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| 1 | Would integrated Western and traditional Chinese medicine have more benefits for stroke rehabilitation? A systematic review and meta-analysis显示文摘Background Stroke is a major cause of death or long-term disability worldwide.Many patients with stroke receive integrative therapy consisting of Western medicine(WM)and routine rehabilitation in conjunction with Chinese medicine(CM),such as acupuncture and Chinese herbal medicine.However,there is no available evidence on the effectiveness of the combined use of WM and CM interventions in stroke rehabilitation.Aims The purpose of this meta-analysis is to evaluate the results of all individual studies to assess the combined use of CM and WM in stroke rehabilitation compared with WM only.Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines were followed.MEDLINE,EMBASE,Cochrane and China National Knowledge Infrastructure(CNKI)were searched.The included outcomes were dependency,motor function,depression and swallowing function.Subgroup analysis was performed,and publication bias was assessed using funnel plots.Summary of review 58 studies and 6339 patients were included in the meta-analysis.Subgroup analysis revealed that combined therapy comprising both acupuncture and WM had a superior effect on improving dependency and swallowing function compared with standard WM therapy alone.Potential superiority of combined therapy comprising CM and WM in improving depression compared with standard WM therapy was also found.Conclusions Our results indicate that the combined use of CM and WM could be more efficacious in stroke rehabilitation compared with the use of WM therapy alone.However,most studies were short in duration(2 to 4 weeks)and prone to different types of biases,which prevents making any conclusion regarding the long-term effects and raises concerns regarding true efficacy in context of high likelihood of Hawthorn bias.So,more randomised controlled trials with more rigorous design and longer duration of treatment and follow-up need to be conducted to compare WM alone versus WM and CM combined. | Linda LD Zhong Ya Zheng Alexander Y Lau Norman Wong Liang Yao Xingyao Wu Tengteng Shao Zhenxing Lu Huijuan Li Chun Sum Yuen Jianwen Guo Suzanne Lo Janita Chau Kam Wa Chan Bacon Fung Leung Ng Zhaoxiang Bian Edwin Chau-leung Yu | 2022 | Stroke & Vascular Neurology2022，7，1： | 7 |
| 2 | A meta-analysis of soluble suppression of tumorigenicity 2 (sST2) and clinical outcomes in pulmonary hypertension显示文摘 | King Sum Luk Christina Ip Meng-Qi GONG Sunny Hei WONG William KK Wu Mei DONG Guang-Ping LI Ka Pang Chan Yi-Mei DU Tong LIU Martin CS Wong David Shu Cheong Hui Gary Tse | 2017 | Journal of Geriatric Cardiology2017，14，12： | 5 |
| 3 | Corrosion of carbon steel influenced by anaerobic biofilm in natural seawater显示文摘 | Duan Jizhou Wu Sum Zhang Xiaodong | 2008 | Electrochimica Acta2008，54，1： | 1 |
| 4 | Comparative study of room-temperature ferromagnetism in Cu-doped Zn0 nanowires enhanced by structural inhomogeneity显示文摘 | Xing G Z Yi J B Tao J G Liu T Wong L M Zhang Z Li G P Wang S J Ding J Sum T C.Huan C H A Wu T | | 0，，18： | 1 |
| 5 | Superabsorbent Conducting Hydrogel from Poly (Acrylamide-aniline) with Thermo-Sensitiv- ity and Release Properties显示文摘 | Qw Tang JH Wu H Sum | 2007 | Carbohydrate Polymers2007，67，： | 1 |
| 6 | The early prediction of mortality in acute pancreatitis : a large population based study 显示文摘 | Wu B Johannes RS Sum K | 2008 | Gut2008，57，12： | 1 |
| 7 | Microsecond Simulations of Spontaneous Methane Hydrate Nucleation and Growth 显示文摘 | Matthew R Walsh Carolyn A Koh E Dendy Sloan Amadeu K Sum David T Wu | 2009 | Science2009，326，20： | 1 |
| 8 | Magnifying colonoscopy in differentiating neoplastic from nonneoplastic colorectal lesions显示文摘 | TUNG S Y WU C S SUM Y | 2001 | Am J Gastroenterol2001，96，9： | 1 |
| 9 | Magnifying colonoscopy in differentiating neoplastic from nonneoplastic colorectal lesions 显示文摘 | TUNG S Y WU C S SUM Y | 2001 | Am J Gastroenterol2001，96，9： | 1 |
| 10 | MicroRNA and cancer: Current status and prospective 显示文摘 | WU W SUM M ZOU G M | 2007 | International Journal of Cancer2007，120，5： | 1 |
| 11 | Comparative effects of thiopentone and propofol on respiratory resistance after tracheal intubation 显示文摘 | WU RSC WU DC SUM DCW | 1996 | Br J Anaesth1996，76，6： | 1 |
| 12 | Comparative effects of thiopentone and propofol on respiratory resistance after tracheal intubation 显示文摘 | Wu RS Wu KC Sum DC | 1996 | Br J Anaesth1996，77，6： | 1 |
| 13 | 显示文摘 | Wu N Q FuL SuM | 2004 | Nano Letters2004，4，： | 1 |
| 14 | Detection of Gene Alteration for Color Vision Defects by Polymerase Chain Reaction显示文摘According to the fact that the abnormalities of visual pigment genes were always involved in the changing of the exon 5, two oligonucleotide primers were designed to amplify the exon 5 of red pigment gene and green pigment gene. After electrophoresis of the PCR products digested with Rsal or Sau3A, the DNA fragments from the exon 5 of red pigment gene (RPG) and green pigment gene (GPG) were separated since there are different restriction endonuclease sites. On the other hand, we analyzed the exon 5 rela... | Qingjiong Zhang, Wenshu Mao, Qiaoyun Ma, Ruiping Zeng , Lezheng Wu, De-Zheng Wu, Youzhao Chen Eye Research Institute, Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences Guangzhou 510060, China.~+Department of Medical Genetics, SUMS, Guangzhou 510080, China. | 1992 | 眼科学报1992，8，1： | 0 |
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