 mo. RESULTS: 26% of Scleremo group had bleeding during puncture vs 3.3% in each of the other two groups with significant difference,(P < 0.05). None of Scleremo group had needle obstruction vs 13.3% in each of the other two groups with no significant difference,(P > 0.05). Rebleeding occurred in 13.3% of Histoacryl and Amcrylate groups vs 0% in Scleremo group with no significant difference. The in hospital mortality was 6.6% in both Histoacryl and Amcrylate groups, while it was 0% in Scleremo group with no significant difference. In the first and second sessions, the amount of Scleremo needed for obturation was significantly high, while the amount of Histoacryl was significantly low. Scleremo was the less costly of the two treatments. CONCLUSION: All used sclerosant substances showed efficacy and success in management of gastric varices with no significant differences except in total amount, cost and bleeding during puncture. | Reda Elwakil Mohamed Fawzy Montasser Sara M Abdelhakam Wesam A Ibrahim | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，4： | 3 |
| 9 | Maternal vitamin D level and vitamin D receptor gene polymorphism as a risk factor for congenital heart diseases in offspring;An Egyptian case-control study显示文摘Vitamin D&vitamin D receptor(VDR)signaling play a very crucial role in early embryonic heart development.We construct this case-control study to investigate the association between maternal serum vitamin D level&VDR gene Fok1 polymorphism and risk of congenital heart defects(CHD)in offspring.Fifty mothers who had term neonates with CHD were considered as cases.Fifty age-comparable healthy mothers who had neonates without CHD were contemplated as controls.Maternal serum 25 hydroxyvitamin D[25(OH)D]level was tested using ELISA.Maternal VDR gene Fok1 polymorphism was analyzed using PCR-based RFLP-assay.There was a significant decrease in maternal vitamin D level(P=0.002)and a significant increase in vitamin D deficient status(P=0.007)among cases when compared to controls.VDR gene Fok1 genotypes distribution frequency were in accordance with Hardy Weinberg equilibrium(HW)among controls.A significant increase in VDR gene Fok1 F/f&f/f genotypes and f allele were observed in cases compared to controls with estimated odds ratio(95%confidence interval)&P-value of 3(1e8)&P=0.006,11(1e97)&P=0.01 and 3(2e6)&P=0.001 respectively.There was a significant decrease in maternal vitamin D level in neonates with cyanotic CHD(P=0.000)compared to those with a cyanotic CHD while there was no significant difference in VDR Fok1 genotype(P=0.18)&allele(P=0.05)distribution between two groups.We concluded that maternal vitamin D deficiency and VDR gene Fok1 F/f,f/f genotype and f allele were associated with increased risk of CHD in offspring. | Wesam A.Mokhtar Amal Fawzy Reem M.Allam Rania M.Amer Mona S.Hamed | 2019 | Genes & Diseases2019，6，2： | 2 |
| 10 | Left Ventricular Assist Devices and Gastrointestinal Bleeding: A Narrative Review of Case Reports and Case Series显示文摘 | Sameer Islam Cihan Cevik Rosalinda Madonna Wesam Frandah Ebtesam Islam Sherazad Islam Kenneth Nugent | 2013 | Clin Cardiol2013，，： | 2 |
| 11 | DDB2, DDB 1 A and DET1 exhibit complex interactions during Arabidopsis development 显示文摘 | Wesam M A K Dana F S | 2007 | Genetics2007，176，： | 1 |
| 12 | Efficient Data Clustering Algorithms: Improvements over K-means 显示文摘 | Mohamed Abubaker Wesam Ashour | 2013 | International Journal of Intelligent Systems and Applications2013，5，3： | 1 |
| 13 | A young woman with pulmonary hemorrhage and hypoxic respiratory failure 显示文摘 | Rakesh VA Wesam JY | 2010 | Chest2010，137，2： | 1 |
| 14 | Performance evaluation of multieast ad hoe on-demand distance vector protocol显示文摘 | Wesam AL Mobaideen Hani Mahmoud Mimi | 2007 | Computer Communications2007，30，9： | 1 |
| 15 | Cadmium, copper and zinc toxicity effects on growth, proline content and genetic stability of Solanum nigrum L,a crop wild relative for tomato comparative study显示文摘 | Wesam Khateeb HajerAl -- Qwasemeh | 2014 | Physiology and Molecular Biology of Plants2014，20，1： | 1 |
| 16 | A clinical study on the effects of cordless and conventional retraction techniques on the gingival and periodontal health 显示文摘 | Khaled QH Wesam ZA Alwaeli HA | 2008 | Journal of Clinical Periodontol- ogy2008，35，12： | 1 |
| 17 | An Orbit Determination Using SGP4 Propagator and Doppler Shifts for CubeSats显示文摘The two line elements(TLEs),released by the North American Aerospace Defense Command(NORAD),are chosen for CubeSats' mission operators.Unfortunately,they have errors and other accompanied problems,which cause large deviations in the in-track component.When a TLE value is available at a certain epoch,the dominant error is the angular error.It is proposed to correct the angular error by solving-for the mean argument of latitude at the desired epoch.A batch least squares technique and range rate measurements are used for the correction process.With the assistance of satellite tool kit(STK)software and Matlab,a simulation to verify the orbit determination(OD)technique is implemented.This paper provides an angular correction low cost OD method and presents a complete analysis for various test cases.This approach maintains high accuracy in cross-track and radial and makes great improvement in in-track at the same time,but it is exclusive for circular orbits.When it is applied to an elliptical orbit,the error will be unacceptable.Therefore,the angular error is corrected using the longitude of periapsis which totally mitigates the error at the epoch under consideration.For inclinations less than 20 o,the mean longitude is preferred for the angular correction as it provides more accuracy compared with the mean argument of latitude. | Wesam M.Elmahy Zhang Xiang Lu Zhengliang Liao Wenhe | 2018 | Transactions of Nanjing University of Aeronautics and Astronautics2018，35，3： | 1 |
| 18 | PlexinD1 Glycoprotein Controls Migration of Positively Selected Thymocytes into the Medulla显示文摘 | Young I. Choi Jonathan S. Duke-Cohan Wesam B. Ahmed Maris A. Handley Fanny Mann Jonathan A. Epstein Linda K. Clayton Ellis L. Reinherz | 2008 | Immunity2008，，： | 1 |
| 19 | Impact of biliary complications on quality of life in live-donor liver transplant recipients显示文摘BACKGROUND Despite significant advancements in liver transplantation(LT)surgical procedures and perioperative care,post-LT biliary complications(BCs)remain a significant source of morbidity,mortality,and graft failure.In addition,data are conflicting regarding the health-related quality of life(HRQoL)of LT recipients.Thus,the success of LT should be considered in terms of both the survival and recovery of HRQoL.AIM To assess the impact of BCs on the HRQoL of live-donor LT recipients(LDLT-Rs).METHODS We retrospectively analysed data for 25 LDLT-Rs who developed BCs post-LT between January 2011 and December 2016 at our institution.The Short Form 12 version 2(SF 12v2)health survey was used to assess their HRQoL.We also included 25 LDLT-Rs without any post-LT complications as a control group.RESULTS The scores for HRQoL of LDLT-Rs who developed BCs were significantly higher than the norm-based scores in the domains of physical functioning(P=0.003),role-physical(P<0.001),bodily pain(P=0.003),general health(P=0.004),social functioning(P=0.005),role-emotional(P<0.001),and mental health(P<0.001).No significant difference between the two groups regarding vitality was detected(P=1.000).The LDLT-Rs with BCs had significantly lower scores than LDLT-Rs without BCs in all HRQoL domains(P<0.001)and the mental(P<0.001)and physical(P=0.0002)component summary scores.CONCLUSION The development of BCs in LDLT-Rs causes a lower range of improvement in HRQoL. | Reginia Nabil Guirguis Ehab Hasan Nashaat Azza Emam Yassin Wesam Ahmed Ibrahim Shereen A Saleh Mohamed Bahaa Mahmoud El-Meteini Mohamed Fathy Hany Mansour Dabbous Iman Fawzy Montasser Manar Salah Ghada Abdelrahman Mohamed | 2021 | World Journal of Hepatology2021，13，10： | 1 |
| 20 | A Vibration Method for Discovering Density Varied Clusters显示文摘 | Mohammad T. Elbatta Raed M. Bolbol Wesam M. Ashour Z. He J. A. Hernandez | 2011 | ISRN Artificial Intelligence2011，，： | 1 |
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