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| 1 | Microbial community structure of ethanol type fermentation in biohydrogen production显示文摘 | Ren NQ Xing DF Rittmann BE Zhao LH Xie TH Zhao X | 2007 | 中国生物学文摘2007，21，7： | 16 |
| 2 | Novel functional proteins interact with midkine in hepatic cancer cells显示文摘BACKGROUND: Midkine is a heparin-binding growth factor that promotes the proliferation, survival, migration and differentiation of various target cells. Midkine plays an important role in tumorigenesis and tumor progression, and is overexpressed in many human malignant tumors. Patients with high tumor midkine expression frequently have a worse prognosis than those with low expression. The present study was designed to investigate the interaction network of midkine in hepatic cancer cells, and to elucidate its role in hepatocellular carcinoma. METHODS: DNA encoding full-length midkine was cloned into pDBLeu vector to serve as bait in yeast two-hybrid screening to identify interacting proteins. Candidate proteins were examined on SC-Leu-Trp-His+3-AT (20 mmol/L) plates and assayed for X-gal activity, then sequenced and classified according to the GenBank. Finally, identified proteins were expressed by the in vitro expression system pCMVTnT, and protein interactions were confirmed by co-immunoprecipitation. RESULTS: Using the yeast two-hybrid system, we found 6 proteins that interacted with midkine: NK-kappa-B inhibitor alpha (I-κ-B-α), Dvl-binding protein naked cuticle 2, granulin, latent active TGF-β binding protein 3, latent active TGF-β binding protein 4, and phospholipid scramblase 1. In vitro co-immunoprecipitation demonstrated that all identified proteins directly interacted with midkine.CONCLUSION: The identification of midkine-interacting proteins in hepatic cancer cells indicates that midkine is a multifunctional factor that may participate in cell migration, differentiation, and proliferation, and is also associated with the multicellular response feedback during the development of hepatocellular carcinoma. | Qiang Yan, Hui-Lian Huang, Xing Yao, Jing Li, Li-Qin Li, Jing Zhong, Li-Shan Min, Li-Cheng Dai and Shu-Sen Zheng Department of Hepatobiliary and Pancreatic Surgery, Huzhou Central Hospital (Yan Q and Yao X) Huzhou Key Laboratory of Molecular Medicine, Affiliated Central Hospital of Huzhou Teachers College (Huang HL, Li J, Li LQ, Zhong J, Min LS and Dai LC), Huzhou 313000, China Division of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China (Yan Q and Zheng SS) | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，3： | 7 |
| 3 | Centro-parietal N200: An event-related potential component specific to Chinese visual word recognition显示文摘Almost all written languages currently used in the world are alphabetic or phonologically-based scripts (e.g., English) whose word recognition involves discrimination of one-dimensional linear combinations of several dozens of letters or phonological units, except written Chinese whose vocabulary consists of a large number of block characters, the analysis of which relies on the extraction of 2-dimensional form information at multiple levels including radical, character, and multiple-character word. Whether the dramatic contrast between the 2 types of orthography leads to distinctive mental processes is a fundamental question in psycholinguistic research unanswered in the past three decades. Using event-related potentials and visual lexical decision tasks, we asked native Chinese speakers to discriminate between real Chinese words and pseudoor non-words and observed a widespread negative deflection with centro-parietal focus elicited 200 ms post-stimulus onset. This N200 response showed a clear and large amplitude enhancement upon word repetition and seems to be specific to Chinese as no similar effects had been reported in word recognition studies involving alphabetic scripts under similar experimental conditions. Further evidence showed that this N200 could not be attributed to non-linguistic sensori-perceptual processes, nor phonological or semantic processes, but likely reflects very early identification of the orthography of individual words involving extensive and higher-level visual analysis. Recently the first author proposed a meaning-spelling theory of written Chinese vocabulary proposing that the Chinese and alphabetic scripts are the only 2 possible logical types of mature human writing systems, and that the former is more thoroughly a visual language compared with the latter and thus shall emphasize more of visual processing. Reinforcing each other, the meaning-spelling theory and the discovery of the centro-parietal N200 reveal the uniqueness of Chinese both theoretically and empirically, and provide strong arguments for the intrinsic distinction between written Chinese and alphabetic scripts. | ZHANG John X FANG Zhuo DU YingChun KONG LingYue ZHANG Qin XING Qiang | 2012 | Chinese Science Bulletin2012，57，13： | 6 |
| 4 | 茶叶摄入与中国成年人高密度脂蛋白胆固醇浓度纵向变化的关系显示文摘茶叶摄入与高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)浓度的年龄相关变化之间的关系仍不清楚。该研究目的是探索茶摄入量与HDL-C浓度纵向变化之间的关系。研究人员通过调查问卷评估基线(2006年)的茶叶消费量,并在2006、2008、2010和2012年测量了未患有心血管病或癌症. | 刘莉 叶鹏 Huang S Li J Wu Y Ranjbar S Xing A Zhao H Wang Y Shearer GC Bao L Lichtenstein AH Wu S Gao X | 2018 | 中华高血压杂志2018，26，8： | 5 |
| 5 | Pathways of N 2 O emission from rice paddy soil显示文摘 | X Yan S Shi L Du G Xing | 2000 | Soil Biology and Biochemistry2000，，3： | 2 |
| 6 | Induction and expression of beta-calcitonin generelated peptide in rat T lymphocytes and its significance 显示文摘 | Xing L Guo J Wang X | 2000 | J Immunol2000，165，8： | 2 |
| 7 | Optimization of growth and jaceosidin in callus and cell suspension cultures of Saussurea medusa 显示文摘 | Zhao D X Xing J M Li M Y | 2001 | Plant Cell Tiss Org2001，67，： | 2 |
| 8 | Variations of bacterioplankton community composition during Microcystis spp. blooms in a shallow eutrophic lake显示文摘 | Xing P Kong FX Cao HS Zhang M Tan X | 2007 | 中国生物学文摘2007，21，8： | 2 |
| 9 | UV photo-stabilization of tetrabutyl titanate for aramid fibers via sot-gel surface modification 显示文摘 | Xing Y J Ding X | 2007 | Journal of Applied Polymer Science2007，103，5： | 1 |
| 10 | Temperature dependence of energy gaps in dimerized Heisenberg chain显示文摘 | Jiang X F Xing D Y Chen H | 2002 | Chinese Phys Lett2002，19，4： | 1 |
| 11 | Methane and nitrous oxide emissions from rice paddy fields as affected by nitrogen fertilisers and water management显示文摘 | Cai Z C Xing G X Yan X Y | 1997 | Plant Soil1997，196，： | 1 |
| 12 | Susceptibility to gastric cardia adenocarcinoma and genetic polymorphisms in methylenetetrahydrofolate reductase in an at-risk Chinese population显示文摘 | Miao X Xing D Tan W | 2002 | Cancer Epidemiol Biomarkers Prev2002，11，11： | 1 |
| 13 | Methane and nitrous oxide emissions from rice paddy fields as affected by nitrogen fertilizers and water management显示文摘 | Cai Z C Xing G X Yan X Y | 1997 | Plant and Soil1997，196，1： | 1 |
| 14 | Narrow-band interfe-rence suppression for SAR based on complex empirical mode decomposition显示文摘 | ZHOU F XING M BAI X | 2009 | IEEE Geoscience and Remote Sensing Letters2009，6，3： | 1 |
| 15 | Overexpression of glucose- regulated protein 78 in colon cancer显示文摘 | Xing X Lai M Wang Y | 2006 | Clin Chim Acta2006，364，12： | 1 |
| 16 | Transitional cell carcinoma in renal transplant recipients: a single cen- ter experience显示文摘 | LI X B Xing N Z Wang Y | 2008 | Int J Urol2008，15，： | 1 |
| 17 | Reducing environmental risk by improving N management in intensive Chinese agricultural systems显示文摘 | Ju X T Xing G X Chen X P | 2009 | PNAS2009，106，： | 1 |
| 18 | Overexpression of activated nuclear factor-k B in aorta of patients with coro- nary atherosclerosis 显示文摘 | Zhang W Xing S S Sun X L | 2009 | Clin Cardiol2009，32，12： | 1 |
| 19 | Porcine TEF1 and RTEFI: Mo- lecular characterization and association analyses with growth traitsr显示文摘 | Xu X Xing S Du Z Q | 2008 | Comparative Biochemistry and Physiology Part B: Bi-ochemistry and Molecular Biology2008，150，4： | 1 |
| 20 | UV-curable functionalized graphene oxide/polyurethane acrylate nanocomposite coatings with enhanced thermal stability and mechanical properties显示文摘 | YU B WANG X XING W Y | 2012 | Industrial & Engineering Chemistry Research2012，51，14： | 1 |
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