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您的检索式：作者名="XIAOSU SONG"
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| 1 | Disease profile and plasma neutralizing activity of postvaccination Omicron BA.1 infection in Tianjin,China:a retrospective study显示文摘Dear Editor,SARS-CoV-2 Omicron variant BA.1 first emerged on the Chinese mainland on January 8,2022,in Tianjin and caused a large wave of infections.1 Four rounds of mass testing of its~14 million residents were launched on January 9,12,15,and 20,respectively.As of February 7,2022,a total of 430 individuals were tested positive for Omicron BA.1,with no new infections detected for the following 16 days.In the Chinese mainland,the most delivered vaccines are inactivated vaccines.As of January 8,2022,up to 93.2%of Tianjin’s residents had been vaccinated with at least one dose.2 We investigated the protection conferred by vaccination against Omicron BA.1 by examining the breakthrough infections among vaccinees as compared with unvaccinated cases.Our study population comprised all 430 cases during the outbreak of Omicron BA.1 in Tianjin. | Hong Zheng Yunlong Cao Xiaosu Chen Fengmei Wang Ye Hu Weiliang Song Yangyang Chai Qingqing Gu Yansong Shi Yingmei Feng Shuxun Liu Yan Xie Xiaoliang Sunney Xie Wentao Jiang Zhongyang Shen | 2022 | Cell Research2022，32，8： | 12 |
| 2 | The electric self-heating behavior of carbon black loaded high density polyethylene composites显示文摘 | Song Yihu YI Xiaosu Pan Yi | 2000 | Journal of Materials Science Letters2000，19，： | 1 |
| 3 | Novel anomaly detection approach for telecommunication network proactive performance monitoring显示文摘The mode of telecommunication network management is changing from“network oriented”to“subscriber oriented”.Aimed at enhancing subscribers’feeling,proactive performance monitoring(PPM)can enable a fast fault correction by detecting anomalies designating performance degradation.In this paper,a novel anomaly detection approach is the proposed taking advantage of time series prediction and the associated confidence interval based on multiplicative autoregressive integrated moving average(ARIMA).Furthermore,under the assumption that the training residual is a white noise process following a normal distribution,the associated confidence interval of prediction can be figured out under any given confidence degree 1–αby constructing random variables satisfying t distribution.Experimental results verify the method’s effectiveness. | Yanhua YU Jun WANG Xiaosu ZHAN Junde SONG | 2009 | Frontiers of Electrical and Electronic Engineering in China2009，4，3： | 0 |
| 4 | Semaphorin 7A promotes human vascular smooth muscle cell proliferation and migration through theβ-catenin signaling pathway显示文摘Background:Vascular smooth muscle cells(VSMCs)undergo a conversion from a contractile phenotype to a proliferative synthetic phenotype,contributing to the pathogenesis of cardiovascular diseases.Semaphorin 7A(SEMA7A)is a glycosylphosphatidylinositol-anchored membrane protein that plays an important role in vascular homeostasis by regulating endothelial cell behaviors.However,the expression and role of SEMA7A in VSMCs remain unclear.Methods:In this study,we screened for VSMC-regulating genes in publicly available datasets and analyzed the expression of SEMA7A in human coronary artery smooth muscle cells(hCASMCs)treated with platelet-derived growth factor-BB(PDGF-BB).The effects of SEMA7A overexpression and knockdown on hCASMC proliferation and migration were examined.The signaling pathways involved in the action of SEMA7A in hCASMCs were determined.Results:Bioinformatic analysis showed that SEMA7A was significantly dysregulated in VSMCs treated with oxidized low-density lipoprotein or overexpressing progerin,a pro-atherogenic gene.The PDGF-BB stimulation led to a concentration-and time-dependent induction of SEMA7A.Depletion of SEMA7A attenuated PDGF-BB-induced hCASMC proliferation and migration.Conversely,overexpression of SEMA7A enhanced hCASMC proliferation and migration.Mechanistically,SEMA7A stimulated the activation of theβ-catenin pathway and upregulated c-Myc,CCND1,and MMP7.Knockdown ofβ-catenin impaired SEMA7A-induced hCASMC proliferation and migration.Conclusions:SEMA7A triggers phenotype switching in VSMCs through theβ-catenin signaling pathway and may serve as a potential therapeutic target for cardiovascular diseases. | XIAOSU SONG FEN GAO HONG LI WEIWEI QIN CHANJUAN CHAI GUOJUAN SHI HUIYU YANG | 2023 | BIOCELL2023，47，4： | 0 |
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