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90篇 您的检索式:作者名="Wijmenga"
    题名 作者 年代 出处 被引量
1Pharmacomicrobiomics: a novel route towards personalized medicine?显示文摘在药反应的内部个人的异质是影响病人幸福并且在社会水平上提出庞大的临床、金融的负担的一个严重问题。Pharmacogenomics 在关于药反应可变性或药毒性的对单个基因背景的影响的研究的最前线,并且最近,内脏 microbiome,也被称为第二个染色体,在这个方面作为一个重要播放器被认出了。而且, microbiome 是为由于机会改进药功效和安全操作它的作文的一个很吸引人的目标。Pharmacomicrobiomics 是调查 microbiome 变化和药反应和布置(吸收,分发,新陈代谢和排泄) 的相互影响的一个新兴的领域。在这评论,我们提供历史的概述并且在在内脏 microbiome,主人和药之间的复杂相互作用上检验当前的最先进的知识。我们主张那联合 pharmacogenomics 和 pharmacomicrobiomics 将为在个性化的药做主要进展提供一个重要基础。Marwah Doestzada Arnau Vich Vila Alexandra Zhernakova Debby P.Y. Koonen Rinse K. Weersma Daan J. TOUW Folkert Kuipers Cisca Wijmenga Jingyuan Fu 2018Protein & Cell2018,9,5:7
2Molecular pathogenesis of Wilson and Menkes disease:correlation of mutations with molecular defects and disease phenotypes 显示文摘De Bie P Muller P Wijmenga C 2007J Med Genet2007,44,11:1
3Genetics of intracranial aneurysms显示文摘Ruigrok YM Rinkel GJ Wijmenga C 2005Lancet Neurol2005,4,3:1
4Molecular pathogenesis of Wilson and Menkes disease : correlation of mutations with molecular defects and disease phenotypes 显示文摘de Bie P Muller P Wijmenga C 2007J Med Genet2007,44,11:1
5Genetic mapping ot the dentmogenesm lmpertecta type Ⅱ locus 显示文摘Crosby A H Scherpbier-Heddema T Wijmenga C 1995Am dHum Genet1995,57,4:1
6Protracted dislocation of the temporomandibular joint 显示文摘 Boering G Blankestijn J 1986Int J Oral Maxillofac Surg1986,15,4:1
7Meta - analyses on sus- pected chronic obstructive pulmonary disease genes : a summary of 20 years' research 显示文摘Smolonska J Wijmenga C Postma DS 2009Am J Respir Crit Care Med2009,180,7:1
8Molecular pathogenesis of the chromosome 16 inversion in the M4E0 subtype of acute myeloid leukemia显示文摘Liu P P Hajra A Wijmenga C 1995Blood1995,85,9:1
9Anticipation and phynotype in familial intracranial aneurysms 显示文摘Ruigrok YM Rinkel GJ Wijmenga C 2004J Neurosurg Psychiatry2004,75,10:1
10Meta - analyses on sus- pected chronic obstructive pulmonary disease genes: A summary of 20 years' research 显示文摘Smolonska J Wijmenga C Postma DS 2009Am J Respir Crit Care Med2009,180,7:1
11Genetic variation in Toll-like receptors and disease susceptibility显示文摘Netea MG Wijmenga C O'Neill LA 0,,:1
12Shared genetics in eoeliac disease and other immune-mediated diseases显示文摘Gutierrez-Achury J Coutinho de Almeida R Wijmenga C 2011Internal Medicine2011,269,6:1
13Metaanalyses on suspected chronic obstructive pulmonary disease genes:a summary of 20 years' research显示文摘SMOLONSKA J WIJMENGA C POSTMA DS 2009Am J Respir Crit Care Med2009,180,:1
14Detecting shared pathogenesis from the shared genetics of immune- related diseases显示文摘Zhernakova A van Diemen CC Wijmenga C 2009Nat Rev Genet2009,10,1:1
15Gene expression studies in cells from primary ciliary dyskinesia patients identify 208 potential ciliary genes显示文摘Geremek M Bruinenberg M Zie tkiewicz E Pogorzelski A Witt M Wijmenga C 2011Hum Genet2011,129,7:1
16Chromosome 4q DNA rearrangements associated with facioscapulohumeral muscular dystrophy显示文摘Wijmenga C Hewitt JE Sandkuijl LA 1992Nature Genetics1992,2,1:1
17Molecular regulation of copper excretion in the liver 显示文摘Wijmenga C Klomp L W 2004Proc Nutr Soc2004,63,1:1
18家族性颅内动脉瘤的预测和表型Ruigrok Y.M. Rinkel G.J.E. Wijmenga C. Van GijnJ. 夏峰 2005世界核心医学期刊文摘(神经病学分册)2005,0,2:1
19Detecting shared pathogenesis from the shared genetics of immune-related diseases 显示文摘Zhemakova A van Diemen CC Wijmenga C 2009Nat Rev Genet2009,10,1:1
20Meta-analyses on suspected chronic obstructive pulmonary disease genes: a summa?ry of 20 years' research显示文摘SmolonskaJ Wijmenga C Postma DS 2009AmJ Respir Crit Care Med2009,180,7:1
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