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| 1 | Vascular endothelial growth factor receptor 2(VEGFR-2) plays a key role in vasculogenic mimicry formation,neovascularization and tumor initiation by Glioma stem-like cells显示文摘Human glioblastomas(GBM)are thought to be initiated by glioma stem-like cells(GSLCs).GSLCs also participate in tumor neovascularization by transdifferentiating into vascular endothelial cells.Here,we report a critical role of GSLCs in the formation of vasculogenic mimicry(VM),which defines channels lined by tumor cells to supply nutrients to early growing tumors and | Yao X Ping Y Liu Y Chen K Yoshimura T Liu M Gong W Chen C Niu Q Guo D Zhang X Wang JM Bian X | 2013 | 中国神经肿瘤杂志2013，11，3： | 23 |
| 2 | Mechanosignaling activation of TGFβmaintains intervertebral disc homeostasis显示文摘Intervertebral disc(IVD) degeneration is the leading cause of disability with no disease-modifying treatment.IVD degeneration is associated with instable mechanical loading in the spine, but little is known about how mechanical stress regulates nucleus notochordal(NC) cells to maintain IVD homeostasis. Here we report that mechanical stress can result in excessive integrin α_vβ_6-mediated activation of transforming growth factor beta(TGFβ), decreased NC cell vacuoles, and increased matrix proteoglycan production, and results in degenerative disc disease(DDD). Knockout of TGFβ type II receptor(TβRII) or integrin α_v in the NC cells inhibited functional activity of postnatal NC cells and also resulted in DDD under mechanical loading.Administration of RGD peptide, TGFβ, and α_vβ_6-neutralizing antibodies attenuated IVD degeneration. Thus,integrin-mediated activation of TGFβ plays a critical role in mechanical signaling transduction to regulate IVD cell function and homeostasis. Manipulation of this signaling pathway may be a potential therapeutic target to modify DDD. | Qin Bian Lei Ma Amit Jain Janet L Crane Khaled Kebaish Mei Wan Zhengdong Zhang X Edward Guo Paul D Sponseller Cheryle A Seguin Lee H Riley Yongjun Wang Xu Cao | 2017 | Bone Research2017，5，1： | 9 |
| 3 | Anomalous temperature dependence of photoluminescence in MBE-grown GaInNAs/GaAs QWs 显示文摘 | Liang X G Jiang D S Bian L F | 2002 | Chinese Physics Letter2002，19，： | 2 |
| 4 | Synthesis of cyanohydron trimethylsilyl ethers of aeylferrocenes显示文摘 | Bian Z X Zhao H Y Li B G | 2003 | Poly- hedron2003，22，： | 1 |
| 5 | ComparativeStudy on Sorption/Adsorption of Radioeuropium onAlumina,Bentonite and Red Earth:Effects of pH,Ionic Strength,Fulvic Acid and Iron Oxids in RedEarth显示文摘 | Dong W M Wang X K Bian X Y | 2001 | Appl Radiat Isot2001，54，4： | 1 |
| 6 | Covalently combining carbon nanotubes with anticancer agent: preparation and antitumor activity 显示文摘 | Wu W Li R Bian X | 2009 | ACS Nano2009，3，9： | 1 |
| 7 | Cauchy Integral Formula and Plemelj Formula of Bihypermonogenic Functions in Real Clifford Analysis 显示文摘 | BIAN X ERIKSSON S L LI J | 2009 | Complex Variables and Elliptic Equations2009，54，10： | 1 |
| 8 | Genetic stability analysis of introduced Betula perdula , Betula kirghisorum , and Bettda pubescens families in saline-alkali soil of northeastern China 显示文摘 | ZHAO X Y BIAN X Y LI Z X | 2014 | Scandinavian Journal of Forest Research2014，29，7： | 1 |
| 9 | Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease显示文摘 | Yang X Chen X Bian G | 2014 | J Gene Virol2014，95，3： | 1 |
| 10 | Rufuslactone, a new antifungal sesquiterpene from the fruiting bodies of the basidiomycete Lactarius rufus显示文摘 | Luo D Q Wang F Bian X Y | 2005 | Journal of Antibiotics2005，58，： | 1 |
| 11 | Preparation and properties of rare earth oxide/polyimide hybrids显示文摘 | BIAN L J QIAN X F YIN J | 2002 | Polymer Testing2002，21，： | 1 |
| 12 | The expression of functional chemokine receptor CXCR4 is associated with the metastatic potential of human nasopharyngeal carcinoma显示文摘 | Deng X Bian X | 2005 | Clin Cancer Res2005，11，： | 1 |
| 13 | Dicofol application resulted in high DDTs residue in cotton fields from northern Jiangsu province, China显示文摘 | Yang X L Wang S S Bian Y R | 2008 | J Hazard Mater2008，150，1： | 1 |
| 14 | Peptide hormone ghrelin enhances neuro?nal excitability by inhibition of Kv7IKCNQ channels显示文摘 | Shi L Bian X Qu Z | 2013 | Nat Com?mun2013，54，： | 1 |
| 15 | Density functional theory calculations and molecular dynamics simulations of the adsorption of biomolecules on graphene surfaces 显示文摘 | Qin W Li X Bian W W Fan X J Qi J Y | 2010 | Biomaterials2010，31，5： | 1 |
| 16 | Stem cells for reprogramming:could hUMSCs be a better choice显示文摘 | Duya P Bian Y Chu X | | 0，，03： | 1 |
| 17 | 查看详情显示文摘 | Bian J Xiao M Wang S J Lu Y X Meng Y Z | | 0，，： | 1 |
| 18 | Effects of moderate exercise over different phases on age-related physiological dysfunction in testes of SAMP8 mice显示文摘 | ZHAO X BIAN Y SUN Y | 2013 | Exp Geronto12013，48，9： | 1 |
| 19 | Shear strength and water resistance of modified soy protein adhesives显示文摘 | SUN X Z BIAN K | 1999 | J Am Oil Chem Soc1999，76，8： | 1 |
| 20 | pH-dependent Cu(II) coordination polymers with tetrazole-1-acetic acid:synthesis,crystal structures,EPR and magnetic properties显示文摘 | Yu Q Zhang X Q Bian H D | 2008 | Crystal Growth and Design2008，8，4： | 1 |
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