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| 1 | Geochemistry and petrogenesis of Jurassic high Sr/low Y granitoids in eastern China: Constrains on crustal thickness显示文摘The Jurassic high Sr/low Y granitoids in eastern China are characterized by high Sr/Y (27-166) and La/Yb (14-66) ratios, low abundance in Y (6-21μg/g) and Yb (0.5-2.0μg/g), comparable with those of adakites defined by Defant et al. Thus, they were recently considered as adakitic rocks by some researchers. Compared with the typical adakites in circum-Pacific margins, however, these high Sr/low Y granitoids have higher K2O (-3.5%) but lower A12O3 (-16.0%) as well as lower Mg#(-38) and δSrN (-1.23) values. Furthermore, they show relatively flat HREE patterns with Y/Yb values of -10 close to the chondritic value. These geochemical characteristics indicate a residue mineral assemblage of hornblende, garnet and plagioclase for these high Sr/low Y granitoids melt. Thus, they were generated by partial melting at 9-13 kbar (30-45 km in depth), similar to the Archaean high-Al TTG rather than the modern adakites. Generation of these high Sr/low Y granitoids cannot be considered as evidence for a thickened | Ge, XY Li, XH Chen, ZG Li, WP | 2002 | Chinese Science Bulletin2002，47，11： | 51 |
| 2 | A New Capillary Electrophoresis Apparatus with Piezoelectric Ceramics High Voltage Source and Amperometric Detector显示文摘IntroductionHighperformancecapiliar}'electrophoresis(HPCE)isanewanalyticaltechnology'rapidly'developedinrecentyears.Withtheadvantagesofsmallsample.highsensitivity,highresolution.rapidanalysisandverycheaprunning,ithasbeenappliedinchemistry'.lifescienc... | Chen, ZG Mo, JYM Yang, XY Wang, LS Mei, XT Zhang, MS | 1999 | Chinese Chemical Letters1999，10，3： | 19 |
| 3 | RELIABILITY ANALYSIS OF FRP LAMINATED PLATES WITH CONSIDERATION OF BOTH INITIAL IMPERFECTION AND FAILURE SEQUENCE显示文摘A probabilistie progressive failure analyzing method is applied to estimating the reliability of asimply supported laminated eomposite plate with an initial imperfection under bi-axial eompression load.Theinitial imperfection and the strength parameters are considered as random variables.Ply-level failure proba-bility is evaluated by the first order reliability method(FORM)together with the Tsai-Wu strength eriterionand Tan criterion.Current stresses in the laminated structure are calculated by the classical lamination theorywith the stiffness modified based on the last step ply failure.Probabilistieally dominant ply-level failure se-quences leading to overall system failure are identified,based on which the system failure probability is esti-mated.A numerieal example is presented to demonstrate the methodology proposed.Through parameter stud-ies it is shown that the deviation of the initial imperfeetion and some of the strength parameters largely influ-ence the system reliability. | Chen, JQ Wang, XY Luo, C | 2002 | Acta Mechanica Solida Sinica2002，15，3： | 15 |
| 4 | Portal vein embolization by fine needle ethanol injection :experimental and clinicalstudies显示文摘AIM To improve the technique of intraportal embolization (PVE) therapy, a new embolic method, was devised and the safety, effectiveness and feasibility were evaluated. METHODS PVE with intraportal ethanol injection via a fine needle was performed in 28 normal dogs, 22 SD rats, and 24 cirrhotic SD rats. After PVE, portography, histological and functional alteration of the liver were evaluated in dogs and rats, and the changes in portal hemodynamics as well as hepatic anatomy were observed in rats. In the clinical study, PVE by ethanol injection was performed in 61 patients with hepatocellular carcinoma under the guidance of portoechography with intraportal injection of CO 2. The effect of PVE was evaluated by ultrasonography and laparotomy. RESULTS The effectiveness and toxicity were dependent on the dose of ethanol. In the dogs, 0 25*!mg/*!kg of ethanol caused incomplete embolization with least liver damage, while 1 0*!mg/*!kg induced complete embolization with a high mortality of 57 1% (4/*!7) due to respiratory arrest. The dose of 0 5*!mg/*!kg resulted in complete embolization with slight toxicity to the liver. In the rats, the survival rate was 100% in normal group but 40 9% in cirrhotic models after ethanol injection by dose of 0 05*!mg/*!100*!g . PVE for cirrhotic rats with 0 03*!mg/*!100*!g of ethanol induced satisfactory embolization with significant hypertrophy in nonembolized lobes, and only slight damage to the hepatic parenchyma, and transient alteration in liver function, portal pressure and portal flow. In the clinical study, 12 cases with reverse portal flow were excluded judged by portoechography. Satisfactory embolization was gained in 90 2% (55/*!61) of the remaining patients determined by ultrasonography and surgery. All cases ran an uneventful postembolization course with no aberrant embolization. CONCLUSION PVE with intraportal ethanol injection of appropriate dosage via a fine needle is safe and effective and has several advantages comparing with transcatheter method. Portoechography is a mandatory approach for the prevention of aberrant embolization. | Lu MD Chen JW Xie XY Liang LJ Huang JF | 1999 | World Journal of Gastroenterology1999，5，6： | 15 |
| 5 | 血清ALT水平影响非创伤性常规指数诊断乙型肝炎相关肝硬化的准确性显示文摘【据Joural of Viral Hepatitis 2020年8月报道】题:血清ALT水平影响非创伤性常规指数诊断乙型肝炎相关肝硬化的准确性(作者Chen YP等)研究表明,FIB-4及APRI等常规指数诊断慢性乙型肝炎肝硬化、显著肝纤维化在不同研究中存在差异。近期,研究者们也先后提出了多项新的常规指数,包括红细胞体积分布宽度-血小板比值(RPR)、谷氨酰转肽酶-血小板比值(GPR)及简易肝纤维化指数(eLIFT)。为评估ALT水平对这些常规指数诊断表现的影响,1005例慢性乙型肝炎患者被纳入回顾性分析,这些患者均已接受肝活检及常规血液检查。在该研究中,似然比10、0.1的对应值分别被确定为确认诊断、排除诊断界值。 | 林小钰 陈永鹏 CHEN YP HUANG LW LIN XY | 2020 | 临床肝胆病杂志2020，36，9： | 7 |
| 6 | Improved response surface method for anti-slide reliability analysis of gravity dam based on weighted regression显示文摘The aim of this study was to design and construct an improved response surface method(RSM) based on weighted regression for the anti-slide reliability analysis of concrete gravity dam.The limitation and lacuna of the traditional RSM were briefly analyzed.Firstly,based on small experimental points,research was devoted to an improved RSM with singular value decomposition techniques.Then,the method was used on the basis of weighted regression and deviation coefficient correction to reduce iteration times and experimental points and improve the calculation method of checking point.Finally,a test example was given to verify this method.Compared with other conventional algorithms,this method has some strong advantages:this algorithm not only saves the arithmetic operations but also greatly enhances the calculation efficiency and the storage efficiency. | Jian-yun CHEN Qiang XY Jing LI Shu-li FAN Qiang xu | 2010 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2010，11，6： | 7 |
| 7 | p-Hydrazinobenzenesulfonic Acid Derivatives of Carbohydrates andTheir Capillary Zone Electrophoresis显示文摘p-Hydrazinobenzenesulfonic acid is explored as a novel ultraviolet labeling reagent for capillary electrophoresis (CE) of mono- and disaccharides. The labeling reaction takes less than 10 minutes and introduces both of absorption and charge groups into the sugars. | Wang, XY Chen, Y | 2000 | Chinese Chemical Letters2000，11，12： | 6 |
| 8 | On abiogenic natural gas显示文摘NATURAL gases usually refer to the inflammable gases dominated by methane from the angle of research on energy gases. Three genetic types of natural gases can be recognized according to the process of methane generation: (ⅰ) biogenic (bacterial) gas, mainly the gas formed by the decomposition of organic matter in sediments under the action of anaerobic bacteria; (ⅱ) thermogenic gas, mainly the gas formed by the degradation of organic matter in sediments under the action of certain temperature and pressure; (ⅲ) abiogenic gas, mainly the | Wang, XB Li, CY Chen, JF Xia, XY Guo, ZQ Xie, HS | 1997 | Chinese Science Bulletin1997，42，16： | 5 |
| 9 | Quality control measures for lowering the seroconversion rate of hemodialysis patients with hepatitis B or C virus显示文摘BACKGROUND: Hemodialysis (HD) patients are at high risk of infection by hepatitis B virus (HBV) or hepatitis C virus (HCV). The present study was designed to determine the impact of quality control measures on the prevention of transmission of blood-borne viruses. METHODS: A total of 6182 adult maintenance HD patients from all HD units in Zhejiang Province were recruited on January 1, 2007. The baseline demographic and clinical characteristics were recorded and all patients were followed up until death or survival at 4 years later. The Quality Control Standards of Hemodialysis were gradually implemented in HD units. The HBV or HCV seroconversion rates of the recruited patients were calculated and compared every year during the observation period. RESULTS: The prevalence of HBV was 8.3% at the beginning of the study, and 6.6% for HCV. With the implementation of the HD quality control measures, the HBV seroconversion rate tended to decrease year by year (χ 2 =6.620, P=0.085), and the HCV seroconversion rate decreased significantly (χ 2 =10.41, P=0.015). Compared with the data in 2007, the HBV seroconversion rate (χ 2 =4.204, P=0.040, relative risk ratio 0.393, 95% CI 0.156-0.991) and the HCV seroconversion rate (χ 2 =7.373, P=0.007, relative risk ratio 0.386, 95% CI 0.189-0.787) decreased significantly in 2010. CONCLUSION: Quality control measures for HD decreased the seroconversion rates of HBV or HCV in HD patients, showing that updated quality control measures reduce the risk for transmission of blood-borne viruses in the HD population. | Jing Yuan,Yi Yang, Fei Han, Ping Zhang, Xiao-Ying Du, Hua Jiang and Jiang-Hua Chen The Kidney Disease Center, First Affiliated Hospital, Zhejiang University School of Medicine (Yuan J, Yang Y, Han F, Zhang P, Du XY, Jiang H and Chen JH) and Hemodialysis Quality Control Center of Zhejiang Province (Yuan J, Zhang P, Du XY and Chen JH), Hangzhou 310003, China | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，3： | 2 |
| 10 | Frequent loss of membranous E - cadherin in gastric cancers: A cross - talk with Wnt in determining the fate of beta -catenin显示文摘 | Cheng XX Wang ZC Chen XY | 2005 | Clin Exp Metastasis2005，22，1： | 1 |
| 11 | Elects of assisted closure on wound microcirculation : an experimental study 显示文摘 | Chen SZ Li J Li XY | 2005 | Asian J Surg2005，3，： | 1 |
| 12 | BA case report of systemiclupus erythematosus combined with Castleman’s diseaseand literature review 显示文摘 | Xia JY Chen XY Xu F | 2012 | BRheumatol Int2012，32，7： | 1 |
| 13 | Correlation of Wnt-2 expression and beta-catenin intracellular accumulation in Chinese gastric cancers:relevance with tumour dissemination显示文摘 | Wang ZC Chen XY | 2005 | Cancer Lett2005，223，2： | 1 |
| 14 | Captopril Restores Endothelium-Dependent Relaxation Induced by Advanced Oxidation Protein Products in Rat Aorta显示文摘 | Liu LY Sun XY | 2005 | J Cardiovasc Pharmacol2005，46，6： | 1 |
| 15 | PET/MRI dual-modality tumor imaging using arginine-glycine-aspartic(RGD)-conjugated radiolabeled iron oxide nanoparticles显示文摘 | Chen K Hsu AR Chen XY | 2008 | J Nucl Med2008，49，： | 1 |
| 16 | Interferon/Peginterferon alpha plus nucleos (t) ide analogues in HBeAg - positive Chronic hepatitis B-very potent H BsAg response显示文摘 | Cao ZH Chen XY | 2010 | AASLD Abstract2010，，： | 1 |
| 17 | Purification and partial characterization of a new gastric cancer associated antigens显示文摘 | Zhang JR Zhang XY Chen XT | 1991 | Chin Med J1991，104，3： | 1 |
| 18 | Low-dose mife-pristone increases uterine natural killer cell cytotoxicity and perforin expression during the receptive phase显示文摘 | Zhou F Chen XY Zhuang YL | 2011 | Fertility and Sterility2011，96，3： | 1 |
| 19 | Low-molecular-weight heparin and early neurologic deterioration in acute stroke caused by large artery occlusive disease显示文摘 | Wang QS Chen C Chen XY | 2012 | Arch Neurol2012，69，11： | 1 |
| 20 | Tacrolimus combined with orticostemids in treatment of nephrotic idiopathic membranous nephropathy: amulticenter randomized controlled trial 显示文摘 | Chen M Li H Li XY | 2010 | Am J Med Sci2010，339，3： | 1 |
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