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| 1 | Necessity and indications of invasive treatment for Budd-Chiari syndrome显示文摘BACKGROUND:The development of collaterals in Budd-Chiari syndrome has been described and these collaterals play an important role in the presentation of this disease.These collaterals are diagnostic and their use in management strategy has never been evaluated.This study aimed to investigate the indications,feasibility and necessity of invasive treatment for patients with Budd-Chiari syndrome and to determine whether such a strategy is necessary for optimal management.METHODS:Twenty-nine patients who had been treated at our unit were enrolled in this study.Based on physical and biochemical examination,and hemodynamic compensation by collaterals,18 patients underwent radiological intervention (group A),while the other 11 had no invasive treatment (group B).The related hemodynamic parameters were acquired when percutaneous angiography was performed.RESULTS:In group A,all patients underwent successfully inferior vena cava (IVC) balloon angioplasty with or without stenting.Four patients also underwent hepatic vein angioplasty.In these patients,the mean IVC pressure before and after treatment was statistically different (29.3±9.2 vs 15.1±4.6 mmHg,P<0.01).The mean IVC pressure was much lower in group B than in group A (12.9±2.4 vs 29.3±9.2 mmHg,P<0.01),but there was no difference from that of the patients after radiological treatment (12.9±2.4 vs 15.1±4.6 mmHg,P>0.05).Median follow-up was 32.3 months (mean 21.3 months;range 3-61 months).In the course of follow-up,the patients in group A survived with good systemic status except for re-stenosis in one patient who underwent re-canalization of the IVC.In group B,10 patients had good systemic status except one patient who had a meso-caval shunt because of deterioration.CONCLUSIONS:The rationale of 'early diagnosis and early treatment' is not suitable for all patients with Budd-Chiari syndrome.Satisfactory survival can be achieved in some patients without invasive treatment,who are completely compensated by rich collaterals.Nonetheless,a positive treatment procedure should be performed if the patient's situation worsens in the course of regular follow-up. | Department of General Surgery (Fu Y,Sun YL,Ma XX,Xu PQ,Feng LS,Tang Z and Luo CH),Institute of Hepatic Vascular Disease (Sun YL),Department of Radiological Intervention (Guan S and Wang ZW),First Affiliated Hospital,Zhengzhou University School of Medicine,Zhengzhou 450052,China | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 10 |
| 2 | Cloning of environmental genomic fragments as physical markers for monitoring microbial populations in coking wastewater treatment system显示文摘 | Yan X Xu ZM Feng XX Liu YD Liu BB Zhang X J Zhu CG Zhao LP | 2007 | 中国生物学文摘2007，21，8： | 4 |
| 3 | Relationship between state transition and photoinhibition of photosynthesis in wheat leaves显示文摘IT is well known that state transitions can keep even distribution of excitation energy betweenthe two photosystems (PS Ⅱ and PS Ⅰ), favoring efficient operation of the photosyntheticapparatus. However, state transitions are usually thought to be associated with low light con-ditions. Its physiological significance under high light conditions is still a controversial is-suc. Many people think that state transitions occur and take significant effect only under | Tan, XX Xu, DQ Shen, YG | 1997 | Chinese Science Bulletin1997，42，21： | 2 |
| 4 | Cell cycle-dependent phosphorylation of Disabled-2 by cdc2显示文摘 | He J Xu J Xu XX | 2003 | Oncogene2003，22，29： | 1 |
| 5 | Metabolite concentration rati- os in thalami of patients with migraine and trigeminal neu- ralgia measured with 1 H-MRS 显示文摘 | Gu T Ma XX Xu YH | 2008 | Neurol Res2008，30，3： | 1 |
| 6 | Clinical observation on buflomedil infusion on acute ischemic stroke显示文摘 | LI HJ WANG XX XU YL | 2000 | Chinese Journal of Clinical Pharmacologeutics and Therapeutics2000，5，4： | 1 |
| 7 | Cloning of a novel phosphoprotein regulated by colony-stimulating factor 1 shares a domain with the drosophila disabled gene product显示文摘 | Xu XX Yang W Jackowsko S | 1995 | Biol Chem1995，270，14： | 1 |
| 8 | A mechanistic study on reducedtoxicity of irinotecan by coadministered thalidomide,a tumor nec-rosis factor-a inhibitor显示文摘 | Yang XX Hu ZP Xu AL | 2006 | J Pharmacol Exp Ther2006，319，1： | 1 |
| 9 | Metal-induced expressing of mammal Metallothionein-1 gene in cyanobaeteria to promoto cadmium-binding preferences 显示文摘 | Guo XX Shi DJ Xu XD | 1999 | Applied Microbiology and Biotechnology1999，52，： | 1 |
| 10 | Luteolin promotes long-term potentiation and improves cognitive functions in chronic cerebral hypoperfused rats显示文摘 | Xu B Li XX He GR | 2010 | European Journal of Pharrnacology2010，627，1： | 1 |
| 11 | Influences of Dengzhan Xixin injection on blood viscosity in patients with high blood viscosity 显示文摘 | Xu QY Li XX | 1995 | Chin J New Drugs Clin Rein1995，14，4： | 1 |
| 12 | Microbiological study of pathogenic bacteria isolated from paediatric wound infec- tions following the 2008 Wenchuan earthquake 显示文摘 | Ran YC Ao XX Liu L Fu YL Tuo H Xu F | 2010 | Scand J Infect Dis2010，42，5： | 1 |
| 13 | Testicular denervation in prepuberty rat inhibits seminiferous tubble development and spermatogenesis显示文摘 | Huo SY Xu ZH Zhang XX | 2010 | J Reprod Develop2010，56，4： | 1 |
| 14 | Cell cycle-dependent phosophorylation of disabled-2 by cde2显示文摘 | He J Xu J Xu XX | 2003 | Oncogene2003，22，29： | 1 |
| 15 | The effect of TGF-beta1 and SMAD7 gene transfer on the phenotypic changes of rat alveolar epithelial cells显示文摘 | Xu GP Li QQ Cao XX | 2007 | Cell Mol Biol Lett2007，12，3： | 1 |
| 16 | Surgical treatment of 1360 cases of Budd-Chiari syndrome:20-year experience显示文摘 | Xu PQ Ma XX Ye XX | 2004 | Hepatobil Pancreat Dis Int2004，3，3： | 1 |
| 17 | Identification andfunctional characterization of mitochondrial carrierMrs4 in Candida albicans显示文摘 | Xu N Cheng XX Yu QL | 2012 | FEMS YeastResearch2012，12，7： | 1 |
| 18 | Radical removal of membranous obstruction of inferior venaeava显示文摘 | Xu PQ Zhang SJ Ye XX | 1993 | Chin Med J1993，106，3： | 1 |
| 19 | Clini- cal investigation of off-flap epi-LASIK for moderate to high myo- pia 显示文摘 | Wang QM Fu AC Yu Y Xu CC Wang XX Chen SH | 2008 | Invest Ophthalmol Vis Sci2008，49，5： | 1 |
| 20 | Bioinformatics analysis identifies miR-221 as a core regulator in hepatocellular carcinoma and its silencing suppresses tumor properties 显示文摘 | He XX Guo AY Xu CR | 2014 | Oncol Pep2014，2，3： | 1 |
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