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| 1 | Inhibitory activity of polysaccharide extracts from three kinds of edible fungi on proliferation of human hepatoma SMMC-7721 cell and mouse implanted S180 tumor显示文摘AIM To determine the activities ofpolysaccharide extracts from Flammulina velutipes (Curt. ex Fr. ) Sing (FV), Lentinusedodes (LE) and Agaricus bisporus Sing (AB)on the proliferation of human hepatoma SMMC-7721 cells in vitro and on mouse implanted S-180tumors in vivo.METHODS The polysaccharide extracts were isolated from the fruit bodies of FV, LE and AB by the methods of hot-water extraction, Sevag’sremoval of proteins, ethanol precipitation,trypsin digestion and ethanol fractionalprecipitation. Human hepatoma SMMC-7721 cells were treated with 50 mg/L Polysaccharide extracts, and the mitosis index, mitochondria activity and cell proliferation were detected at different times in both control and experimental groups. The mice with S-180 implanted tumors were injected with the polysaccharide extracts at 24 mg/ kg body weight for 9 d and the tumorweight was measured on the 15th day.RESULTS The mitosis index of hepatoma cells in vitro could be significantly decreased by treatment with the polysaccharide extracts fromthe three kinds of edible fungi (P < 0 .005 ). Thecell numbers and mitochondria activity of SMMC7721 cells treated with polysaccharide extracts were lower than those in control groups (P <0.005). The inhibition rates of polysaccharide extracts against implanted S-180 tumors in mice were 52.8%, 56.6% and 51 .9% respectivelycompared with that in c0ntrol gr0ups.CONCLUSI0N The POIysaccharide extractsfrom the three kinds of edible fungi could inhibitnot only the Cultured malignant cells in vitfO butalso impIanted Sl80 tum0r i0 vivo. | Jiang SM Xiao ZM Xu ZH | 1999 | World Journal of Gastroenterology1999，5，5： | 5 |
| 2 | Syntax of first-order lattice valued logic system FM显示文摘PAVELKA in ref. [1] established a propositional logic system whose truth values domain is an enriched residuated lattice and obtained some beautiful results. In order to study more general lattice valued logic systems, we proposed the concept of lattice implication algebra, discussed the corresponding lattice valued propositional logic system, and established a | Xu, Y Qin, KY Song, ZM | 1997 | Chinese Science Bulletin1997，42，16： | 4 |
| 3 | Cloning of environmental genomic fragments as physical markers for monitoring microbial populations in coking wastewater treatment system显示文摘 | Yan X Xu ZM Feng XX Liu YD Liu BB Zhang X J Zhu CG Zhao LP | 2007 | 中国生物学文摘2007，21，8： | 4 |
| 4 | SELECTIVE DIMERIZATION OF BUTANAL TO BUTYL BUTYRATE CATALYZED BY LANTHANOCENE/n-BuLi SYSTEMS显示文摘SELECTIVEDIMERIZATIONOFBUTANALTOBUTYLBUTYRATECATALYZEDBYLANTHANOCENE/n-BuLiSYSTEMS￥FanXU,LiLuZHANG,MingYAO,YuanChenDING,ZhiMi... | Xu, F Zhang, LL Yao, YM Ding, YC Bai, ZM Shen, Q | 1995 | Chinese Chemical Letters1995，6，7： | 2 |
| 5 | Non-motor symptoms of Parkinson's disease in China: a review of the literature 显示文摘 | Chen W Xu ZM Wang G | 2012 | Parkinsonism Relat Disord2012，18，5： | 1 |
| 6 | RANKL, OPG and CTRmRNA expression in ihe temporomandibular joint in rheuma-toid arthritis显示文摘 | Liu WW Xu ZM Li ZQ | 2015 | Exp Ther Med2015，10，3： | 1 |
| 7 | Capabilities of different cooking oils in prevention of cholesterol oxidation during heating显示文摘 | Xu ZM Zhang T Witoon P | 2005 | Journal of the American Oil Chemists’Society2005，82，4： | 1 |
| 8 | Computerized classification study on 680 clinical confirmed SARS patients in Xiao Tang Shan Hospital 显示文摘 | Dong J Cao XT Liu ZM Xu HM Li YP Sun X Wang L Zhou YC | 2004 | Chinese Journal of Evidence-Based Medicine2004，4，5： | 1 |
| 9 | Predictive chemotherapy of advanced breast cancer directed by MTT assay in vitro 显示文摘 | Xu JM Song ST Tang ZM | 1999 | Breast Cancer Res Treat1999，53，1： | 1 |
| 10 | Expression of COX-2 mRNA in peripheral blood monocytes from patients with acute myocardial infarction and its significance显示文摘 | Zhao SP Deng P Huang HG Xu ZM Dai HY Hong SC | 2005 | Clin Chem2005，51，11： | 1 |
| 11 | Synthesis and antihepatitis B virus activities of Matijin-Su derivatives显示文摘 | Xu BX Huang ZM Liu CX | 2009 | Bioorg Med Chem2009，17，8： | 1 |
| 12 | Synthesis and biological evaluation of Matijin-Su derivatives as potent antiHBV agents显示文摘 | Qiu JY Xu BX Huang ZM | 2011 | Bioorg Med Chem2011，19，18： | 1 |
| 13 | Atorvastatin reduces plasma MCP-1 in patients with acute coronary syndrome显示文摘 | Xu ZM Zhao SP Li QZ | 2003 | Clin Chim Acta2003，338，12： | 1 |
| 14 | Ultrasonic communicationin frogs显示文摘 | Feng AS PM Narins CH Xu WY Lin ZL Yu Q Qiu ZM Xu and JX Shen | 2006 | Nature2006，440，： | 1 |
| 15 | The novel gene LRP15 is regulated by DNA methylation and confers increased efficiency of DNA repair of ultraviolet-induced DNA damage显示文摘 | Xu ZM Gao WB Mei Q | 2008 | BMB reports2008，41，3： | 1 |
| 16 | Synthesis and anti-hepa- titis B virus activities of Matijin-Su derivatives 显示文摘 | Xu BX Huang ZM Liu CX | 2009 | Bioorganic & Medicinal Chemistry2009，17，8： | 1 |
| 17 | Level and distribution of DDT in surface soils from Tianjin, China显示文摘 | Gong ZM Tao S Xu FL Dawson R Liu W Cui YH Cao J Wang X J Shen WR Zhang W J Qing BP Sun R | 2004 | Chemosphere2004，54，： | 1 |
| 18 | Synthesis and biological evaluation of Matijin-Su derivatives as potent anti-HBV agents 显示文摘 | Qiu JY Xu BX Huang ZM | 2011 | Bioorg&MedChem2011，19，18： | 1 |
| 19 | Thermal dynamic properties of isoflavones during dh'y heating 显示文摘 | Yue XH Abdallah AM Xu ZM | 2010 | International Journal of Food Science and Technology2010，45，9： | 1 |
| 20 | Mechanisms in noise induced permanent hearing loss an evoked otoacoustic emission and auditory brainstem response study显示文摘 | Xu ZM Vinck B De Vel E | 1998 | J Laryngol Otol1998，112，12： | 1 |
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