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| 1 | Prognostic factors and predictors of postoperative adjuvant transcatheter arterial chemoembolization benefit in patients with resected hepatocellular carcinoma显示文摘BACKGROUND Postoperative adjuvant transcatheter arterial chemoembolization (PA-TACE) has improved overall survival (OS) in patients with hepatocellular carcinoma (HCC).However,the prognostic and predictive factors remain unclear.AIM To assess the prognostic factors and the predictors of PA-TACE benefit for OS in patients with resected HCC.METHODS Univariate and multivariate analyses were performed to identify the potential prognostic factors for OS.In order to assess the predictive factors of PA-TACE benefit,the interaction variables between treatments for each subgroup were evaluated using the Cox proportional hazards regression model.RESULTS A total of 378 patients (PA-TACE vs surgery alone,189:189) from three centerswere included after a propensity-score 1:1 matching analysis.Compared to the group receiving surgery alone,PA-TACE prolonged the OS rate in patients with resected HCC (P <0.001).The Barcelona Clinic Liver Cancer system and ferritinto-hemoglobin ratio (FHR) were used as the prognostic factors for OS in both groups.Age (P=0.023) and microscopic vascular invasion (MVI)(P=0.002) were also identified in the PA-TACE group,while gender (P=0.027),hepatitis B virus(P=0.034) and albumin-bilirubin grade (P=0.027) were also selected in the surgery alone group.In addition,PA-TACE resulted in longer OS than surgery alone across subgroups [all hazard ratios (PA-TACE-to-surgery alone)<1].Notably,a significantly prolonged OS following PA-TACE was observed in patients with high FHR (P=0.038) and without MVI (P=0.048).CONCLUSION FHR and Barcelona Clinic Liver Cancer stages were regarded as prognostic factors for OS.Moreover,high FHR and the absence of MVI were important predictive factors,which can be used to assist clinicians in selecting which patients could achieve a better OS with PA-TACE. | Ming-Yu Chen Sarun Juengpanich Jia-Hao Hu Win Topatana Jia-Sheng Cao Chen-Hao Tong Jian Lin Xiu-Jun Cai | 2020 | World Journal of Gastroenterology2020，26，10： | 4 |
| 2 | Hepatitis C virus therapy with peg-interferon and ribavirin in Myanmar: A resource-constrained country显示文摘AIM To investigate peg-interferon(peg-IFN) and ribavirin(RBV) therapy in Myanmar and to predict sustained virologic response(SVR).METHODS This single-center, open-label, study was conducted in Myanmar between 2009 and 2014. A total of 288 patients infected with HCV genotypes 1, 2, 3 and 6 were treated with peg-IFN alpha-2a(180 μg/wk) or alpha-2b(50 to 100 μg as a weight-based dose) and RBV as a weight-based dose(15 mg/kg/d). Treatment duration was 48 wk for genotypes 1 and 6, 24 wk for genotype 2, and 24 or 48 wk for genotype 3 based on rapid virologic response(RVR). Those co-infected with hepatitis B received 48 wk of therapy.RESULTS Overall, SVR was achieved for 82% of patients and the therapy was well tolerated. All patients achieved SVR at equivalent rates regardless of HCV genotype(P = 0.314). Low fibrosis scores(P < 0.001), high baseline albumin levels(P = 0.028) and low baseline viral loads(P = 0.029) all independently predicted SVR. On the other hand, IL-28 B TT and CC genotypes were not found to significantly predict SVR(P = 0.634; P = 0.618). Among those who completed treatment, the occurrence of RVR showed a > 96% positive predictive value for achieving SVR. Treatment duration did not significantly impact the likelihood of achieving SVR for patients infected with genotype 3 HCV(P = 0.371). The most common adverse events were fatigue(71%) and poor appetite(60%). Among patients with genotype 3 HCV, more patients in the 48-wk treatment group required erythropoietin than in the 24-wk treatment group(61.1% vs 49.2%).CONCLUSION SVR rates were high with peg-IFN and RBV therapy in Myanmar. Fibrosis scores, baseline albumin, HCV RNA levels and RVR independently predicted SVR. | Naomi Khaing Than Hlaing Debolina Banerjee Robert Mitrani Soe Htet Arker Kyaw San Win Nyan Lin Tun Zaw Thant Khin Maung Win K Rajender Reddy | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 3 | QSAR analysis of substituted bis显示文摘 | LIN Li WIN Wei-qi JIANG Jian-hui | 2005 | Eur J Pharm Sci2005，25，： | 1 |
| 4 | Wide distribution of Plasmodium ovale in Myanmar 显示文摘 | Win TY Lin K Mizuno S | 2002 | Trop Med Int Health2002，7，3： | 1 |
| 5 | Wide distribution of Plasmodium ovale in Myanmar显示文摘 | Win TT Lin K Mizuno S | 2002 | Trop Med Int HEALTH2002，7，3： | 1 |
| 6 | Industrial Business Cycle Linkages Between Taiwan and The U nited States:Evidence from the IT industry显示文摘 | Win Lin Chou | 2007 | Journal of Asian Economics2007，18，： | 1 |
| 7 | Rare influenza A(H3N2)variants with reduced sensitivity to antiviral drugs显示文摘 | Dapat C Suzuki Y Saito R Kyaw Y Myint Y Y Lin N Oo H N Oo K Y Win N Naito M Hasegawa G Dapat I C Zaraket H Baranovich T Nishikawa M Saito T Suzuki H | 2010 | Emerg Infect Dis2010，16，3： | 1 |
| 8 | Wide distribution of Plasmodium ovale in Myanmar显示文摘 | Win TT Lin K Mizuno S | 2002 | Trop Med Int HEALTH2002，7，3： | 1 |
| 9 | Synthesis and mesomorphic properties of Schiff base esters possessing terminal chloro substituent显示文摘A homologous series of Schiff base esters, 4-chlorobenzylidene-4'-n-alkanoyloxyanilines, containing even number of carbons at the end groups of the molecules (Cn-1H2n-1COO-, n = 4,6,8,10,12,14,16) were synthesized. The mesomorphic properties were investigated by differential scanning calorimetry (DSC) and polarizing optical microscopy (POM). It was found that the end groups of the molecules had an effect on the mesomorphic properties. n-Butanoyloxy was found non-mesogenic, whilst n-hexanoyloxy exhibited monotropic smectic phase. The higher members in this homologous series were enantiotropic smectogens. | Sie Tiong Ha Lay Khoon Ong Siew Ling Lee Hong Cheu Lin Yip Foo Win Siew Teng Ong | 2010 | Chinese Chemical Letters2010，21，6： | 1 |
| 10 | Economic Growth and International Trade: The Case of Hong Kong, 显示文摘 | Chou Win Lin Kar - yiu Wong | | presented at the Conference on Dynamics Economic Growth and International Trade organised by the Copenhagen Business School and the Department of Economics Chinese University of Hong Kong in Hong Kong July0，2223，： | 1 |
| 11 | Wide distribution of Plasmodium ovale in Myanmar 显示文摘 | Win TY Lin K Mizuno S et cd | 2002 | Trop Med Int Health2002，7，3： | 1 |
| 12 | Wide distribution of Hasmodi- um ovale in Myanmar 显示文摘 | Win TI' Lin K Mizuno S | 2002 | Trop Med lnt Health2002，7，3： | 1 |
| 13 | Wide distribution of Plas- modium ovale in Myanmar 显示文摘 | Win TT Lin K Mizuno S | 2002 | Trop Med Int Health2002，7，3： | 1 |
| 14 | Wide distribution of Plasmodium ovale in Myanmar显示文摘 | Win TT Lin K Mizuno S | 2002 | Trop Med Int Health2002，7，3： | 1 |
| 15 | Wide distribution of Plasmodium ovale in Myanmar显示文摘 | Win TT Lin K Mizuno S | | 0，，03： | 1 |
| 16 | EIGENPROBLEM OF SUBSTRUCTURE CHAIN AND THE EXPANSION SOLUTION显示文摘In this paper,a new method for dealing with substructure chain is presented.Here,asubstructure chain means a structure consisting of a number of identical substructures connected in series.Thismethod is parallel to the expansion method in the structural analysis according to the transverse section.Themethod of shift invariance and that of initial parameter and transfer matrix,their mutual-relation and com-bined use,as well as the analysis of the eigenproblem on the transverse section,and the expansion methodbased on the eigenvectors are described in this paper. | Zhong Wanxie Lin Jiahao Qiu Chunhang (Dalian University of Technology Winning Software System Engineering Ltd.) | 1991 | Acta Mechanica Sinica1991，7，2： | 1 |
| 17 | Wide distribution of Plasmodium ovale in Mvanmar显示文摘 | Win TT Lin K Mizuno S | 2002 | Troo Med Int Heahv2002，7，3： | 1 |
| 18 | New mesogenic Schiff base esters comprising benzothiazole moiety:Synthesis and mesomorphic properties显示文摘Schiff 基础酉旨的一个相应系列, 6-methoxy-2-(2-hydroxy-4-alkanoyloxybenzylidenamino ) benzothiazoles,作为核心包括 benzothiazole 一半被综合。这个系列的所有成员展出了一个二形互变的 nematic 阶段。与侧面的氢氧根和终端 methoxyl 组一起的 azomethine 连接被发现在具有由中胚叶发达的性质上施加效果。 | Sie Tiong Ha Teck Ming Koh Guan Yeow Yeap Hong Cheu Lin Jun Kit Beh Yip Foo Win Peng Lim Boey | 2009 | Chinese Chemical Letters2009，20，9： | 0 |
| 19 | Observed characteristics of flow,water mass,and turbulent mixing in the Preparis Channel显示文摘Preparis Channel is the very important exchange path of energy and materials between the northern Bay of Bengal and Andaman Sea(AS).A set of hydrographic measurements,a microstructure profiler,and a deep mooring were used to determine the characteristics of water masses,turbulent mixing,and flows in the Preparis Channel.The unprecedented short-term mooring data reveal that a deep current in the deep narrow passage(below 400 m)of the Preparis Channel flows toward the Bay of Bengal(BoB)with a mean along-stream velocity of 25.26 cm/s at depth of 540 m;above the deep current,there are a relatively weak current flows toward the AS with a mean along-stream velocity of 15.46 cm/s between 500 m and 520 m,and another weak current flows toward the BoB between 430 m and 500 m.Thus,a sandwiched vertical structure of deep currents(below 400 m)is present in the Preparis Channel.The volume transport below 400 m is 0.06 Sv(1 Sv=106 m^(3)/s)from the AS to the BoB.In the upper layer(shallower than 300 m),the sea water of the AS is relatively warmer and fresher than that in the BoB,indicating a strong exchange through the channel.Microstructure profiler observations reveal that the turbulent diffusivity in the upper layer of the Preparis Channel reaches O(10−4 m^(2)/s),one order larger than that in the interior of the BoB and over the continental slope of the northern AS.We speculate that energetic high-mode internal tides in the Preparis Channel contribute to elevated turbulent mixing.In addition,a local“hotspot”of turbidity is identified at the deep mooring site,at depth of about 100 m,which corresponds to the location of elevated turbulent mixing in the Preparis Channel. | Ruijie Ye Feng Zhou Xiao Ma Dingyong Zeng Feilong Lin Hongliang Li Chenggang Liu Soe Moe Lwin Hlaing Swe Win Soe Pyae Aung | 2023 | Acta Oceanologica Sinica2023，42，2： | 0 |
| 20 | The effect of pharmaceutical care in the elderly patients with type 2 diabetes mellitus显示文摘Pharmaceutical care plays a crucial role in reducing mortality and morbidities of the patients.A hospital based quasiexperimental study was conducted with elderly patients with type 2 diabetes who attended at the diabetes clinic of No.(2)Military Hospital(500-Bedded)in Myanmar from April 2013 to February 2014.The aim of this study was to evaluate the effect of pharmaceutical care in elderly patients with type 2 diabetes mellitus.A total of 52 respondents enrolled in this study.The clinical outcomes and quality of life of patients before and eight months after intervention were assessed.Pharmaceutical care program was implemented as intervention.Of the total number of respondents,52 drug related problems were identified. | Win Myat Maw Mi Mi Saw Theingi Kyaw Khin Ohnmar Kyaing Zaw Min Latt KyawZaw Lin Aung PyaePhyo | 2016 | Asian Journal of Pharmaceutical Sciences2016，11，1： | 0 |
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