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180篇 您的检索式:作者名="Wilson MD"
    题名 作者 年代 出处 被引量
1世界各地动脉粥样硬化血栓形成门诊患者心血管危险因素的流行及诊治情况显示文摘背景:动脉粥样硬化血栓形成是导致心血管疾病和死亡的主要原因。至今,尚无国际数据库阐述动脉粥样硬化血栓形成患者动脉硬化危险因素的特征和治疗强度。 目的:确定动脉粥样硬化危险因素的发生及治疗在世界许多国家是否具有可比性。设计、地点及参试者:“降低动脉粥样硬化血栓形成保持健康研究”(Reduction of Atherothrombosis for Continued Health,REACH)搜集了动脉粥样硬化危险因素及治疗情况的数据。从2003年到2004年,44个国家、5473位内科从业医师总共发现67888例年龄≥45岁的动脉病患者(冠心病[coronaryartery disease,CAD],n=40258;脑血管病,n=18843;周围动脉病,n=8273)或≥3个动脉粥样硬化血栓形成危险因素(n=12389)。主要观测指标:动脉粥样硬化危险因素的基线发生率、药物应用情况及危险因素控制程度。结果:全世界动脉粥样硬化血栓形成患者具有相似的危险因素,即高血压(81.8%)、高胆固醇血症(72.4%)以及糖尿病(44.3%)的比例高。超重(39.8%)、肥胖(26.6%)以及病态肥胖(3.6%)的发生率在大部分地区相似,但是以北美最高(超重:37.1%,肥胖:36.5%,病态肥胖:5.8%;与其他地区比较P〈0.001)。患者采用他汀(总共69.4%;范围:从脑血管病的56.4%到CAD的76.2%)、抗血小板治疗(总共78.6%;范围:从≥3个危险因素的53.9%到CAD的85.6%)及其他循证(降低危险)普遍不足。确诊有血管病的患者在吸烟者为数可观(14.4%)。高血压病治疗不足(基线50.0%血压升高)、高血糖诊断不足(4.9%)以及空腹血糖受损(其中36.5%不知已有糖尿病)均很常见。在有症状的动脉粥样硬化血栓形成患者中,15.9%是有症状的多血管疾病患者。 结论:这项当代大型国际数据库研究显示,在世界许多地区典型心血管危险因素的发生是一致且常见的,但是大多治疗不足、控制不得力。Deepak L. Bhatt, MD P. Gabriel Steg, MD E. Magnus Ohman, MD Alan T. Hirsch, MD Yasuo Ikeda, MD Jean-Louis Mas, MD Shinya Goto, MD Chlau-Suong Liau, MD, PhD Alain J. Richard, MD, PhD Joachim Roether, MD Peter W. F. Wilson, MD 徐成斌(译) 2007美国医学会杂志(中文版)2007,26,1:5
2ERCC1:a comparative genomic perspective显示文摘Wilson MD Ruttan CC Koop BF 2001Environ Mol Mutagen2001,38,23:1
3Suppression of allergic airway inflammation by helminth-induced regulatory T cells 显示文摘Wilson MS Taylor MD Balic A 2005Exp Med2005,202,9:1
4Apoptosis in the heart显示文摘Wilson S Colucci MD 1996The New England Journal of Medicine1996,335,16:1
5Endothelium-dependent vasodilation of cerebral arteries is altered with simulated microgravity through nitric oxide synthase and EDHF mechanisms显示文摘Prisby RD Wilkerson K Sokoya EM Bryan RM Wilson E Delp MD 2006Appl Physiol2006,,:1
6Imaging of primary chondrosarcoma:radiologic-pathologic correlation显示文摘 Walker EA Wilson AF 2003Radiographics2003,23,5:1
7From the archives of the AFIP: imaging of primary chondrosarcoma: radiolgic - pathologic cor - relation 显示文摘Murphey MD Walker EA Wilson AJ 2003Radiographics2003,23,5:1
8ERCC1 : a corn parative genomic perspective显示文摘Wilson MD Ruttan CC Koop BF 2001Environ Mol Mutagen2001,38,23:1
9Fat injection to correctcontour deformities in the reconstructed breast 显示文摘Spear SL Wilson HB Lockwood MD 2005Plast Reconstr Surg2005,116,5:1
10Macrophage ABCAIreduces MyD88-dependent Toll-like receptor trafficking to lipidrafts by reduction of lipid raft cholesterol 显示文摘Zhu X Owen JS Wilson MD 2010J Lipid Res2010,51,:1
11Cervical preparation for surgicalabortion between 12 and 18 weeks of gestation using vaginal misopros-tol and Dilapan-S显示文摘Wilson LC Meyn LA Creinin MD 2011Contraception2011,83,6:1
12Functional outcome following surgical treatment of intra-artieular distal humeral fractures through a posterior ap proach 显示文摘McKee MD Wilson TL Winston L 2000J Bone Joint Surg (Am)2000,82,12:1
13Glucocorticoid-induced formation of cross-linked actin networks in cultured human trabecular meshwork cells显示文摘Clark AF Wilson K McCartney MD Miggans ST Kunkle M Howe W 0,,01:1
14ERCCI: A comparative genomic perspective 显示文摘Wilson MD Ruttan CC Koop BF 2001Environ Mol Mutagen2001,38,23:1
15From the archives of the AFIP: imaging of primary chondrsarcoma: Radiologi-pathologic corre- lation 显示文摘Murphey MD Wilson A J 2003Radiographics2003,23,5:1
16Secreted proteins from rat Sertol i cel s显示文摘Wilson RM Griswold MD 0,,01:1
17Functional out- come following surgical treatment of intra-articular distal humeral fractures through a posterior approach 显示文摘McKee MD Wilson TL Winston L 2000J Bone Joint Surg(Am)2000,82,12:1
18From the archives of the AFIP:imaging of primary chondrosarcoma:radiologic pathologic correlation显示文摘Murphey MD Walker EA Wilson AJ 2003Radiographics2003,23,5:1
19Fat injection to correct contourdeformities in the reconstructed breast 显示文摘Spear SL Wilson HB Lockwood MD 2005Plast Reconstr Surg2005,116,5:1
20A molecular epidemiological study of sequential oral isolates of Candida albicans from terminally ill patients显示文摘Wilson MJ Williams DW Forbes MD 2001Oral Pathol Med2001,30,4:1
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