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| 1 | Single-center study comparing computed tomography colonography with conventional colonoscopy显示文摘AIM:To compare the results from computed tomography (CT) colonography with conventional colonoscopy in symptomatic patients referred for colonoscopy. METHODS: The study included 227 adult outpatients, mean age 60 years, with appropriate indications for colonoscopy. CT colonography and colonoscopy were performed on the same day in a metropolitan teaching hospital. Colonoscopists were initially blinded to the results of CT colonography but there was segmental unblinding during the procedure. The primary outcome measures were the sensitivity and specificity of CT colonography for the identification of polyps seen at colonoscopy (i.e. analysis by polyp). Secondary outcome measures included an analysis by patient, extracolonic findings at CT colonography, adverse events with both procedures and patient acceptance and preference. RESULTS: Twenty-five patients (11%) were excluded from the analysis because of incomplete colonoscopy or poor bowel preparation that affected either CT colonography, colonoscopy or both procedures. Polyps and masses (usually cancers) were detected at colonoscopy and CT colonography in 35% and 42% of patients, respectively. Of nine patients with a finaldiagnosis of cancer, eight (89%) were identified by CT colonography as masses (5) or polyps (3). For polyps analyzed according to polyp, the overall sensitivity of CT colonography was 50% (95% CI, 39%-61%) but this increased to 71% (95% CI, 52%-85%) for polyps ≥ 6 mm in size. Similarly, specificity for all polyps was 48% (95% CI, 39%-58%) increasing to 67% (95% CI, 56%-76%) for polyps ≥ 6 mm. Adverse events were uncommon but included one colonic perforation at colonoscopy. Patient acceptance was high for both procedures but preference favoured CT colonography. CONCLUSION: Although CT colonography was more sensitive in this study than in some previous studies, the procedure is not yet sensitive enough for widespread application in symptomatic patients. | Ian C Roberts-Thomson Graeme R Tucker Peter J Hewett Peter Cheung Ruben A Sebben EE Win Khoo Julie D Marker Wayne K Clapton | 2008 | World Journal of Gastroenterology2008，14，3： | 4 |
| 2 | Hepatitis C virus therapy with peg-interferon and ribavirin in Myanmar: A resource-constrained country显示文摘AIM To investigate peg-interferon(peg-IFN) and ribavirin(RBV) therapy in Myanmar and to predict sustained virologic response(SVR).METHODS This single-center, open-label, study was conducted in Myanmar between 2009 and 2014. A total of 288 patients infected with HCV genotypes 1, 2, 3 and 6 were treated with peg-IFN alpha-2a(180 μg/wk) or alpha-2b(50 to 100 μg as a weight-based dose) and RBV as a weight-based dose(15 mg/kg/d). Treatment duration was 48 wk for genotypes 1 and 6, 24 wk for genotype 2, and 24 or 48 wk for genotype 3 based on rapid virologic response(RVR). Those co-infected with hepatitis B received 48 wk of therapy.RESULTS Overall, SVR was achieved for 82% of patients and the therapy was well tolerated. All patients achieved SVR at equivalent rates regardless of HCV genotype(P = 0.314). Low fibrosis scores(P < 0.001), high baseline albumin levels(P = 0.028) and low baseline viral loads(P = 0.029) all independently predicted SVR. On the other hand, IL-28 B TT and CC genotypes were not found to significantly predict SVR(P = 0.634; P = 0.618). Among those who completed treatment, the occurrence of RVR showed a > 96% positive predictive value for achieving SVR. Treatment duration did not significantly impact the likelihood of achieving SVR for patients infected with genotype 3 HCV(P = 0.371). The most common adverse events were fatigue(71%) and poor appetite(60%). Among patients with genotype 3 HCV, more patients in the 48-wk treatment group required erythropoietin than in the 24-wk treatment group(61.1% vs 49.2%).CONCLUSION SVR rates were high with peg-IFN and RBV therapy in Myanmar. Fibrosis scores, baseline albumin, HCV RNA levels and RVR independently predicted SVR. | Naomi Khaing Than Hlaing Debolina Banerjee Robert Mitrani Soe Htet Arker Kyaw San Win Nyan Lin Tun Zaw Thant Khin Maung Win K Rajender Reddy | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 3 | Comparison of two different approaches for the application of the mini nutritional assessment in nursing homes: resident interviews versus assessment by nurs- ing staff显示文摘 | Kaiser R Winning K Uter W | 2009 | J Nutr Health Aging2009，13，10： | 1 |
| 4 | In vitro and in vivo studies on vitamin E TPGS-emulsified poly ( D, L-lactic-co-gly- colic acid )nanoparticles for paclitaxel formulation 显示文摘 | WIN K Y FENG S S | 2006 | B iomaterials2006，27，10： | 1 |
| 5 | Shape of A hypemuclei inthe (fi, y) deformation plane显示文摘 | Win M T Hagino K Koike T | 2011 | Physical Review C2011，83，01： | 1 |
| 6 | Wide distribution of Plasmodium ovale in Myanmar 显示文摘 | Win TY Lin K Mizuno S | 2002 | Trop Med Int Health2002，7，3： | 1 |
| 7 | Nanoparticles of biode- gradable polymers for clinical administration of paclitaxel 显示文摘 | Feng S S Mu L Win K Y | 2004 | Curr Med Chem2004，11，4： | 1 |
| 8 | Effects of cinnamon extract, chitosan coating, hot water treatment and their combinations on crown rot disease and quality of banana fruit显示文摘 | Win N K K Jitareerat P Kanlayanarat S | 2007 | Postharvest Biol Tec2007，45，： | 1 |
| 9 | Wide distribution of Plasmodium ovale in Myanmar显示文摘 | Win TT Lin K Mizuno S | 2002 | Trop Med Int HEALTH2002，7，3： | 1 |
| 10 | Identification of new parvovirus DNA sequence in swine sera from Myanmar 显示文摘 | Hijikata M Abe K Win KM | 2001 | Jpn J Infect Dis2001，54，6： | 1 |
| 11 | Clinical outcomes and stent thrombosis following off-label use of drug-eluting stents显示文摘 | Win HK Caldera AE Maresh K | 2007 | JAMA2007，297，18： | 1 |
| 12 | Depressive symptoms, physical inactivity and risk of cardiovascular mortality in older a- dults : the cardiovascular health study 显示文摘 | Win S Parakh K Eze-Nliam CM | 2011 | Heart2011，97，6： | 1 |
| 13 | Induction of protective immunity against Japanese encephalitis in mice by immunization with a plasmid encoding JE virus premembrane and envelope genes显示文摘 | Konishi E Yamaoka M Win K S | 1988 | J Virology1988，72，： | 1 |
| 14 | Elfect of 1-MCP on storage life,quality and antioxidant enzyme activities of broccoli显示文摘 | Wang Q M Win K | 2002 | Journal of Zhejiang Univ(Agric & Life Sci)2002，28，5： | 1 |
| 15 | Wide distribution of Pla显示文摘 | Win TT Kin K Mizuno S | 2002 | Trop Med Int Health2002，7，3： | 1 |
| 16 | Biologically Active Allkylatedcoumarins from Kayeaassamica显示文摘 | Lee K H Chai H B Tamez P A Pezzuto J M Cordell G A Win K K TinWa M | 2003 | Phyto Chemistry2003，64，2： | 1 |
| 17 | The feasibility conditions for interference alignment in MIMO networks显示文摘 | RUAN L LAU V K N WIN M Z | 2013 | IEEE Transactions on Signal Processing2013，61，58： | 1 |
| 18 | Identification of new parvovirus DNA sequence in swine sera from Myanmar显示文摘 | HIJIKATA M ABE K WIN K M | 2001 | Jpn J Infect Dis2001，54，6： | 1 |
| 19 | Rare influenza A(H3N2)variants with reduced sensitivity to antiviral drugs显示文摘 | Dapat C Suzuki Y Saito R Kyaw Y Myint Y Y Lin N Oo H N Oo K Y Win N Naito M Hasegawa G Dapat I C Zaraket H Baranovich T Nishikawa M Saito T Suzuki H | 2010 | Emerg Infect Dis2010，16，3： | 1 |
| 20 | Evolution of secondary metabolites from an eco- logical and molecolar phylogenetic perspective 显示文摘 | Win K M | 2003 | Phyto- chemistry2003，64，319199561： | 1 |
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