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| 1 | 电动牙刷与手动牙刷对口腔卫生的效果比较显示文摘目的对电动牙刷和手动牙刷在去除菌斑、维护牙龈健康、对色素和牙结石的作用、可靠性、不良作用和成本等进行比较.方法计算机检索Cochrane口腔健康协作组临床试验资料库(截至2004年6月17日)、Cochran临床对照试验中心资料库(Cochrane图书馆2004第2期)、MEDLINE(1966~2004)、EMBASE(1980~2004第2周)和CINAHL(1982~2004第2周),并与制造商联系以获取更多资料.根据下列标准纳入随机对照试验:随机分配研究对象;参加者为手运动无障碍的普通人群;干预措施为无监督的手动或电动牙刷刷牙,至少4周;主要结局指标为试验期间菌斑和牙龈炎的变化.由6个作者独立评价并纳入研究资料.用随机效应模型进行Meta分析,用标准化均数差(SMD)及其95%CI测量效果.检查可能的异质性来源,并针对研究质量和发表偏倚进行敏感性分析.为便于讨论,将SMD转换为百分率.结果对包含3 855例研究对象的42个试验进行系统评价,结果显示,旋转振动型电动牙刷去除菌斑和减低牙龈炎的效果在短期内明显优于手动牙刷,并在3个月以上的研究中显示降低了牙龈炎指数.在1~3个月的研究中,菌斑SMD为-0.43 [95%CI (-0.72, 0.14)],牙龈炎SMD为-0.62 [95%CI (-0.90, 0.34)],Quigley Hein菌斑指数降低11%,Loe and Silness龈炎指数降低6%.在3个月以上的研究中,菌斑指数SMD为-1.29 [95%CI (-2.67, 0.08)], 龈炎指数为-0.51 [95%CI (-1.76, 0.25)],Ainamo Bay探诊出血指数降低17%.短期研究之间有异质性,敏感性分析显示当选择高质量的研究时结果是肯定的,没有证据表明有发表偏倚.采取其他设计的电动牙刷并不比手动牙刷更优.对成本、可靠性和不良作用的报道不一致,已报道的不良作用都是局限的、暂时的.结论旋转振动型电动牙刷去除牙菌斑、减少牙龈炎的效果优于手动牙刷.遵守方法学指南和更标准化的设计有益于将来的研究和Meta分析. | Robinson PG Deacon SA Deery C Heanue M Walmsley AD Worthington HV Glenny AM Shaw WC 陈娥 史宗道 | 2005 | 中国循证医学杂志2005，5，11： | 8 |
| 2 | Randomized clinical trial on enhanced recovery versus standard care following open liver resection显示文摘 | C. Jones L. Kelliher M. Dickinson A. Riga T. Worthington M. J. Scott T. Vandrevala C. H. Fry N. Karanjia N. Quiney | 2013 | Br J Surg2013，，8： | 3 |
| 3 | A randomised controlled trial of a new 2 litre polyethylene glycol solution versus sodium picosulphate + magnesium citrate solution for bowel cleansing prior to colonoscopy*显示文摘 | J. Worthington M. Thyssen G. Chapman R. Chapman M. Geraint | 2008 | Current Medical Research and Opinion?2008，，2： | 3 |
| 4 | Genetic and genomic resources for Rubus breeding:a roadmap for the future显示文摘Rubus fruits are high-value crops that are sought after by consumers for their flavor,visual appeal,and health benefits.To meet this demand,production of red and black raspberries(R.idaeus L.and R.occidentalis L.),blackberries(R.subgenus Rubus),and hybrids,such as Boysenberry and marionberry,is growing worldwide.Rubus breeding programmes are continually striving to improve flavor,texture,machine harvestability,and yield,provide pest and disease resistance,improve storage and processing properties,and optimize fruits and plants for different production and harvest systems.Breeders face numerous challenges,such as polyploidy,the lack of genetic diversity in many of the elite cultivars,and until recently,the relative shortage of genetic and genomic resources available for Rubus.This review will highlight the development of continually improving genetic maps,the identification of Quantitative Trait Loci(QTL)s controlling key traits,draft genomes for red and black raspberry,and efforts to improve gene models.The development of genetic maps and markers,the molecular characterization of wild species and germplasm,and highthroughput genotyping platforms will expedite breeding of improved cultivars.Fully sequenced genomes and accurate gene models facilitate identification of genes underlying traits of interest and enable gene editing technologies such as CRISPR/Cas9. | Toshi M.Foster Nahla V.Bassil Michael Dossett Margaret Leigh Worthington Julie Graham | 2019 | Horticulture Research2019，6，1： | 2 |
| 5 | A 10-year study of outcome following hepatic resection for colorectal liver metastases – The effect of evaluation in a multidisciplinary team setting显示文摘 | J.T. Lordan N.D. Karanjia N. Quiney W.J. Fawcett T.R. Worthington | 2008 | European Journal of Surgical Oncology2008，，3： | 2 |
| 6 | MR imaging of the knee: exanole of normal anatomy and pathology 显示文摘 | Kean DM Worthington BS Preston BJ | 1983 | Br J Radiol1983，56，： | 2 |
| 7 | A comparison of right and extended right hepatectomy with all other hepatic resections for colorectal liver metastases: A ten-year study显示文摘 | N.D. Karanjia J.T. Lordan N. Quiney W.J. Fawcett T.R. Worthington J. Remington | 2007 | European Journal of Surgical Oncology2007，，1： | 2 |
| 8 | Resolution limits in ray tomography due to wave behavior : Numerical experiments 显示文摘 | Williamson P R Worthington M H | 1993 | Geophysics1993，58，： | 1 |
| 9 | Incisal edge reattachment:indications for use and clinical technique显示文摘 | Murchison D F Burke F J Worthington R B | 1999 | Br Dent J1999，186，12： | 1 |
| 10 | Relationship quality and burden among caregivers for latestage cancer 显示文摘 | Francis L E Worthington J Kypriotakis G | 2009 | Support Care Cancer2009，18，11： | 1 |
| 11 | Some comparisons between auditory brain stem response thresholds,latencies,and the pure-tone audiogram显示文摘 | Gorga MP Worthington DW Reiland JK | 1985 | Ear and Hearing1985，6，2： | 1 |
| 12 | The association between psychological factors and oro-facial pain:a community-based study显示文摘 | Macfarlane TV Kincey J Worthington HV | | 0，，06： | 1 |
| 13 | Aripiprazole as an augmentor of selective serotonin reuptake inhibitors in depression and anxiety disorder patients 显示文摘 | Worthington JJ Kinrys G Wygant LE | 2005 | Int Clin Psychopharmacol2005，20，： | 1 |
| 14 | Controls on tropical pacific ocean productivity revealed through nutrient stress diagnostics显示文摘 | Behrenfeld M J Worthington K Sherrell R M | 2006 | Nature2006，442，： | 1 |
| 15 | Analysis of power output of piezoelectric energy-harvesting devices directly connected to a load resistor using a coupled plezoeleetric-cireuit finite element method 显示文摘 | ZHU M wORTHINGTON E NJUGUNA J | 2009 | IEEE Trans Ultrason Ferroeleetr Freq Control2009，56，7： | 1 |
| 16 | The long-- term efficacy of currently used dental implants: a review and proposed criteria of success 显示文摘 | Albrektsson T Zarb GT Worthington P | 1986 | Int J Oral Maxillofac Implant1986，11，： | 1 |
| 17 | The long-term efficacy of currently used dental implants : a review and proposed criteria of success显示文摘 | Albrektsson T Zarb G Worthington P | 1986 | Int J Oral Maxillofac Implants1986，21，1： | 1 |
| 18 | Collectivism,Forgiveness,and Social Harmony显示文摘 | Hook J N Utsey S O Worthington E L | 2009 | Counseling Psychologist2009，37，6： | 1 |
| 19 | Disk arrays: high- performance, high- reliability storage subsystems 显示文摘 | Gregory R Ganger Bruce L Worthington Robert Y | 1994 | Computer1994，27，3： | 1 |
| 20 | Design study of piezoelectric energy harvesting devices for generation of higher electrical power using a coupled piezoelectric-circuit finite element method 显示文摘 | ZHU M WORTHINGTON E TIWARI A | 2010 | IEEE Trans Ultrason Ferroelectr Freq Control2010，57，2： | 1 |
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