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| 1 | Effects of Saccharomycesboulardiion fecal short-chain fatty acids and microflora in patients on long-term total enteral nutrition显示文摘AIM: To assess the effects of Sb on fecal flora and shortchain fatty acids (SCFA) in patients on long-term TEN.METHODS: Ten patients (3 females, 7 males, 59±5.5 years),on TEN for a median of 13 mo (1-125), and 15 healthy volunteers (4 females, 11 males, 32±2.0 years) received Sb (0.5 g bid PO) for 6 d. Two stool samples were taken before, on the last 2 d and 9-10 d after treatment, for SCFA measurement and for culture and bacterial identification.Values (mean±SE) were compared using sign tests and ANOVA.RESULTS: Fecal butyrate levels were lower in patients(10.1±2.9 mmol/kg) than in controls (19.2±3.9, P= 0.02).Treatment with Sb increased total fecal SCFA levels in patients (150.2±27.2 vs 107.5±18.2 mmol/kg, P = 0.02)but not in controls (129.0±28.6 vs 113.0±15.2 mmol/kg,NS). At the end of treatment with Sb, patients had higher fecal butyrate (16.0±4.4 vs 10.1 [2.9] mmol/kg, P = 0.004).Total SCFAs remained high 9 d after treatment was discontinued. Before the treatment, the anaerobe to aerobe ratio was lower in patients compared to controls (2.4±2.3 vs69.8±1.8, P = 0.003). There were no significant changes in the fecal flora of TEN patients.CONCLUSION: Sb-induced increase of fecal SCFA concentrations (especially butyrate) may explain the preventive effects of this yeast on TEN-induced diarrhea. | Stéphane M Schneider Fernand Girard-Pipau Jér(o|^)me Filippi Xavier Hébuterne Dominique Moyse Gustavo Calle Hinojosa Anne Pompei Patrick Rampal | 2005 | World Journal of Gastroenterology2005，11，39： | 26 |
| 2 | Mobilization of hematopoietic progenitor cells in patients with liver cirrhosis显示文摘AIM:To test the hypothesis that liver cirrhosis is associated with mobilization of hematopoietic progenitor cells. METHODS:Peripheral blood samples from 72 patients with liver cirrhosis of varying etiology were analyzed by flow cytometry.Identified progenitor cell subsets were immunoselected and used for functional assays in vitro. Plasma levels of stromal cell-derived factor-1(SDF-1) were measured using an enzyme linked immunosorbent assay.RESULTS:Progenitor cells with a CD133 + /CD45 + CD14 + phenotype were observed in 61%of th patients.Between 1%and 26%of the peripheral bloo mononuclear cells(MNCs)displayed this phenotype Furthermore,a distinct population of c-kit + progenito cells(between 1%and 38%of the MNCs)could b detected in 91%of the patients.Additionally,18% of the patients showed a population of progenito cells(between 1%and 68%of the MNCs)that wa characterized by expression of breast cancer resistanc protein-1.Further phenotypic analysis disclosed tha the circulating precursors expressed CXC chemokin receptor 4,the receptor for SDF-1.In line with thi finding,elevated plasma levels of SDF-1 were presen in all patients and were found to correlate with th number of mobilized CD133 + progenitor cells. | Ursula M Gehling Marc Willems Kathleen Schlagner Ralf A Benndorf Maura Dandri Jrg Petersen Martina Sterneck Joerg-Matthias Pollok Dieter K Hossfeld Xavier Rogiers | 2010 | World Journal of Gastroenterology2010，16，2： | 4 |
| 3 | Folic acid supplementation, MTHFR and MTRR polymorphisms, and the risk of childhood leukemia: the ESCALE study (SFCE)显示文摘 | Alicia Amigou Jérémie Rudant Laurent Orsi Stéphanie Goujon-Bellec Guy Leverger André Baruchel Yves Bertrand Brigitte Nelken Geneviève Plat Gérard Michel Stéphanie Haouy Pascal Chastagner Stéphane Ducassou Xavier Rialland Denis Hémon Jacqueline Clavel | 2012 | Cancer Causes & Control2012，，8： | 2 |
| 4 | Chemical Coal Cleaning Using Selective Oxidation显示文摘 | Stephen R P Edwin J H Xavier A D | 1994 | Fuel1994，73，2： | 1 |
| 5 | Synthesis and characterization of silica/poly (methyl methacrylate)nanocomposite latex particles through emulsion polymerization using a cationic azo initiator 显示文摘 | Xavier J L Guyot A Lanai E B | 2002 | Journal of Colloid and Interface Science2002，250，1： | 1 |
| 6 | The dimen-sionality of the Maslach Burnout Inventory across small business owners and educators 显示文摘 | BOLES J S DEAN D H XAVIER J M R | 2000 | Journal of Vocational Behavior2000，，： | 1 |
| 7 | Characteristics andshort-term prognosis of perioperative myocardial infarction inpatients undergoing noncardiac suigery: a cohort study 显示文摘 | Devereaux PJ Xavier D Pogue J | 2011 | Arm Intern Med2011，154，8： | 1 |
| 8 | Technological Diffusion,Con-vergence ,and Growth 显示文摘 | Barro R J Sala-i-Martin Xavier | 1997 | Journal of Economic Growth1997，2，1： | 1 |
| 9 | Heart-rate profile during exercise as a predictor of sudden death显示文摘 | Xavier J Jean PE Peter JS | 2005 | N Eng J Med2005，12，352： | 1 |
| 10 | Synthesis and characterization of silica/poly(methyl methacrylate) nanocomposite latex particles through emulsion polyme-rization using a cationic azo initiator显示文摘 | LUIZ J XAVIER L GUYOT A | 2002 | Journal of Colloid and Interface Science2002，250，： | 1 |
| 11 | Public Finance in Models of Economic Growth 显示文摘 | Barro R J Xavier Sala-I-Martin | 1992 | Review of Economic Studies1992，，59： | 1 |
| 12 | β-adrenoceptor and in-sulin receptor expression in the skeletal muscle of streptozotocin induced diabetic rats:antagonism by vitamin D and curcumin显示文摘 | Xavier S Sadanandan J George N | | 0，，： | 1 |
| 13 | TGA study examining the effect of pressure and peak temperature on biochar yield during pyrolysis of two-phase olive mill waste显示文摘 | Joan J Manyà F Xavier Roca J Francisco Perales | 2012 | Journal of Analytical and Applied Pyrolysis2012，103，： | 1 |
| 14 | In vitro antibiotic susceptibility of field isolates of Mycoplasma synoviae in Argentina显示文摘 | Cerda R O Giacoboni G I Xavier J A | 2002 | Avian Diseases2002，46，1： | 1 |
| 15 | Biofilm-control strategies based on enzymic disruption of the extracellular polymeric substance matrix-a modelling study 显示文摘 | XAVIER J B PICIOREANU C RAIN S | 2005 | Microbiology2005，151，2： | 1 |
| 16 | Affinity for inor- ganic carbon of Gracilaria tenuistipitata cultured at low and high irradiance 显示文摘 | Mercado J M Carmona R Xavier Niell F | 2000 | Planta2000，210，： | 1 |
| 17 | Dural fistulas of the anterior cranial fossal 显示文摘 | Xavier J Cruz R Stocker A | 2001 | Acta Med Port2001，14，5： | 1 |
| 18 | A Geographical Information System (GIS) Atlas of cephalopod distribution in the Southern Ocean 显示文摘 | Xavier J C Rodhouse P G Trathan P N | 1999 | Antarct Sci1999，11，1： | 1 |
| 19 | Unravelling the pathogenesis of inflammatory bowel disease显示文摘 | Xavier R J Podolsky DK | 2007 | Nature2007，448，7152： | 1 |
| 20 | Risk factors forischaemic and intracerebral haemorrhagic stroke in 22countries(the INTERSTROKE study):a case-controlstudy显示文摘 | O'Donnell M J Xavier D Liu L | 2010 | The Lancet2010，376，9735： | 1 |
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