|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Pancreatic cancer and its stroma: A conspiracy theory显示文摘Pancreatic cancer is characterised by a prominent desmoplastic/stromal reaction that has received little attention until recent times. Given that treatments focusing on pancreatic cancer cells alone have failed to significantly improve patient outcome over many decades, research efforts have now moved to understanding the pathophysiology of the stromal reaction and its role in cancer progression. In this regard, our Group was the first to identify the cells(pancreatic stellate cells, PSCs) that produced the collagenous stroma of pancreatic cancer and to demonstrate that these cells interacted closely with cancer cells to facilitate local tumour growth and distant metastasis. Evidence is accumulating to indicate that stromal PSCs may also mediate angiogenesis, immune evasion and the well known resistance of pancreatic cancer to chemotherapy and radiotherapy. This review will summarise current knowledge regarding the critical role of pancreatic stellate cells and the stroma in pancreatic cancer biologyand the therapeutic approaches being developed to target the stroma in a bid to improve the outcome of this devastating disease. | Zhihong Xu Srinivasa P Pothula Jeremy S Wilson Minoti V Apte | 2014 | World Journal of Gastroenterology2014，20，32： | 10 |
| 2 | 具有低动脉粥样硬化风险特征的专业耐力运动员的亚临床冠状动脉疾病发病率显示文摘研究表明,具有冠状动脉疾病(coronary artery disease,CAD)危险因素的中老年(健将)运动员比久坐个体冠状动脉钙化(coronary artery calcium,CAC)评分更高。尚没有研究评估具有低动脉粥样硬化风险特征的专业运动员的CAD患病率。 | 刘莉 叶鹏 Merghani A Maestrini V Rosmini S Cox AT Dhutia H Bastiaenen R David S Yeo TJ Narain R Malhotra A Papadakis M Wilson MG Tome M AlFakih K Moon JC Sharma S | 2017 | 中华高血压杂志2017，25，6： | 8 |
| 3 | 金龙鱼(Scleropages:Osteoglossomorpha)化石的首次发现(英文)显示文摘金龙鱼化石的鳞片和骨骼碎片在过去时有报道,但鉴定并非十分可靠,因为在骨舌鱼科鱼类中这些鳞片和骨骼十分相似。首次记述了保存完美的金龙鱼化石,标本产于湖南湘乡下湾铺组和湖北松滋洋溪组,确立为骨舌鱼科金龙鱼属一新种:中华金龙鱼Scleropages sinensis sp.nov.。新种与现生金龙鱼(Scleropages)在头部骨骼、尾骨骼、各鳍的形状和位置以及具有网状鳞片等方面极为相似,因而归入该属。然而,新种在以下特征上不同于金龙鱼的现生种:鼻骨无纹饰,鼻骨上的感觉管显露于沟内,感觉管联合不经过顶骨,翼耳骨侧向加厚,眶前骨上的感觉孔大,眼眶后的眶下骨不完全覆盖前鳃盖骨上支,其宽高比例为0.75而非现生种的1–1.2,前鳃盖骨后下角变尖,鳃盖骨后下缘凹形、下端变尖,匙骨背突长大,脊椎46–48,椎体横突短小,胸鳍十分长大,上下两端的尾鳍条和内部鳍条等长。亚洲的现生种发现于各种河流和小溪中,比较喜欢水草茂盛的静水环境,一般游弋于表层水中,以鱼虾、昆虫等为食,新种中华金龙鱼也应该有相似的生长环境和食性。新种似具有性二形性,雄鱼体形略纤细,头部略大,口裂更深。中华金龙鱼化石的发现,说明金龙鱼属(Scleropages)和骨舌鱼属(Osteoglossum)在早始新世以前就已经分化,这对解释骨舌鱼类的跨洋分布具有十分重要的意义。 | 张江永 Mark V H WILSON | 2017 | 古脊椎动物学报2017，55，1： | 3 |
| 4 | Effects of three pharmaceutical and personal care products on natural freshwater algal assemblages显示文摘 | Wilson B A Smith V H Frank D J R | 2003 | Environ Sci Technol2003，37，9： | 1 |
| 5 | Death receptor signal transducers : nodes of coordination in immune signaling net-works 显示文摘 | Wilson NS Dixit V Ashkenazi A | 2009 | Nat Immunol2009，10，： | 1 |
| 6 | A hypervariable minisatellite region in human DNA显示文摘 | Jeffreys A J Wilson V Thein SL | 1985 | Nature1985，314，： | 1 |
| 7 | On the self-similar nature of Ethernet traffic显示文摘 | Leland W E Taqqu M S Willinger W and Wilson D V | 1994 | IEEE/ACM Transactions on Networking1994，2，1： | 1 |
| 8 | An algorithmic description of XCA 显示文摘 | BUTZ M V WILSON S W | 2002 | Soft Computing2002，6，34： | 1 |
| 9 | Bayesian networks for muhi- level system reliability 显示文摘 | WILSON A G HUZURBAZAR A V | 2007 | Reliability Engineering and System Safety2007，92，10： | 1 |
| 10 | Effects of three pharmaceutical and personal care products on natural freshwater algal assemblages显示文摘 | WILSON B A SMITH V H DENOYELLES F | 2003 | Environ Sci Technol2003，37，9： | 1 |
| 11 | Using experiments to inform the privatization/dercgulation movement in electricity显示文摘 | RASSENTI S J SMITH V L WILSON B J | 2002 | Cato Journal2002，21，3： | 1 |
| 12 | Detection and cellular localization of heperin-binding epidermal growth factor-like growth factor mRNA and protein in human atherosclerotic tissue显示文摘 | Reape T J Wilson V J Kanczler J M | 1997 | J Mol Cell Cardiol1997，29，6： | 1 |
| 13 | The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease显示文摘 | Velaga MR Wilson V Jennings CE | 2004 | J Clin Endocrinol Metab2004，89，11： | 1 |
| 14 | Proxi- mal femoral fractures: A biomechanical study to compare intramedullary and extramedullary fixation显示文摘 | Crurtis M J Jinnah RH Wilson V | 2004 | Injury2004，25，1： | 1 |
| 15 | DNA methylation decreases in aging but not in immortal cells显示文摘 | Wilson V L Jones P A | 1988 | Science1988，220，： | 1 |
| 16 | Heart to heart: a program for children on a cardiac ward显示文摘 | SCARFE G REDSHAW S WILSON V | 2012 | Br J Nurs2012，21，2： | 1 |
| 17 | The complete sequence of the mitochondrial genome of the crustacean Penaeus monodon:are malacostracan crustaceans more closely related to insects than to branchiopods?显示文摘 | Wilson K Cahill V Ballment E | 2000 | Molecular Biology and Evolution2000，17，6： | 1 |
| 18 | Cumulative effects of in utero administration of mixtures of 'antiandrogens' on male rat reproductive development 显示文摘 | RIDER C V WILSON V S HOWDESHELL K L | 2009 | Toxicol Pathol2009，37，： | 1 |
| 19 | Progressive mierovMcular injuryin liver and coloreetal livennetastases following laser induced focal hyperthermia therapy显示文摘 | Nildarjam M Muralidharan V Wilson C | 2005 | Lasera Surg Med2005，37，1： | 1 |
| 20 | Estimation of the surface accessible inclusion sites of β - cyclodextrin based copolymer materials 显示文摘 | MOHAMED M H WILSON L D HEADLEY J V | 2010 | Carbohydrate Polymers2010，80，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员