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| 1 | Preservation solutions used during abdominal transplantation:Current status and outcomes显示文摘Organ preservation remains an important contributing factor to graft and patient outcomes. During donor organ procurement and transportation, cellular injury is mitigated through the use of preservation solutions in conjunction with hypothermia. Various preservation solutions and protocols exist with widespread variability among transplant centers. In this review of abdominal organ preservation solutions, evolution of transplantation and graft preservation are discussed followed by classification of preservation solutions according to the composition of electrolytes, impermeants, buffers, antioxidants, and energy precursors. Lastly, pertinent clinical studies in the setting of hepatic, renal, pancreas, and intestinal transplantation are reviewed for patient and graft survival as well as financial considerations. In liver transplants there may be some benefit with the use of histidine-tryptophan-ketoglutarate(HTK) over University of Wisconsin solution in terms of biliary complications and potential cost savings. Renal grafts may experience increased initial graft dysfunction with the use of Euro-Collins thereby dissuading its use in support of HTK which can lead to substantial cost savings. University of Wisconsin solution and Celsior are favored in pancreas transplants given the concern for pancreatitis and graft thrombosis associated with HTK. No difference was observed with preservation solutions with respect to graft and patient survival in liver, renal, and pancreas transplants. Studies involving intestinal transplants are sparse but University of Wisconsin solution infused intraluminally in combination with an intra-vascular washout is a reasonable option until further evidence can be generated. Available literature can be used to ameliorate extensive variation across centers while potentially minimizing graft dysfunction and improving associated costs. | Nicholas Latchana Joshua R Peck Bryan A Whitson Mitchell L Henry Elmahdi A Elkhammas Sylvester M Black | 2015 | World Journal of Transplantation2015，5，4： | 5 |
| 2 | Animal models of ex vivo lung perfusion as a platform for transplantation research显示文摘Ex vivo lung perfusion(EVLP) is a powerful experimental model for isolated lung research. EVLP allows for the lungs to be manipulated and characterized in an external environment so that the effect of specific ventilation/perfusion variables can be studied independent of other confounding physiologic contributions. At the same time,EVLP allows for normal organ level function and real-time monitoring of pulmonary physiology and mechanics. As a result,this technique provides uniqueadvantages over in vivo and in vitro models. Small and large animal models of EVLP have been developed and each of these models has their strengths and weaknesses. In this manuscript,we provide insight into the relative strengths of each model and describe how the development of advanced EVLP protocols is leading to a novel experimental platform that can be used to answer critical questions in pulmonary physiology and transplant medicine. | Kevin Nelson Christopher Bobba Samir Ghadiali Don Hayes Jr Sylvester M Black Bryan A Whitson | 2014 | World Journal of Experimental Medicine2014，4，2： | 2 |
| 3 | Melatonin and cortisoI assessment of circadian shifts in astronauts be- fore flight 显示文摘 | Whitson P A Putcha L Chen Y M | 1995 | Journal of Pineal Research1995，18，3： | 1 |
| 4 | Video-assisted thoracoscopic surgery is more favorable than thoracotomy for resection of clinical stageⅠnon-small cell lung cancer显示文摘 | Whitson B A Andrade R S Boettcher A | 2007 | Ann Thorae Surg2007，83，6： | 1 |
| 5 | Video-assisted thoracoscopic surgery is more favorable than shoraeotomy for resection of clinical stage I non-small cell lung cancer显示文摘 | Whitson B A Andrade R S Boettcher A | 2007 | Ann Thorae Surg2007，83，6： | 1 |
| 6 | Surgery for early-stage non-small cell lung cancer:a systematic review of the video-assisted thoracoscopic surgery versus thoracotomy approaches to lobectomy显示文摘 | Whitson B A Groth S S Duval S J | 2008 | Ann Thorac Surg2008，86，6： | 1 |
| 7 | Adipokine Response in Diabetics and Nondiabetics Following the Roux-en-Y Gastric Bypass:A Preliminary Study显示文摘 | Bryan A Whitson Daniel B | 2007 | Journal of Surgical Research2007，142，： | 1 |
| 8 | Video-assisted thoracic surgery is more favorable than thoracotomy for re- section of clinical stage no-small cell lung cancer显示文摘 | Whitson BA Andrads RS Boettcher A | 2007 | Ann Thorac Surg2007，83，6： | 1 |
| 9 | Machinery and crop selection with weather risk显示文摘 | Whitson R E Kay R D Lepori W A | 1981 | Transactions of the ASAE1981，24，2： | 1 |
| 10 | Thoracoscopic versus thoracotomy approaches to lobectomy:differential impairment of cellular immunity显示文摘 | Whitson B A DCunha J Andfade R S | 2008 | Ann Thorac Surg2008，86，6： | 1 |
| 11 | A multicolour fluorescence in situ hybridization test predicts recurrence in patients with high-risk superficial bladder tumours undergoing intravesical therapy 显示文摘 | Whitson J Berry A Carroll P | 2009 | BJU Int2009，104，3： | 1 |
| 12 | Video-assisted thoracic surgery is more favorable than thoraeotomy for resection of clinical stage no-small cell lung cancer 显示文摘 | Whitson BA Andrads RS Boettcher A | 2007 | Ann Thorac Surg2007，83，6： | 1 |
| 13 | Surgical assessment and intraoperative management of mediastinal lymph nodes in non small cell lung cancer显示文摘 | Whitson B A Groth S S Maddaus M A | 2007 | Ann Thorac Surg2007，84，3： | 1 |
| 14 | Surgery for early-stage non-small cell lung cancer:a systematic review of the video-assisted thoracoscopic surgery versus thoracotomy approaches to lobectomy 显示文摘 | Bryan A Whitson BA Shawn S | 2008 | Ann Thorac Surg2008，86，6： | 1 |
| 15 | Video-assisted thoracoscopic surgery is more favorable than thoracotomy for resection of clinical stage I non-small cell lung cancer显示文摘 | Whitson BA Andrade RS Boettcher A | 2007 | Ann Thorac Surg2007，83，6： | 1 |
| 16 | Renal stone risk assessment during shuttle flights 显示文摘 | Whitson P A Pietrzyk R A Pak C Y | 1997 | J Urology1997，158，6： | 1 |
| 17 | Video-assisted thoracoscopic surgery is more favorable than thoracotomy for resection of clinical stage I non-small lung cancer显示文摘 | Whitson BA Andrade RS Boettcher A | 2007 | Ann Thorac surg2007，83，6： | 1 |
| 18 | Laparoscopic resection of periaortic paragangliomas显示文摘 | Whitson B A Tuttle T M | 2005 | Am Surg2005，71，： | 1 |
| 19 | Resolving factor analysis显示文摘 | Mason C Maeder M Whitson A | 2001 | Anal Chem2001，73，7： | 1 |
| 20 | Video-assisted thoracoscopic surgery is more favorable than thoracotomy for resection of clinical stage I non-small cell lung cancer显示文摘 | Whitson BA Andrade RS Boetteher A | 2007 | Ann Tborac Surg2007，83，6： | 1 |
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