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| 1 | Analysis of Pathological data of renal biopsy at one single center in China from 1987 to 2012显示文摘 | Zhang Xueguang Liu Shuwen Tang Li Wu Jie Chen Pu Yin Zhong Li Minxia Xie Yuansheng Cai Guangyan Wei Ribao Qiu Qiang Wang Yuanda Shi Suozhu Chen Xiangmei | 2014 | Chinese Medical Journal2014，，9： | 30 |
| 2 | Late Holocene hydroclimatic variations and possible forcing mechanisms over the eastern Central Asia显示文摘Hydroclimatic variations over the eastern Central Asia are highly sensitive to changes in hemispheric-scale atmospheric circulation systems. To fully understand the long-term variability and relationship between hydroclimate and atmospheric circulation system, we present a high-resolution lascustrine record of late Holocene hydroclimate from Lake Sayram, Central Tianshan Mountains, China, based on the total organic carbon, total nitrogen, and carbonate contents, carbon/nitrogen ratios, and grain size. Our results reveal four periods of substantially increased precipitation at the interval of 4000–3780, 3590–3210, 2800–2160, and 890–280 cal yr BP, and one period of slightly increased precipitation from 1700–1370 cal yr BP. These wetter periods broadly coincide with those identified in other records from the mid-latitude Westerlies-dominated eastern Central Asia, including the northern Tibetan Plateau. As such, a similar hydroclimatic pattern existed over this entire region during the late Holocene. Based on a close similarity of our record with reconstruction of North Atlantic Oscillation indices and solar irradiance, we propose that decreased solar irradiance and southern migration of the entire circum-North Atlantic circulation system, particularly the main pathway of the mid-latitude Westerlies, significantly influenced hydroclimate in eastern Central Asia during the late Holocene. Finally, the inferred precipitation at Lake Sayram has increased markedly over the past 100 years, although this potential future changes in hydroclimate in Central Asia need for further investigation. | Jianghu LAN Hai XU Keke YU Enguo SHENG Kangen ZHOU Tianli WANG YuANDa YE Dongna YAN Huixian WU Peng CHENG Waili ABULIEZI Liangcheng TAN | 2019 | Science China Earth Sciences2019，62，8： | 3 |
| 3 | Interference at the single-photon level based on silica photonics robust against channel disturbance显示文摘Quantum key distribution(QKD) provides a solution for communication of unconditional security. However,the quantum channel disturbance in the field severely increases the quantum bit-error rate, degrading the performance of a QKD system. Here we present a setup comprising silica planar light wave circuits(PLCs), which is robust against the channel polarization disturbance. Our PLCs are based on the asymmetric Mach–Zehnder interferometer(AMZI), integrated with a tunable power splitter and thermo-optic phase modulators. The polarization characteristics of the AMZI PLC are investigated by a novel pulse self-interfering method to determine the operation temperature of implementing polarization insensitivity. Over a 20 km fiber channel with 30 Hz polarization scrambling, our time-bin phase-encoding QKD setup is characterized with an interference fringe visibility of 98.72%. The extinction ratio for the phase states is kept between 18 and 21 d B for 6 h without active phase correction. | XIAO LI MEIZHEN REN JIASHUN ZHANG LIANGLIANG WANG WEI CHEN YUE WANG XIAOJIE YIN YUANDA WU JUNMING AN | 2021 | Photonics Research2021，9，2： | 2 |
| 4 | WO3 thin film prepared by PECVD technique and its gas sensing properties to NO2 显示文摘 | TONGMAOSONG DA GUORUI WU YUANDA | 2001 | journal of Materials Science 362001，，： | 1 |
| 5 | WO3 thin film prepared by PECVD technique and its gas sensing properties to NO2 显示文摘 | Tong Maosong Da Guorui Wu Yuanda | 2001 | Journal of Materials Science2001，36，10： | 1 |
| 6 | WO3 thin film prepared by PECVD technique and its gas sensing properties to NO2显示文摘 | Maosong Tong Guorui Dai Yuanda Wu Xiuli He Dingsan Gao | 2001 | Journal of Materials Science2001，，10： | 1 |
| 7 | Fabrication and properties of vitreous silica films prepared by flame hydroly- sis deposition 显示文摘 | Wu Yuanda Xing Hua Zhang Letian | 2004 | Materials Chemistry and Physics2004，84，： | 1 |
| 8 | WO3 thin film prepared by PECVD technique and its gas sensing properties to NO2 显示文摘 | Tong Maosong Da Guorui Wu Yuanda | 2001 | Journal of Materials Science2001，36，10： | 1 |
| 9 | WO3 thin film prepared by PECVD technique and its gas sensing properties to NO2显示文摘 | Maosong Tong Guorui Da Yuanda Wu | | 0，，： | 1 |
| 10 | Generating prototypical residential building geometry models using a new hybrid approach显示文摘Building prototyping has regularly been used in building performance analyses with statistically feasible models.The novelty of this research involves a new hybrid approach combining stratified sampling and k-means clustering to establish building geometry prototypes.The research focuses on residential buildings in Ningbo,China.Seventeen small residential districts(SRDs)containing 367 residential buildings were systemically selected for survey and data collection.The stratified sampling used building construction year as the main parameter to generate stratification.Floor numbers,shape coefficients,floor areas,and window-to-wall ratios were used as the four observations for k-means clustering.Based on this new approach,nine building geometry prototypes were identified and modelled.These statistically representative prototypes provide building geometrical information and characteristic-based evaluations for subsequent building performance analysis. | Yuanli Ma Wu Deng Jing Xie Tim Heath Yeyu Xiang Yuanda Hong | 2022 | Building Simulation2022，15，1： | 1 |
| 11 | Engineered extracellular vesicles efficiently deliver CRISPR-Cas9 ribonucleoprotein(RNP)to inhibit herpes simplex virus1 infection in vitro and in vivo显示文摘Extracellular vesicles(EVs)have recently emerged as a promising delivery platform for CRISPR/Cas9 ribonucleoproteins(RNPs),owing to their ability to minimize off-target effects and immune responses.However,enhancements are required to boost the efficiency and safety of Cas9 RNP enrichment within EVs.In response,we employed the Fc/Spa interaction system,in which the human Fc domain was fused to the intracellular domain of PTGFRN-Δ687 and anchored to the EV membrane.Simultaneously,the B domain of the Spa protein was fused to the C domain of cargos such as Cre or spCas9.Due to the robust interaction between Fc and Spa,this method enriched nearly twice the amount of cargo within the EVs.EVs loaded with spCas9 RNP targeting the HSV1 genome exhibited significant inhibition of viral replication in vitro and in vivo.Moreover,following neuron-targeting peptide RVG modification,the in vivo dosage in neural tissues substantially increased,contributing to the clearance of the HSV1 virus in neural tissues and exhibiting a lower off-target efficiency.These findings establish a robust platform for efficient EV-based SpCas9 delivery,offering potential therapeutic advantages for HSV1 infections and other neurological disorders. | Yuanda Wan Liren Li Ruilin Chen Jiajia Han Qiyun Lei Zhipeng Chen Xiaodong Tang Wenyu Wu Shuwen Liu Xingang Yao | 2024 | Acta Pharmaceutica Sinica B2024，14，3： | 0 |
| 12 | Structure and Electrical Characteristics of Zinc Oxide Thin Films Grown on Si (111) by Metal-organic Chemical Vapor Deposition显示文摘ZnO thin films were grown on Si(111) substrates by low-pressure metal-organic chemical vapor deposition.The crystal structures and electrical properties of as-grown sample were investigated by scanning electron microscopy(SEM) and conductive atomic force microscopy(C-AFM).It can be seen that with increasing growth temperature,the surface morphology of ZnO thin films changed from flake-like to cobblestones-like structure.The current maps were simultaneously recorded with the topography,which was gained by C-AFM contact mode.Conductivity for the off-axis facet planes presented on ZnO grains enhanced.Measurement results indicate that the off-axis facet planes were more electrically active than the c-plane of ZnO flakes or particles probably due to lower Schottky barrier height of the off-axis facet planes. | Yunfeng Wu Dongping Liu Naisen Yu Yuanda Liu Hongwei Liang Guotong Du | 2013 | Journal of Materials Science & Technology2013，29，9： | 0 |
| 13 | Venovenous extracorporeal membrane oxygenation for COVID-19 and influenza H1N1 associated acute respiratory distress syndrome:A comparative cohort study in China显示文摘Background Venovenous extracorporeal membrane oxygenation(VV-ECMO)has been demonstrated to be effective in treating patients with virus-induced acute respiratory distress syndrome(ARDS).However,whether the management of ECMO is different in treating H1N1 influenza and coronavirus disease 2019(COVID-19)-associated ARDS patients remains unknown.Methods This is a retrospective cohort study.We included 12 VV-ECMO-supported COVID-19 patients admitted to The First Affiliated Hospital of Guangzhou Medical University,Guangzhou Eighth People's Hospital,and Wuhan Union Hospital West Campus between January 23 and March 31,2020.We retrospectively included VV-ECMO-supported patients with COVID-19 and H1N1 influenza-associated ARDS.Clinical characteristics,respiratory mechanics including plateau pressure,driving pressure,mechanical power,ventilatory ratio(VR)and lung compliance,and outcomes were compared.Results Data from 25 patients with COVID-19(n=12)and H1N1(n=13)associated ARDS who had received ECMO support were analyzed.COVID-19 patients were older than H1N1 influenza patients(P=0.004).The partial pressure of arterial carbon dioxide(PaCO_(2))and VR before ECMO initiation were significantly higher in COVID-19 patients than in H1N1 influenza patients(P<0.001 and P=0.004,respectively).COVID-19 patients showed increased plateau and driving pressure compared with H1N1 subjects(P=0.013 and P=0.018,respectively).Patients with COVID-19 remained longer on ECMO support than did H1N1 influenza patients(P=0.015).COVID-19 patients who required ECMO support also had fewer intensive care unit and ventilator-free days than H1N1.Conclusions Compared with H1N1 influenza patients,COVID-19 patients were older and presented with increased PaCO_(2) and VR values before ECMO initiation.The differences between ARDS patients with COVID-19 and influenza on VV-ECMO detailed herein could be helpful for obtaining a better understanding of COVID-19 and for better clinical management. | Yonghao Xu Yin Xi Shuijiang Cai Yuheng Yu Sibei Chen Weijie Guan Weibo Liang Hongkai Wu Weiqun He Xilong Deng Yuanda Xu Rong Zhang Manshu Li Jieyi Pan Zhenting Liang Ya Wang Shaofeng Kong Xiaoqing Liu Zheng Lv Yimin Li | 2023 | Journal of Intensive Medicine2023，3，4： | 0 |
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