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	题名	作者	年代	出处	被引量
1	Induction of mucosal and systemic immune response by single-dose oral immunization with biodegradable microparticles containing DNA encoding HBsAg显示文摘	He XW Wang F Jiang L Li J Liu SK Xiao ZY Jin XQ Zhang YN He Y Li K Guo YJ Sun SH	2005	第二军医大学学报2005，26，10：	5
2	Effect of Selenium Supplementation on Activity and mRNA Expression of Type 1 Deiodinase in Mice With Excessive Iodine Intake显示文摘Objective To investigate the effect of selenium supplementation on the selenium status and selenoenzyme, especially the activity and mRNA expression of type 1 deiodinase (D1) in mice with excessive iodine (EI) intake and to explore the mechanism of selenium intervention on iodine-induced abnormities. Methods Weanling female BALB/c mice were given tap water or 3 mg/L of iodine or supplemented with 0.5 mg/L or 1.0 mg/L of selenium in the presence of excessive iodine for 5 months. Selenium status, thyroid hormone level, hepatic and renal D1 activity and mRNA expression were examined. Results Excessive iodine intake significantly decreased the selenium concentration in urine and liver, and the activity of glutathione peroxidase (GSH-Px) in liver. Meanwhile, serum total T4 (TT4) increased while serum total T3 (TT3) decreased. Hepatic D1 enzyme activity and mRNA expression were reduced by 33% and 86%, respectively. Renal D1 enzyme activity and mRNA were reduced by 30% and 55%, respectively. Selenium supplementation obviously increased selenium concentration, activity of GSH-Px and D1 as well as mRNA expression of D1. However, increasing the supplementation of Se from 0.5 to 1.0 mg/L did not further increase selenoenzyme activity and expression. Conclusion Relative selenium deficiency caused by excessive iodine plays an essential role in the mechanism of iodine-induced abnormalities. An appropriate dose of selenium supplementation exercises a beneficial intervention.	XUE-FENG YANG XIAO-HUI HOU JIAN XW HUAI-LAN GUO CHEN-JIANG YING XIAO-YI CHEN XIU-FA SUN	2006	Biomedical and Environmental Sciences2006，19，4：	5
3	Hydrotherrnally grown oriented ZnO nanorod arrays for gas sensing applications显示文摘	JX Wang XW Sun Y Yang	2006	Nanotechnology2006，17，：	1
4	Fetal microchimerism in the maternal mouse brain:a novel population of fetal progenitor or stem cells able to cross the blood-brain barrier?显示文摘	Tan XW Liao H Sun L	2005	Stem Cells2005，23，10：	1
5	The important roles of transpoter protein in drug delivery显示文摘	Sun J Lu R Fan XW	2007	Chin Pharm J2007，42，3：	1
6	Thulium laser versus standard transurethral resection of the prostate:a randomized prospective trial显示文摘	XIA SJ ZHUO J SUN XW	2008	Eur Urol2008，53，2：	1
7	Determination of tetracyclines in food samples by molecularly imprinted monolithic column coupling with high performance liquid chromatoaphy显示文摘	Sun XL He XW Zhang YK	2009	Talanta2009，79，：	1
8	Overexpression of 14-3-3 Protein Protects Pheochromocytoma Cells Against 1-methyl-4-Phenylpyridinium Toxicity 显示文摘	CHEN XW SUN SG CHENG DB	2006	Neurosci Bull(S1673-7067)2006，22，5：	1
9	Overexpression of 14-3-3 protein protects pheochromocytoma cells against 1-methyl-4-phcny- lpyridinium toxicity显示文摘	Chen XW Sun SG Cheng DB	2006	Neurosci Bull2006，22，：	1
10	Beta-catenin siRNA regulation of apoptosis-and angiogenesis-related gene ex-pression in hepatocellular carcinoma cells:potential uses for gene therapy显示文摘	Wang XH Sun X Meng XW	2010	Oncol Rep2010，24，4：	1
11	UXT is a novel and essential cofactor in the NF-KB transcriptional enhanceosome 显示文摘	Sun SG Tang YJ Lou XW	2007	J Cell Biol2007，173，7：	1
12	Thulium laser versus standard transurethral resection of the prostate:a randomized prospective trial显示文摘	Xia SJ Zhuo J Sun XW	2008	Eur Uro12008，53，：	1
13	Overexpressiou of 14-3-3 protein protects pheuchromocytoma cells againsl l-melhyl-4-phenylpyridinium toxicity 显示文摘	Chen XW Sun SG Cheng DB	2006	Neurosci Bull2006，22，5：	1
14	Fetal microchimerism in the maternal mouse brain:a novel population of fetal progenitor or stem cells able to cross the blood-brain barrier显示文摘	Tan XW Liao H Sun L		0，，10：	1
15	Nonsten- ted versus routine stented ureteroscopic holmium laser lithotripsy:a prospective randomized trial显示文摘	Shao Y Zhuo J Sun XW	2008	Urol Res2008，36，25：	1
16	Pulmonary function param- eters in high-resolution computed tomography phenotypes of chronic obstructive pulmonary disease显示文摘	Sun XW Gu SY Li QY	2015	Am J Med Sci2015，349，3：	1
17	Quantitative evaluation of Renshengquipi Wan by merging capillary electrophoresis fingerprints and infrared spectrum fingerprints显示文摘	Sun GX Dou XW	2012	Asian Journal of Traditional Medicines2012，7，5：	1
18	Thulium laser versus stan-dard transurethral resection of the prostate:a randomizedprospective trial显示文摘	XIA SJ ZHUO J SUN XW	2008	Eur Urol2008，53，：	1
19	Validation of a Novel Risk Score for Severity of Illness in Acute Exacerbations of COPD 显示文摘	Shorr AF Sun XW Johannes RS	2011	Chest2011，140，5：	1
20	Overexpression of 14-3-3 protein protects pheochromocytoma cells against 1-methyl-4-phenylpyridinium toxicity 显示文摘	Chen XW Sun SO Cheng DB	2006	Neurosci Bull2006，22，5：	1

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