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| 1 | Effects of Saccharomycesboulardiion fecal short-chain fatty acids and microflora in patients on long-term total enteral nutrition显示文摘AIM: To assess the effects of Sb on fecal flora and shortchain fatty acids (SCFA) in patients on long-term TEN.METHODS: Ten patients (3 females, 7 males, 59±5.5 years),on TEN for a median of 13 mo (1-125), and 15 healthy volunteers (4 females, 11 males, 32±2.0 years) received Sb (0.5 g bid PO) for 6 d. Two stool samples were taken before, on the last 2 d and 9-10 d after treatment, for SCFA measurement and for culture and bacterial identification.Values (mean±SE) were compared using sign tests and ANOVA.RESULTS: Fecal butyrate levels were lower in patients(10.1±2.9 mmol/kg) than in controls (19.2±3.9, P= 0.02).Treatment with Sb increased total fecal SCFA levels in patients (150.2±27.2 vs 107.5±18.2 mmol/kg, P = 0.02)but not in controls (129.0±28.6 vs 113.0±15.2 mmol/kg,NS). At the end of treatment with Sb, patients had higher fecal butyrate (16.0±4.4 vs 10.1 [2.9] mmol/kg, P = 0.004).Total SCFAs remained high 9 d after treatment was discontinued. Before the treatment, the anaerobe to aerobe ratio was lower in patients compared to controls (2.4±2.3 vs69.8±1.8, P = 0.003). There were no significant changes in the fecal flora of TEN patients.CONCLUSION: Sb-induced increase of fecal SCFA concentrations (especially butyrate) may explain the preventive effects of this yeast on TEN-induced diarrhea. | Stéphane M Schneider Fernand Girard-Pipau Jér(o|^)me Filippi Xavier Hébuterne Dominique Moyse Gustavo Calle Hinojosa Anne Pompei Patrick Rampal | 2005 | World Journal of Gastroenterology2005，11，39： | 26 |
| 2 | Folic acid supplementation, MTHFR and MTRR polymorphisms, and the risk of childhood leukemia: the ESCALE study (SFCE)显示文摘 | Alicia Amigou Jérémie Rudant Laurent Orsi Stéphanie Goujon-Bellec Guy Leverger André Baruchel Yves Bertrand Brigitte Nelken Geneviève Plat Gérard Michel Stéphanie Haouy Pascal Chastagner Stéphane Ducassou Xavier Rialland Denis Hémon Jacqueline Clavel | 2012 | Cancer Causes & Control2012，，8： | 2 |
| 3 | Chemical Coal Cleaning Using Selective Oxidation显示文摘 | Stephen R P Edwin J H Xavier A D | 1994 | Fuel1994，73，2： | 1 |
| 4 | The dimen-sionality of the Maslach Burnout Inventory across small business owners and educators 显示文摘 | BOLES J S DEAN D H XAVIER J M R | 2000 | Journal of Vocational Behavior2000，，： | 1 |
| 5 | Technological Diffusion,Con-vergence ,and Growth 显示文摘 | Barro R J Sala-i-Martin Xavier | 1997 | Journal of Economic Growth1997，2，1： | 1 |
| 6 | Public Finance in Models of Economic Growth 显示文摘 | Barro R J Xavier Sala-I-Martin | 1992 | Review of Economic Studies1992，，59： | 1 |
| 7 | In vitro antibiotic susceptibility of field isolates of Mycoplasma synoviae in Argentina显示文摘 | Cerda R O Giacoboni G I Xavier J A | 2002 | Avian Diseases2002，46，1： | 1 |
| 8 | Affinity for inor- ganic carbon of Gracilaria tenuistipitata cultured at low and high irradiance 显示文摘 | Mercado J M Carmona R Xavier Niell F | 2000 | Planta2000，210，： | 1 |
| 9 | Dural fistulas of the anterior cranial fossal 显示文摘 | Xavier J Cruz R Stocker A | 2001 | Acta Med Port2001，14，5： | 1 |
| 10 | Unravelling the pathogenesis of inflammatory bowel disease显示文摘 | Xavier R J Podolsky DK | 2007 | Nature2007，448，7152： | 1 |
| 11 | Growth process and surface acoustic wave characteristics of LiNbO3/Diamond/Silicon multilayered structures显示文摘 | ELHAD J D XAVIER L DENIS R | 2003 | Jpn J Appl Phys2003，42，： | 1 |
| 12 | Convergence显示文摘 | BARRO R J Sala-i-Martin Xavier | | 0，，： | 1 |
| 13 | Rassf fam- ily of tumor suppressor polypeptides 显示文摘 | AVRUCH J XAVIER R BARDEESY N | 2009 | J Biol Chem2009，284，11： | 1 |
| 14 | Management of carotid arterystenosis:comparing endarterectomy and stentmg显示文摘 | Hanel R A Xavier A R Kirmani J F | 2003 | Curt Cardio Ⅰ Rep2003，5，2： | 1 |
| 15 | The scaffold protein CNK1 interacts with the tumor suppressor RASSFIA and augments RASSF1A-induced cell death 显示文摘 | RABIZADEH S XAVIER R J ISHIGURO K | 2004 | J Biol Chem2004，279，29： | 1 |
| 16 | The dimensionality of the Maslach Burnout Inventory across small business owners and educators显示文摘 | Boles J S Dean D H Xavier J M R Short J C Wang G P | 2000 | Journal of Vocational Behavior2000，56，： | 1 |
| 17 | Unravelling the pathogenesis of inflammato- ry bowel disease显示文摘 | Xavier R J Podolsky D K | 2007 | Nature2007，448，7152： | 1 |
| 18 | Unravelling the pathogenesis of inflammatory bowel disease显示文摘 | Xavier R J Podolsky DK | 2007 | Lancet2007，448，7152： | 1 |
| 19 | Public finance in models of economic growth显示文摘 | Barro R J Xavier S | 1992 | Review of Economic Studies1992，59，： | 1 |
| 20 | Copper phthalocyanine as an efficient dopant in development of solar cells 显示文摘 | INIGO A R XAVIER F P GOLDSMITH G J | 1997 | Material Research Bulletin1997，32，5： | 1 |
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