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| 1 | Impact of concomitant use of proton pump inhibitors and clopidogrel or ticagrelor on clinical outcomes in patients with acute coronary syndrome显示文摘BackgroundThere 是在质子泵禁止者(PPI ) 和 clopidogrel 之间的可能的不利相互作用上的大争论。另外, PPI 的使用是否少些影响 ticagrelor 遗体的临床的功效,知道。在经皮的冠的干预(一种总线标准) .MethodsWe 回顾地从 “ 分析了数据以后,我们试图与急性冠的症候群(交流)在病人在临床的结果上决定 PPI 和 clopidogrel 或 ticagrelor 的伴随物管理的影响;真实 world” ;,国际,在 2003 和 2014 之间的多中心登记( n = 15,401 )并且在1年的合成主要端点上估计了 PPI 和 clopidogrel 或 ticagrelor 的伴随物管理的影响(所有原因死亡收到 PPI 的病人更老,更经常女性,并且是更可能的有 comorbidities。没有协会为收到 clopidogrel 的病人在 PPI 使用和主要端点之间被观察(调整 HR:1.036;95% CI:0.903-1.189 ) 或 ticagrelor (调整 HR:2.320;95% CI:0.875-6.151 )(P 相互作用 = 0.2004 ) 。同样, PPI 的使用没与所有原因死亡,重新梗塞,或与交流后面的一种总线标准的为与任何一个 clopidogrel 对待的病人或 ticagrelor.ConclusionsIn 病人的严重流血的减少的风险的增加的风险被联系, PPI 的伴随物使用没在收到 clopidogrel 或 ticagrelor 的病人与不利结果的增加的风险被联系。我们的调查结果显示与 clopidogrel 或 ticagrelor 在联合使用 PPI 是合理的,特别在有胃肠的流血的更高的风险的病人。 | Yan YAN Xiao WANG Jing-Yao FAN Shao-Ping NIE Sergio Raposeiras-Roubin Emad Abu-Assi Jose P Simao Henriques Fabrizio D'Ascenzo Jorge Saucedo Jose R Gonzfilez-Juanatey Stephen B Wilton Wouter J Kikkert Ivlin Nufiez-Gil Albert Ariza-Sole Xian-Tao SONG Dimitrios Alexopoulos Christoph Liebetrau Tetsuma Kawaji Claudio Moretti Zenon Huczek Toshiharu Fujii Luis C Correia Masa-aki Kawashiril Sasko Kedev | 2016 | Journal of Geriatric Cardiology2016，13，3： | 12 |
| 2 | Standard CMOS implementation of a novel, fully differential optoelectronic integrated receiver 显示文摘 | YU C L MAO L H XIAO X D | 2009 | J of Optoelectronics Laser2009，20，4： | 1 |
| 3 | Critical role of the extracel ular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development显示文摘 | Ge C Xiao G Jiang D | | 0，，05： | 1 |
| 4 | A Simulation of Dynamic Recrystallization by Coupling a Cellular Automaton Method With a Topology Deformation Technique 显示文摘 | Xiao N M Zheng C W Li D Z | 2008 | Computational Materials Science2008，41，3： | 1 |
| 5 | Neutrophil elastase promotes lung microvascular injury and proteolysis of endothelial cadherins显示文摘 | Carden D Xiao F Moak C et a1 | 1998 | Am J Physiol1998，275，： | 1 |
| 6 | Analysis of thick functionally graded plates by using higher-or- der shear and normal deformable plate theory and MLPG method with radial basis functions显示文摘 | Gilhooley D F Batra R C Xiao J R | 2007 | Com- posite Structures2007，80，： | 1 |
| 7 | Natural variation in GS5 plays an important role in regulating grain size and yield in rice显示文摘 | Li Y B Fan C C Xing Y Z Jiang Y H Luo L J Sun L Shao D Xu C J Li X H Xiao J H He Y Q Zhang Q F | 2011 | Nature genetics2011，2，43： | 1 |
| 8 | Lymphoprolif- erative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes 显示文摘 | Xiao C Srinivasan L Calado D P | 2008 | Nat Immunol2008，9，4： | 1 |
| 9 | Intrinsic and extrinsic perfo- mance limits of graphene devices on SiO2显示文摘 | Chen J H Jang C Xiao S D | 2008 | Nanotechnolo- gy2008，3，4： | 1 |
| 10 | Ring finger protein 146/Iduna is a poly(ADP-ribose) polymer binding and PARsylation dependent E3 ubiquitin ligase显示文摘 | Zhou Z D Chan C H Xiao Z C | 2011 | Cell Adh Migr2011，5，6： | 1 |
| 11 | Indirect robust adaptive fault-tolerant control for attitude tracking of spacecraft显示文摘 | Cai W C Xiao X L Song Y D | 2008 | J of Guidance Control and Dynamics2008，31，5： | 1 |
| 12 | 查看详情显示文摘 | Song S D Zou X L Giruzzi G Xiao W W Ding X T Ding B J Ségui J L Elbèze D Clairet F Fenzi C Aniel T Artaud J F Basiuk V Bouquey F Magne R Corbel E the Tore Supra Team | | 0，，： | 1 |
| 13 | Coordinating a two-supplier and one-retailer supply chain with forecast updating 显示文摘 | Yang D Choi T M Xiao T Cheng T C E | 2011 | Automatica2011，47，7： | 1 |
| 14 | Control of postharvest botrytis fruit rot with preharvest fungicide applications in annual strawberry显示文摘 | Blacharski R W Legard D E Xiao C L | 2001 | Plant Disease2001，85，6： | 1 |
| 15 | Angiotensin-converting enzyme C-terminal catalytic domain is the main site of angiotensin 显示文摘 | FUCHS S XIAO H D HUBERT C | 2008 | Hypertension2008，51，： | 1 |
| 16 | Catalytic conversion ofcellulose to 5-hydroxymethyl furfural using acidic ionicliquids and co-catalyst显示文摘 | Ding Z D Shi J C Xiao J J | 2012 | Carbohydrate Polymers2012，90，2： | 1 |
| 17 | Natural variation in GS5 plays an important role in regulating grain size and yield in rice 显示文摘 | Li Y Fan C Xing Y Jiang Y Luo L Sun L Shao D Xu C Li X Xiao J He Y Zhang Q | 2011 | Nature Genetics2011，43，12： | 1 |
| 18 | 查看详情显示文摘 | Xiao W W Zou X L Ding X T Yao L H Feng B B Song X M Song S D Zhou Y Liu Z T Yuan B S Sun H J Ji X Q Gao Y D Li Y G Yan L W Yang Q W Liu Y Dong J Q Duan X R Liu Y Pan C H HL-2A Team | | 0，，： | 1 |
| 19 | Modelling the effects of plastic mulch on water, heat and CO2 fluxes over cropland in an arid region 显示文摘 | Yang Q D Zuo H C Xiao X | 2012 | Journal of Hydrology2012，，： | 1 |
| 20 | South China Sea sponge Biemna fortis in a cyclic carbon sterol显示文摘 | TIAN C L DENG S Z XIAO D J | 1999 | 广州化学1999，3，1： | 1 |
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