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4067篇 您的检索式:作者名="Xiao W W"
    题名 作者 年代 出处 被引量
1Reconstruction of chemically burned rat corneal surface by bone marrow-derived human mesenchymal stem cells显示文摘Ma Y Xu Y Xiao Z Yang W Zhang C Song E Du Y Li L 2006中国生物学文摘2006,20,5:58
2Spatial pattern of impervious surfaces and their impacts on land surface temperature in Beijing,China显示文摘陆地表面温度( LST )被城市的 surfacestructures 重重地影响,是在检验的城市的环境 analysis.This 学习的一个重要参数 effectimpervious 表面()空间模式在北京穿上 LST , China.A 分类 andregression 树模型(大车)被收养估计作为用二个季节与 QuickBird.LST 相结合的 Landsat imagesfrom 的一个连续变量从 Landsat 题目的 Mapper ( TM )图象被检索检验在之间的关系并且XIAO Rong-bo OUYANG Zhi-yun ZHENG Hua LI Wei-feng SCHIENKE Erich W WANG Xiao-ke 2007Journal of Environmental Sciences2007,19,2:47
31990—2017年中国伤害负担:2017年全球疾病负担研究结果(摘译)显示文摘伤害是全球性的公共卫生挑战,涉及各年龄组和不同性别的人群。过去三十年来,中国经济快速发展,人口老龄化趋势加重,社会呈现出城镇化、机动化和老龄化等特征。随着人们生活环境和生活方式的改变,伤害已跃居人群致死原因第五位,仅排在恶性肿瘤、心脑血管疾病、呼吸系统疾病和心肌梗死之后。据估计,中国每年在伤害方面消耗的直接医疗费用约为650亿元人民币.林泽婷(译) 吕来文(译) 黄晓晴(译) 李丽萍(审校) Duan Leilei Ye Pengpeng Juanita A Haagsma Jin Ye Wang Yuan Er Yuliang Deng Xiao Gao Xin Ji Cuirong Wang Linhong Marlena S Bannick W Cli Mountjoy-Venning Caitlin N Hawley Zichen Liu Mari Smith Spencer L James Theo Vos Christopher J L Murray 2020伤害医学(电子版)2020,9,2:15
4The New Synthesis of Azo Urea from Substituted Semicarbazide显示文摘Using N-bromosuccinimide and pridine as the 0xidation s}-stem to dehydrogenale anly substituted semicarbazide to form azo compounds is described for the firs1 time in this paper Nine azo conlpounds have been prepared in excellent lield under mild condition This method onle needs simple instrument and short reactionXiao Yang WANG Yu Lu WANG Jian Ping LI Cai ’Lan W’ANG Hong WANG (Department of Chemistry ,Henan Normal University Xinxiang 453002 ) 1997Chinese Chemical Letters1997,8,6:5
5观察&等待策略与手术切除治疗新辅助放化疗后达到临床完全缓解的直肠癌患者疗效比较显示文摘背景:观察&等待策略给放化疗后达到临床完全缓解(clinical complete response,cCR)的直肠癌患者提供了非创伤性的治疗选择。本研究的目的在于分析这种策略相比手术切除的远期临床疗效。方法:研究纳入来自3个中心的接受新辅助放化疗后达到cCR的Ⅱ/Ⅲ期直肠腺癌患者。cCR的评估基于直肠指诊、结肠镜和影像学检查。接受观察&等待策略的患者与接受根治性切除术的患者按照1:1比例进行倾向评分匹配分析。采用Kaplan-Meier法分析生存情况,并采用Log-rank检验进行两组间的比较。俞旻皓 WANG Q X ZHANG R XIAO W W 2021结直肠肛门外科2021,27,2:5
6Cell cycle-related kinase reprograms the liver immune microenvironment to promote cancer metastasis显示文摘The liver is an immunologically tolerant organ and a common metastatic site of multiple cancer types.Although a role for cancer cell invasion programs has been well characterized,whether and how liver-intrinsic factors drive metastatic spread is incompletely understood.Here,we show that aberrantly activated hepatocyte-intrinsic cell cycle-related kinase(CCRK)signaling in chronic liver diseases is critical for cancer metastasis by reprogramming an immunosuppressive microenvironment.Using an inducible liverspecific transgenic model,we found that CCRK overexpression dramatically increased both B16F10 melanoma and MC38 colorectal cancer(CRC)metastasis to the liver,which was highly infiltrated by polymorphonuclear-myeloid-derived suppressor cells(PMNMDSCs)and lacking natural killer T(NKT)cells.Depletion of PMN-MDSCs in CCRK transgenic mice restored NKT cell levels and their interferon gamma production and reduced liver metastasis to 2.7% and 0.7%(metastatic tumor weights)in the melanoma and CRC models,respectively.Mechanistically,CCRK activated nuclear factor-kappa B(NF-κB)signaling to increase the PMN-MDSC trafficking chemokine C-X-C motif ligand 1(CXCL1),which was positively correlated with liver-infiltrating PMN-MDSC levels in CCRK transgenic mice.Accordingly,CRC liver metastasis patients exhibited hyperaaivation of hepatic CCRK/NF-κB/CXCL1 signaling,which was associated with accumulation of PMN-MDSCs and paucity of NKT cells compared to healthy liver transplantation donors.In summary,this study demonstrates that immunosuppressive reprogramming by hepatic CCRK signaling undermines antimetastatic immunosurveillance.Our findings offer new mechanistic insights and therapeutic targets for liver metastasis intervention.Xuezhen Zeng Jingying Zhou Zhewen Xiong Hanyong Sun Weiqin Yang Myth T.S.Mok Jing Wang Jingqing Li Man Liu Wenshu Tang Yu Feng Hector Kwong-Sang W ang Shun-Wa Tsang King-Lau Chow Philip Chun Yeung John Wong Paul Bo-San Lai Anthony Wing-Hung Chan Ka Fai To Stephen Lam Chan Qiang Xia Jing Xue Xiao Chen Jun Yu Sui Peng Joseph Jao-Yiu Sung Ming Kuang Alfred Sze-Lok Cheng 2021Cellular & Molecular Immunology2021,18,4:5
7术中神经电生理监测在单椎板入路选择性神经后根离断术中的作用显示文摘目的单椎板入路选择性神经后根离断术(SL-SDR)治疗痉挛性脑瘫完全依赖术中神经电生理监测结果。本研究旨在讨论SL-SDR术中肌电图判读对神经根选择和离断的影响及作用。方法回顾分析2016年5月至2019年3月在上海交通大学附属儿童医院神经外科采用改良神经电生理监测离断方案指导下SL-SDR治疗的痉挛性脑瘫患儿的临床资料,重点关注术中肌电图判读及其与术前临床表现的相关性,以及比较采用不同神经电生理监测离断方案解读术中肌电图时的神经后根选择差异。结果共纳入318例患儿,男性231例、女性87例,平均年龄5.9岁,32例为偏瘫、161例为双侧瘫、125例为四肢瘫。每例患儿有2~8组目标肌群(术前肌张力≥2级)。术中神经电生理监测结果显示,探测的21728枚神经小根[(68.3±8.2)枚/例]中6272枚(28.9%)与肛门括约肌相关,15456枚[(48.6±7.6)枚/例]与下肢肌群相关,其中,神经后根11009枚[(34.6±7.4)枚/例]。共有3370枚[(10.6±4.7)枚/例]符合改良神经后根离断方案,其中3061枚50%部分离断、309枚75%部分离断。术前粗大运动功能分级(GMFCS)分级Ⅰ~Ⅴ级的离断率(部分离断的神经后根数/下肢肌群相关神经后根数)分别为15.8%、22.3%、33.4%、41.8%和45.7%。75%部分离断的离断率随术前GMFCS分级的递增而增加,分别为1.5%、4.8%、8.5%、14.1%和15.2%。术后3周,2068组目标肌群肌张力显著降低[(1.7±0.5)级对(2.7±0.6)级]。术前GMFCS分级Ⅰ和Ⅱ级患儿采用传统离断方案约有20%的病例无法识别任何1枚约20%需离断的神经后根,而随着患儿术前GMFCS分级的递增,传统与改良方案离断的符合率逐步提高,分别为39.5%、41.3%、52.2%、54.1%和62.8%。结论由于SL-SDR完全依赖于术中肌电图判读,使得术中神经电生理监测显得至关重要。改良神经电生理监测离断方案指导下的SL-SDR可以安全、有效治疗痉挛性脑瘫。SL-SDR术中肌电图及其与临床表现相关的预后,可以使临床医师更好地理解此类患儿脊髓神经元环路的运作模式。Xiao B Constatntini S Browd SR Zhan Q Jiang W Mei R 詹琪佳(编译) 2020中国现代神经疾病杂志2020,20,4:4
8深部地球条件下铁和氧元素的化学变化显示文摘氧与铁分别为地球上丰度最高的元素与占地球质量最大的元素,它们所形成的化合物遍布我们的星球,具有-2价的氧控制着地球的氧逸度,随着深度的增加氧逸度逐渐降低,与铁所形成的氧化物中铁的价态也逐渐降低,O/Fe逐渐增加,近些年来科学家们发现深部地球条件下铁的一系列氧化物,其中具有高压黄铁矿结构的铁超氧化物FeO2具有最高的O/Fe,并且它还能够携带一定量的H(表示为Py-FeO2H,, x=0-1)。夏群科 Liu J Hu Q Y Bi W L Yang L X Xiao Y M Chow P Meng Y.Prakapenka V B Mao H K Mao W L 2019矿物岩石地球化学通报2019,38,3:2
9Study on mechanical properties of warm compact ironbase materials 显示文摘LI Y Y NGAI T L XIAO Z Y ZHANG D T CHEN W P 2002J Cent South Univ Technol2002,9,3:2
10Genistein stimulates the osteoblastic differentiation via NO/cGMP in bone marrow culture显示文摘Pan W Quarles LD Song LH Yu YH Jiao C Tang HB Jiang CH Deng HW Li YJ Zhou HH Xiao ZS 2006中国生物学文摘2006,20,5:2
11Reconstruction of chemically burned rat corneal surface by bone marrow-derived human mesenchymal stem cells 显示文摘Ma YL Xu YS Xiao ZF Yang W Zhang C Song E 2005Stem Cells2005,24,2:1
12Magnetic field and temperature dependence of the mass of a surface polaron in polar crystals显示文摘 Eerdunchaolu W Xiao 2002J Phys Soc Jpn2002,71,5:1
13Multicycle study on chemical-looping combustion of simulated coal gas with a CaSO4 oxygen carrier in a fluidized bed reactor显示文摘SONG Q XIAO R DENG Z ZHENG W SHEN L XIAO J 2008Energy Fuels2008,22,6:1
14Directed evolution for in- creased chitinase activity显示文摘Fan Y Fang W Xiao Y 2007Applied Microbiology and Biotechnology2007,76,1:1
15The Tangshan aftershock sequence显示文摘Shedlock K Baranowski J Xiao W 1987J Geophys Res1987,92,:1
16An angle- based design approach for rectangular electrostatic tor- sion actuators 显示文摘XIAO Z X WU X T PENG W Y 2001IEEE J Mieroelectromechan Syst2001,10,4:1
17Mechanical analysis and study on structural parameter of partially earth-anchored cable-stayed bridge part one: mechanical analysis 显示文摘Zhang L W Xiao R C Xia R J 2011Applied Mechanics and Materials2011,4447,:1
18Denaturing high-performance liquid chromatography:A review显示文摘Xiao W Oefner PJ 2001Hum Mutat2001,17,6:1
19Cationic montmorillonite: Preparation and synergy with anionic polymer in filler flocculation显示文摘Liu W Ni Y Xiao H 2003JOURNAL OF PULP AND PAPER SCIENCE2003,29,5:1
20Denaturing high-performance liquid chromatography:a review显示文摘Xiao W Oefner P J 2001Hum Murat2001,17,6:1
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