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| 1 | Treatment strategies in obstructed defecation and fecal incontinence显示文摘妨碍的澄清(OD ) 和大便失禁(FI ) 正在质问临床的问题,它通常在颜色的实践被遇到表面的外科医生和胃的肠学。这些混乱社会上并且心理上地沮丧病人并且极大地损害他们生命的质量。位于下面解剖并且 pathophysiological 变化是复杂的,不完全地经常理解并且不能总是被决定。作为后果,许多医药、外科、行为的途径被描述了,没有灵丹妙药。在过去的十年,在一理解和在肛门直肠的生理学实验室(ARP ) 的评估的合理、类似的方法的混乱,辐射学研究,和新外科的技术导致了有希望的结果这些进展。在这简短评论,我们在妨碍的澄清和大便失禁的临床、治疗学的方面上讨论治疗策略和最近的更改。 | Marat Khaikin Steven D Wexner | 2006 | World Journal of Gastroenterology2006,12,20: | 15 |
| 2 | Current status of laparoscopy for the treatment of rectal cancer显示文摘Surgery for rectal cancer in complex and entails many challenges.While the laparoscopic approach in general and specific to colon cancer has been long proven to have short term benefits and to be oncologically safe,it is still a debatable topic for rectal cancer.The attempt to benefit rectal cancer patients with the known advantages of the laparoscopic approach while not compromising their oncologic outcome has led to the conduction of many studies during the past decade.Herein we describe our technique for laparoscopic proctectomy and assess the current literature dealing with short term outcomes,immediate oncologic measures(such as lymph node yield and specimen quality) and long term oncologic outcomes of laparoscopic rectal cancer surgery.We also briefly evaluate the evolving issues of robotic assisted rectal cancer surgery and the current innovations and trends in the minimally invasive approach to rectal cancer surgery. | Noam Shussman Steven D Wexner | 2014 | World Journal of Gastroenterology2014,20,41: | 13 |
| 3 | Neutropenic enterocolitis显示文摘Neutropenic colitis is a severe condition usually affecting immunocompromised patients. Its exact pathogenesis is not completely understood. The main elements in disease onset appear to be intestinal mucosal injury together with neutropenia and the weakened immune system of the afflicted patients. These initial conditions lead to intestinal edema, engorged vessels, and a disrupted mucosal surface, which becomes more vulnerable to bacterial intramural invasion. Chemotherapeutic agents can cause direct mucosal injury(mucositis) or can predispose to distension and necrosis, thereby altering intestinal motility. This article aims to review current concepts regarding neutropenic colitis' pathogenesis, diagnosis, and management. | Fabio G Rodrigues Giovanna Dasilva Steven D Wexner | 2017 | World Journal of Gastroenterology2017,23,1: | 10 |
| 4 | 低位直肠癌保肛手术的现状与争议显示文摘在过去的一个世纪里,直肠癌外科获得了巨大的发展,手术方式也发生明显变化。从最初多数患者只能接受经会阴姑息切除发展到根治性的经腹会阴联合切除(APR)^[1-2],直到现代认识到全直肠系膜切除术(TME)的重要性^[3]。对直肠癌生物学行为的理解更深入,使距齿状线5cm以内,甚至距肛缘5cm以内的直肠肿瘤可安全地行保肛手术。随着手术方式的改进,术后局部复发率也明显下降。 | Steven D. Wexner Badma Bashankaev | 2009 | 中华外科杂志2009,47,13: | 10 |
| 5 | Idiopathic fistula-in-ano显示文摘Fistula-in-ano is the most common form of perineal sepsis.Typically,a fistula includes an internal opening,a track,and an external opening.The external opening might acutely appear following infection and/or an abscess,or more insiduously in a chronic manner.Management includes control of infection,assessment of the fistulous track in relation to the anal sphincter muscle,and finally,definitive treatment of the fistula.Fistulotomy was the most commonly used mode of management,but concerns about post-fistulotomy incontinence prompted the use of sphincter preserving techniques such as advancement flaps,fibrin glue,collagen fistula plug,ligation of the intersphincteric fistula track,and stem cells.Many descriptive and comparative studies have evaluated these different techniques with variable outcomes.The lack of consistent results,level I evidence,or long-term follow-up,as well as the heterogeneity of fistula pathology has prevented a definitive treatment algorithm.This article will review the most commonly available modalities and techniques for managing idiopathic fistula-in-ano. | Sherief Shawki Steven D Wexner | 2011 | World Journal of Gastroenterology2011,17,28: | 7 |
| 6 | 美国白人与中国人原发性结直肠癌病理特点对照显示文摘目的 比较研究美国白人与中国患者原发性结直肠癌 (CRC)的病理学特征。方法 回顾性分析 1990~ 2 0 0 0年美国克里夫兰佛罗里达临床中心结直肠外科 6 90例和中国第一军医大学南方医院普外科 870例连续完整的CRC患者资料。结果 美国白人与中国患者比较 :36 .3%比 2 6 .0 %的肿瘤位于近侧 (右侧 )结肠 (P <0 .0 0 1) ,6 3.7%比 74 .0 %位于远侧 (左侧 )结肠 (P <0 .0 0 1) ;中位年龄 72比5 4岁 (P <0 .0 0 1) ;腺癌 84 .3%比 85 .3% ,黏液腺癌 13.6 %比 11.4 % ,印戒细胞癌 1.5 %比 2 .7% ,腺鳞癌 0 .6 %比 0 .6 % (P >0 .0 5 ) ;高分化癌 16 .7%比 4 0 .2 % ,中分化 6 1.9%比 4 8.5 % ,低分化 2 1.4 %比11.3% (P <0 .0 0 1) ,近侧结肠癌中低分化比例在两种族患者中均较高 ;TNM分期 ,0期 5 .4 %比 1.3%(P <0 .0 0 1) ,Ⅰ期 34.8%比 18.9% (P <0 .0 0 1) ,Ⅱ期 2 9.9%比 33.2 % (P >0 .0 5 ) ,Ⅲ期 2 0 .3%比2 2 .8% (P >0 .0 5 ) ,Ⅳ期 9.6 %比 17.0 % (P <0 .0 0 1)。进展期癌更常见于近侧结肠和中国患者。结论 美国白人易患近侧结肠癌 ,中国患者远侧结直肠癌更常见 ,进展期比例高 ,年龄明显小。低分化和进展期癌更常见于近侧结肠。 | 卿三华 饶开运 蒋会勇 Wexner SD | 2003 | 中华消化杂志2003,23,5: | 7 |
| 7 | What every gastroenterologist needs to know about common anorectal disorders显示文摘Anorectal complaints are very common and are caused by a variety of mostly benign anorectal disorders.Many anorectal conditions may be successfully treated by primary care physicians in the outpatient setting,but patients tend not to seek medical attention due to embarrassment or fear of cancer.As a result,patients frequently present with advanced disease after experiencing significant decreases in quality of life.A number of patients with anorectal complaints are referred to gastroenterologists.However,gastroenterologists' knowledge and experience in approaching these conditions may not be sufficient.This article can serve as a guide to gastroenterologists to recognize,evaluate,and manage medically or non-surgically common benign anorectal disorders,and to identify when surgical referrals are most prudent.A review of the current literature is performed to evaluate comprehensive clinical pearls and management guidelines for each topic.Topics reviewed include hemorrhoids,anal fissures,anorectal fistulas and abscesses,and pruritus ani. | Moonkyung Cho Schubert Subbaramiah Sridhar Robert R Schade Steven D Wexner | 2009 | World Journal of Gastroenterology2009,15,26: | 5 |
| 8 | A constipation scoring system to simplify evaluation and management of constipated patients显示文摘 | Dr. Feran Agachan M.D. Teng Chen M.D. Johann Pfeifer M.D. Petachia Reissman M.D. Steven D. Wexner M.D | 1996 | Diseases of the Colon & Rectum1996,,6: | 4 |
| 9 | Etiology and management of fecal incontinence显示文摘 | J. Marcio N. Jorge Steven D. Wexner | 1993 | Diseases of the Colon & Rectum1993,,1: | 4 |
| 10 | Current management of fecal incontinence:Choosing amongst treatment options to optimize outcomes显示文摘The severity of fecal incontinence widely varies and can have dramatic devastating impacts on a person’s life.Fecal incontinence is common,though it is often underreported by patients.In addition to standard treatment options,new treatments have been developed during the past decade to attempt to effectively treat fecal incontinence with minimal morbidity.Non-operative treatments include dietary modifications,medications,and biofeedback therapy.Currently used surgical treatments include repair(sphincteroplasty),stimulation(sacral nerve stimulation or posterior tibial nerve stimulation),replacement(artificial bowel sphincter or muscle transposition)and diversion(stoma formation).Newer augmentation treatments such as radiofrequency energy delivery and injectable materials,are minimally invasive tools that may be good options before proceeding to surgery in some patients with mild fecal incontinence.In general,more invasive surgical treatments are now reserved for moderate to severe fecal incontinence.Functional and quality of life related outcomes,as well as potential complications of the treatment must be considered and the treatment of fecal incontinence must be individualized to the patient.General indications,techniques,and outcomes profiles for the various treatments of fecal incontinence are discussed in detail.Choosing the most effective treatment for the individual patient is essential to achieve optimal outcomes in the treatment of fecal incontinence. | Julie Ann M Van Koughnett Steven D Wexner | 2013 | World Journal of Gastroenterology2013,19,48: | 3 |
| 11 | Prospective, randomized, endoscopic-blinded trial comparing precolonoscopy bowel cleansing methods显示文摘 | Stephen M. Cohen M.D. Steven D. Wexner M.D. Sander R. Binderow M.D. Juan J. Nogueras M.D. Norma Daniel R.N. Eli D. Ehrenpreis M.D. Jonathan Jensen M.D. Gregory F. Bonner M.D. William B. Ruderman M.D | 1994 | Diseases of the Colon & Rectum1994,,7: | 2 |
| 12 | Laparoscopicvs. open abdominoperineal resection for cancer显示文摘 | James W. Fleshman M.D. Steven D. Wexner M.D. Mehran Anvari Ph.D M.D. Jean-Francois LaTulippe M.D. Elisa H. Birnbaum M.D. Ira J. Kodner M.D. Thomas E. Read M.D. Juan J. Nogueras M.D. Eric G. Weiss M.D | 1999 | Diseases of the Colon & Rectum1999,,7: | 2 |
| 13 | A constipation scoring system to simplify evaluation and management of constipated patients显示文摘 | Feran Agachan Teng Chen Johann Pfeifer Petachia Reissman Steven D. Wexner | 1996 | Diseases of the Colon & Rectum1996,,: | 2 |
| 14 | Patient and surgeon ranking of the severity of symptoms associated with fecal incontinence显示文摘 | Todd H. Rockwood James M. Church James W. Fleshman Robert L. Kane Constantinos Mavrantonis Alan G. Thorson Steven D. Wexner Donna Bliss R.N. Ann C. Lowry | 1999 | Diseases of the Colon & Rectum1999,,12: | 2 |
| 15 | Perfusion Assessment in Laparoscopic Left Sided/Anterior Resection (PILLAR) II: A Multi-Institutional Study显示文摘 | Mehraneh D. Jafari Steven D. Wexner Joseph E. Martz Elisabeth C. McLemore David A. Margolin Danny A. Sherwinter Sang W. Lee Anthony J. Senagore Michael J. Phelan Michael J. Stamos | 2014 | Journal of the American College of Surgeons2014,,: | 2 |
| 16 | Compression anastomosis: history and clinical considerations显示文摘 | Orit Kaidar-Person Raul J. Rosenthal Steven D. Wexner Samuel Szomstein Benjamin Person | 2008 | The American Journal of Surgery2008,,6: | 2 |
| 17 | Gracilis muscle interposition for the treatment of rectourethral, rectovaginal, and pouch-vaginal fistulas: results in 53 patients显示文摘 | Wexner SD Ruiz DE Genua J | 2008 | Ann Surg2008,248,1: | 1 |
| 18 | Port site metastases after laparoscopic colorectal surgery for cure of malignancy 显示文摘 | Wexner SD Cohen SM | 1995 | Br J Surg1995,82,3: | 1 |
| 19 | Sacral nerve stimula- tion for fecal incontinence显示文摘 | Takano S Boutros M Wexner SD | 2013 | Dis Colon Rectum2013,56,: | 1 |
| 20 | Local resection of rectal cancer 显示文摘 | Potenti F Wexner SD | 2000 | Hepat2ogestroenterology2000,47,32: | 1 |